De-escalation of TKI Dose in Patients with Chronic Myeloid Leukemia

By May 26, 2017

Clark, R.E. et al. "De-escalation of tyrosine kinase inhibitor dose in patients with chronic myeloid leukemia with stable major molecular response (DESTINY): an interim analysis of a non-randomised, phase 2 trial." DOI: http://dx.doi.org/10.1016/S2352-3026(17)30066-2

Cannabidiol Assessed for Drug-Resistant Seizures in the Dravet Syndrome

By May 25, 2017

Devinsky, O et al. "Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome." DOI: 10.1056/NEJMoa1611618

Ixekizumab in Psoriatic Arthritis After Inadequate Response to TNF Inhibitors

May 24, 2017

Nash, P et al. "Ixekizumab for the treatment of patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors: results from the 24-week randomised, double-blind, placebo-controlled period of the SPIRIT-P2 phase 3 trial." DOI: http://dx.doi.org/10.1016/S0140-6736(17)31429-0

Efficacy of Long-Term Denosumab Treatment Examined

By May 22, 2017

Bone HG et al. "10 years of denosumab treatment in postmenopausal women with osteoporosis: results from the phase 3 randomised FREEDOM trial and open-label extension." DOI: http://dx.doi.org/10.1016/S2213-8587(17)30138-9

Long-Acting Cabotegravir Injections in HIV-Uninfected Men

By May 22, 2017

Markowitz, M. et al. "Safety and tolerability of long-acting cabotegravir injections in HIV-uninfected men (ECLAIR): a multicentre, double-blind, randomised, placebo-controlled, phase 2a trial." DOI: http://dx.doi.org/10.1016/S2352-3018(17)30068-1

Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma

By May 22, 2017

Nair, P, MD, PhD. Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma. DOI: 10.1056/NEJMoa1703501.

Angiotensin II for Treatment of Vasodilatory Shock

By May 21, 2017

Ashish, K et al. Angiotensin II for the Treatment of Vasodilatory Shock. DOI: 10.1056/NEJMoa1704154

Treatment of Endometriosis-Associated Pain with Elagolix

By May 19, 2017

Hugh S. Taylor, MD. Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. DOI: 10.1056/NEJMoa1700089

Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease

By May 18, 2017

Lincoff, AM et al. "Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease." DOI: 10.1056/NEJMoa1609581

Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis

By May 18, 2017

Wechsler, ME et al. "Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis". DOI: 10.1056/NEJMOA1702079