Trihexyphenidyl Tabs Rx

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Trihexyphenidyl Tabs

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Generic Name and Formulations:

Trihexyphenidyl HCl 2mg, 5mg; scored tabs.

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Indications for Trihexyphenidyl Tabs:

Adjunct in Parkinsonism. Drug-induced extrapyramidal symptoms (EPS).


Take with food. Give in 3–4 divided doses. Parkinsonism: 1mg on day 1, may increase by 2mg every 3–5 days; usual max 6–15mg/day. Concomitant levodopa: 3–6mg/day and reduce levodopa dose. EPS: 1mg on day 1; range 5–15mg/day.


Not recommended.


Tardive dyskinesia. Narrow-angle glaucoma.


Cardiovascular, renal, or hepatic disorders. Hypertension. Psychosis. GI or GU obstruction. Exposure to extreme heat. Monitor intraocular pressure. Avoid abrupt cessation. Nursing mothers.

See Also:

Trihexyphenidyl Elixir

Pharmacological Class:



Potentiates CNS depression with alcohol, CNS depressants. Antagonizes psychotropics. Additive anticholinergic effects with MAOIs. Paralytic ileus with phenothiazines, tricyclic antidepressants.

Adverse Reactions:

Anticholinergic and antihistaminic effects, confusion, anhidrosis, excitement, nausea, vomiting, angle-closure glaucoma, hallucinations, neuroleptic malignant syndrome, heat stroke, drowsiness.


Formerly known under the brand name Artane.

How Supplied:

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