Trihexyphenidyl Tabs Rx

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Trihexyphenidyl Tabs

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Generic Name and Formulations:

Trihexyphenidyl HCl 2mg, 5mg; scored tabs.

Select therapeutic use:

Indications for Trihexyphenidyl Tabs:

Adjunct in Parkinsonism. Drug-induced extrapyramidal symptoms (EPS).


Take with food. Give in 3–4 divided doses. Parkinsonism: 1mg on day 1, may increase by 2mg every 3–5 days; usual max 6–15mg/day. Concomitant levodopa: 3–6mg/day and reduce levodopa dose. EPS: 1mg on day 1; range 5–15mg/day.


Not recommended.


Tardive dyskinesia. Narrow-angle glaucoma.


Cardiovascular, renal, or hepatic disorders. Hypertension. Psychosis. GI or GU obstruction. Exposure to extreme heat. Monitor intraocular pressure. Avoid abrupt cessation. Nursing mothers.


Potentiates CNS depression with alcohol, CNS depressants. Antagonizes psychotropics. Additive anticholinergic effects with MAOIs. Paralytic ileus with phenothiazines, tricyclic antidepressants.

See Also:

Trihexyphenidyl Elixir

Pharmacological Class:


Adverse Reactions:

Anticholinergic and antihistaminic effects, confusion, anhidrosis, excitement, nausea, vomiting, angle-closure glaucoma, hallucinations, neuroleptic malignant syndrome, heat stroke, drowsiness.


Formerly known under the brand name Artane.

How Supplied:

Contact supplier.