Significant variation in mortality trends in substance use disorders among US counties

March 15, 2018

Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014.

Intensive blood pressure control not linked to changes in cerebral perfusion in cerebral small vessel disease

March 14, 2018

In patients with severe cerebral small vessel disease, a strategy of intensive blood pressure control did not significantly alter whole brain blood flow when compared to standard blood pressure control.

Compliance-linked incentives increase infant immunizations rates in rural India

March 14, 2018

Infantile immunization rates were higher among children whose caregivers received compliance-linked incentives when compared to those who received only mobile phone reminders and those who received no intervention.

Colonoscopy significantly reduces mortality from colorectal cancer in Veterans Affairs study

March 14, 2018

Colonoscopy in veterans was associated with reduced mortality from both left and right-sided colorectal cancer.

iPad app that allows patients to order tests doubles colon cancer screening rates in study

March 13, 2018

Digital health intervention resulted in significantly higher colon cancer screening rates among participants.

Stricter state firearm laws associated with lower rates of firearm suicide and homicide

March 13, 2018

Strong state firearm laws were associated with lower firearm suicide and homicide rates and overall suicide rates regardless of surrounding state laws.

No difference between tenofovir and placebo in reducing perinatal transmission of hepatitis B

March 13, 2018

Hepatitis B e-antigen (HBe-Ag) positive mothers receiving tenofovir daily from 28-weeks gestation to 2 months postpartum did not show significant reductions in HBV transmission rates compared to placebo treated participants.

Sexual minorities more likely to become pregnant as teenagers

March 12, 2018

Female sexual minorities, such as those identifying as lesbian or bisexual, were at increased risk of experiencing teen pregnancy when compared to their heterosexual peers.

Single PSA screening increases prostate cancer detection but does not change mortality

March 12, 2018

In this randomized controlled trial, men who were screened with a single PSA test had higher diagnoses of prostate cancer than those who were unscreened.

Opioids show no benefit for treating chronic musculoskeletal pain versus non-opioid treatments

March 12, 2018

In this pragmatic, randomized controlled trial, opioids did not result in better pain management or function compared to non-opioid treatments for patients with chronic pain.