Medications with depression as a possible adverse effect associated with increased risk

June 15, 2018

In this cross-sectional study, the use of medications with depression as an adverse effect was associated with a higher prevalence of depression while a similar association was not observed for medications without depression as a possible side effect.

Lower and higher oxygen saturation targets result in equal but contrasting outcomes for preemies

June 14, 2018

In this meta-analysis, there was no significant difference between lower and higher oxygen saturation targets on a primary composite of mortality or major disability at a corrected age of 18-24 months for infants born extremely preterm.

Isolated mild/moderate thrombocytopenia may not require intervention

June 11, 2018

In a review of children who presented to a specialist hematology clinic with isolated mild or moderate low platelet counts, though causes were variable, most required no interventions.

Recombinant human pentraxin 2 slows the decline in lung function in idiopathic pulmonary fibrosis

June 07, 2018

The use of recombinant human pentraxin 2 vs placebo resulted in a slower decline in lung function over 28 weeks for patients with idiopathic pulmonary fibrosis.

Survey-based intervention linked to improved communication and goals-of-care discussions

June 06, 2018

Goals-of-care (GOC) discussions were linked to improved patient outcomes and reduction of intensity in end-of-life care. The current study demonstrated that a survey-based intervention for priming clinicians with communication strategies was linked to increase in the occurrence, documentation, and quality of GOC discussions.

Improved calculations suggest major changes to statin, aspirin, and blood pressure Tx

June 06, 2018

Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.

Early endovenous ablation of leg ulcers improves healing

June 05, 2018

Patients with leg ulcers caused by superficial venous reflux treated with compression therapy experienced earlier time to healing if they were treated with early-ablation therapy and opposed to deferred-ablation.

Restrictive state alcohol policies may reduce alcohol-related crash fatalities

June 05, 2018

Increasingly restrictive state alcohol policies were associated with reduced odds that a crash fatality was alcohol related, both when blood alcohol levels were above and below the legal limit for driving in the USA (0.08%).

Viruses not linked to asthma exacerbation severity

June 04, 2018

Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure. Evidence Rating Level: 2 (Good).

Surveillance of DTaP Vaccines Reveals No New Safety Concerns

June 04, 2018

Surveillance of adverse events after diphtheria-tetanus-acellular pertussis (DTaP) vaccine administration reported to the Vaccine Adverse Event Reporting System (VAERS) between 1991 and 2016 revealed no new or unexpected adverse events.