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TINDAMAX
Protozoal infections
Vaginal infections
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Drug Name:

TINDAMAX Rx

Generic Name and Formulations:
Tinidazole 250mg, 500mg; scored tabs.

Company:
Mission Pharmacal Company



Therapeutic Use:

Indications for TINDAMAX:

Giardiasis. Intestinal amebiasis. Amebic liver abscess.

Adult Dose for TINDAMAX:

Take with food. Giardiasis: 2g as a single dose. Intestinal amebiasis: 2g once daily for 3 days. Amebic liver abscess: 2g once daily for 3–5 days. Hemodialysis: see literature.

Children's Dose for TINDAMAX:

<3yrs: not recommended. Take with food. ≥3yrs: Giardiasis: 50mg/kg (max 2g) as a single dose. Intestinal amebiasis: 50mg/kg (max 2g) per day for 3 days. Amebic liver abscess: 50mg/kg (max 2g) per day for 3–5 days.

Pharmacological Class:

Nitroimidazole.

Contraindications:

Pregnancy (1st trimester).

Warnings/Precautions:

CNS disorders. Discontinue if neurological effects occur. Hepatic dysfunction. Candidiasis. Blood dyscrasias. Monitor leukocytes before and after therapy. Elderly. Pregnancy (Cat.C) (2nd and 3rd trimesters). Nursing mothers: not recommended during and for 3 days after last dose.

Interactions:

Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram. May potentiate oral anticoagulants, lithium, phenytoin. Monitor cyclosporine, tacrolimus, fluorouracil. May be antagonized by CYP450 inducers (eg, phenobarbital, rifampin), others. May be potentiated by CYP450 inhibitors (eg, cimetidine, ketoconazole). May interfere with serum chemistry tests.

Adverse Reactions:

GI upset, abdominal pain, metallic taste, anorexia, constipation, fatigue, dizziness, headache, transient leukopenia/neutropenia; rare: seizures, peripheral neuropathy.

How Supplied:

Tabs 250mg—40; 500mg—20

TINDAMAX

  • 500mg tablets (Qty:30)
  • appx. price $469.00
GoodRx

Indications for TINDAMAX:

Trichomoniasis. Bacterial vaginosis in non-pregnant women.

Adult Dose for TINDAMAX:

Take with food. Trichomoniasis: 2g as a single dose; treat consorts also. Bacterial vaginosis: 2g once daily for 2 days or 1g once daily for 5 days.

Children's Dose for TINDAMAX:

Not recommended.

Pharmacological Class:

Nitroimidazole.

Contraindications:

Pregnancy (1st trimester).

Warnings/Precautions:

CNS disorders. Discontinue if neurological effects occur. Hepatic dysfunction. Candidiasis. Blood dyscrasias. Monitor leukocytes before and after therapy. Elderly. Pregnancy (Cat.C) (2nd and 3rd trimesters). Nursing mothers: not recommended during and for 3 days after last dose.

Interactions:

Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram. May potentiate oral anticoagulants, lithium, phenytoin. Monitor cyclosporine, tacrolimus, fluorouracil. May be antagonized by CYP450 inducers (eg, phenobarbital, rifampin), others. May be potentiated by CYP450 inhibitors (eg, cimetidine, ketoconazole). May interfere with serum chemistry tests.

Adverse Reactions:

GI upset, abdominal pain, metallic taste, anorexia, constipation, fatigue, dizziness, headache, transient leukopenia/neutropenia; rare: seizures, peripheral neuropathy.

How Supplied:

Tabs 250mg—40; 500mg—20

TINDAMAX

  • 500mg tablets (Qty:30)
  • appx. price $469.00
GoodRx

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