Urine Acidification/Alkalinization

Adjunctive Therapy for Kidney Stone Management No Longer in Shortage

By March 13, 2017

Acetohydroxamic acid, which has proven a successful antibiotic treatment of urea-splitting Proteus infections after surgical removal of struvite stones, was in shortage since July 2014.

Albuminuria May Impact Brain Function, Up Dementia Risk

February 13, 2017

An association between albuminuria and cognitive decline may be mediated by shared microvascular pathology in the kidney and the brain.

Natural Extract May Help Prevent Growth of Kidney Stones

August 09, 2016

Hydroxycitrate, a natural fruit extract available as a dietary supplement, may dissolve a key component of kidney stones, potentially offering a new prevention tool against the condition, according to a study published online August 8 in Nature.ment that has side effects

Delay to Surgery for Nephrolithiasis Can Up Complications, Costs

May 18, 2015

Delaying surgery for nephrolithiasis can increase the risk of complications, raising health care costs, a new study finds.

Fiber Intake Tied to Reduced Kidney Stone Risk

December 30, 2014

Greater dietary intake of fiber, fruits, and vegetables is associated with a reduced risk of incident kidney stones in postmenopausal women.

Thiazide Prophylaxis for Kidney Stones: Is There a Diabetes Risk?

December 22, 2014

The risk of diabetes mellitus is not increased with thiazide diuretic prophylaxis for kidney stones, according to new research.

Lesinurad Demonstrates Efficacy in Phase 3 Gout Trials

November 17, 2014

AstraZeneca announced top-line results for two pivotal Phase 3 trials investigating lesinurad, when used in combination with xanthine oxidare (XO) inhibitor allopurinol in patients with symptomatic gout not achieving target sUA levels on current allopurinol dose.

ACP Issues Recurrent Kidney Stone Prevention Guidelines

November 04, 2014

Increased fluid intake is recommended to prevent recurrent nephrolithiasis, with pharmacological monotherapy suggested for patients in whom increased fluid intake fails to reduce stone formation.

Initial Sonography OK for Nephrolithiasis Diagnosis

September 18, 2014

No significant difference in outcomes is observed between the use of ultrasonography or computed tomography (CT) for suspected nephrolithiasis.

Predicting Second Kidney Stone Episode Risk with Nomogram

August 08, 2014

The Recurrence of Kidney Stone (ROKS) nomogram identifies patients with kidney stones who are at high risk for a second symptomatic episode.

New Guidelines on Kidney Stone Treatment Issued

July 30, 2014

Guideline statements have been developed for the diagnosis, prevention, and follow-up of patients with kidney stones, and published in the August issue of The Journal of Urology.

Burden of Unplanned Visits Post-Urinary Stone Removal

May 05, 2014

For patients undergoing procedures to fragment or remove urinary stones, one in seven require an unplanned post-procedural visit, and these visits are associated with considerable expenditure.

DASH Diet May Lower Risk of Recurrent Kidney Stones

March 03, 2014

The DASH diet may be an effective alternative to the low-oxalate diet for reducing risk of kidney stone recurrence.

Otsuka Receives Complete Response Letter for Tolvaptan in ADPKD

August 30, 2013

The FDA issued a Complete Response Letter in response to an NDA filing for tolvaptan (Otsuka) for the treatment of adult patients with rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).

Urinary Albumin Linked to More Heart Disease in Blacks

August 21, 2013

A high urinary albumin-to-creatinine ratio at baseline is associated with a higher risk of a first coronary heart disease (CHD) event in blacks compared with whites.

Urine Scent Machine May Help Detect Bladder Cancer

July 09, 2013

Odoreader, a novel GC-sensor device, may help diagnose bladder cancer by relying on the scent of a patient's urine.

Soliris Gains Orphan Drug Designation for Rare Neurological Disorder

June 28, 2013

The FDA has granted Soliris (eculizumab) Orphan Drug Designation for the treatment of neuromyelitis optica, a rare neurological disorder.