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Tolmetin 400mg to:
Generic Name for Tolmetin 400mg
Tolmetin sodium 400mg; caps; contains sodium 36mg/cap.
Legal Classification:
Rx
Pharmacological Class for Tolmetin 400mg
NSAID.
Manufacturer of Tolmetin 400mg
Various generic manufacturers
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Indications for Tolmetin 400mg
Relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. Treatment of acute flares and the long-term management of the chronic disease. Treatment of juvenile rheumatoid arthritis.
Adult dose for Tolmetin 400mg
Initially 400mg 3 times daily. Maintenance: 600–1800mg daily in divided doses; max 1800mg/day.
Children's dosing for Tolmetin 400mg
<2yrs: not recommended. ≥2yrs: Initially 20mg/kg/day in divided doses (3–4 times daily). Maintenance: usual dose range: 15–30mg/kg/day; max 30mg/kg/day.
Also:
Contraindications for Tolmetin 400mg
Aspirin allergy. Coronary artery bypass graft surgery.
Warnings/Precautions for Tolmetin 400mg
Advanced renal disease: not recommended. Hypertension; monitor. CHF. Edema. Asthma. History of ulcer disease or GI bleeding. Bleeding disorders. Dehydration. Monitor blood, hepatic, and renal function in chronic use. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat. C: <30 weeks gestation; Cat. D: ≥30 weeks gestation: avoid). Nursing mothers: not recommended.
Interactions for Tolmetin 400mg
Avoid aspirin. May antagonize ACE inhibitors, diuretics. Increased risk of GI bleed with oral corticosteroids, anticoagulants (monitor), alcohol, smoking. Methotrexate excretion reduced. Increases lithium levels.
Adverse Reactions for Tolmetin 400mg
GI upset, abdominal pain, dyspepsia, flatulence, headache, asthenia, elevated BP, edema, dizziness, weight gain, weight loss; rash (discontinue if occurs), GI ulcer/bleed, elevated liver enzymes (discontinue if hepatotoxicity develops), blood dyscrasias, renal papillary necrosis. See literature re: risk of cardiovascular events.
How is Tolmetin 400mg supplied?
Contact supplier.