Findings suggested that the rate of in-hospital mortality after pediatric stroke was 1.5% for neonates and 3.1% in children/adolescents. The authors also found that the strongest risk factors for mortality were congenital heart disease and stroke that involved both anterior and posterior circulation.
Results showed that compared to metoprolol, those who initiated carvedilol had a greater all-cause (HR, 1.08; 95% CI,1.02-1.16) and cardiovascular mortality (HR, 1.18; 95% CI, 1.08-1.29).
"These data support limits for alcohol consumption that are lower than those recommended in most current guidelines," the authors write.
The researchers identified significant inverse associations between coffee consumption (more than 3 cups/day) and CAC ≥100 (odds ratio, 0.33 for more than three cups/day).
"Although outcomes-based pricing may have a role in other settings, our analysis of its application to PCSK9 inhibitors - effective preventive medications with a high price tag - shows the potential limitation of this approach for high-cost preventive therapies," the authors write.
The researchers found that oral anticoagulation therapy was initiated within 30 days post-discharge in 8.4 and 42.9% of those with POAF and NVAF, respectively.
Patients with higher modified Rankin Scale (mRS) levels had worse scores, though the association between scores and mRS level varied. Physical function, satisfaction with social roles, and executive function were the most affected domains.
Using Medicaid claims from 5 states (1999-2010) and Medicare claims for dual-enrollees, study authors analyzed the first concomitant use of clopidogrel and 1 of 10 selected NSAIDs (ibuprofen, celecoxib, naproxen, rofecoxib, meloxicam, diclofenac, indomethacin, valdecoxib, nabumetone, etodolac) after a 1-year baseline period.
The primary efficacy outcome was the combined rate of death from a cardiovascular cause, heart attack, stroke due to inadequate blood supply, blood clots or amputation due to cardiovascular disease.
The ODYSSEY Outcomes trial (N=18,924) evaluated the effect of alirocumab on the occurrence of MACE in patients who had an ACS between 1-12 months prior to trial enrollment, and who were already taking maximally-tolerated statins (atorvastatin or rosuvastatin).
After 30 days of treatment the analysis found that major bleeding - the most common complication with blood thinners - occurred at the same level (0.7%) for patients in both treatment groups
Aspirin comparable to rivaroxaban for extended venous thromboembolism prophylaxis following arthroplasty
Patients initially treated with rivaroxaban following total knee or hip arthroplasty experienced similar rates of venous thromboembolism (VTE) regardless of continued rivaroxaban use or switching to aspirin for extended VTE prophylaxis.
Patients presenting with ischemic stroke 6 to 16 hours after they were last known to be well had improved functional outcomes at 90 days if treated with thrombectomy and medical therapy compared to medical therapy alone.
The Agency is asking healthcare professionals to use caution before prescribing the antibiotic to this patient population.
Results showed the crude hazard ratio (HR) of major cardiovascular events was 1.99 (95% CI, 1.28-3.09) for COX-2 vs. nonselective NSAIDs.
The Trevo device is inserted via a catheter into the blood vessel to the site of the clot. The end portion of the device expands (up to 3-6mm diameter) and grips the clot, allowing the physician to pull it back through the vessel along with the device.
The Viz.AI Contact application is a computer-aided triage software that uses an artificial intelligence algorithm to analyze images for indicators associated with a stroke.
In this study about quality of care for patients with TIA or minor stroke, there was substantial variation in adherence to guidelines for patients treated at Veteran's Affairs (VA) hospitals across the country.
A preoperatively diagnosed patent foramen ovale was associated with an increased risk of stroke within 30 days of non-cardiac surgery. With Evidence Rating Level: 2 (Good).
The researchers found that in 8 studies which included ischemic and hemorrhagic stroke, women had worse outcomes than men, with significantly lower odds of good outcome or increased odds of poor outcome.
There were 850 ischemic strokes (0.6%) within 30 days of surgery: 3.2 and 0.5% among patients with and without PFO, respectively.
There was a statistically significantly smaller loss of mass (mg) for the hand (P<0.001) and the PillTool (P<0.001) versus the knife and the Pilomat.
There were positive associations for migraine with myocardial infarction, ischemic stroke and hemorrhagic stroke, venous thromboembolism, and atrial fibrillation or flutter.
At 90 days, the prevalence of venous thromboembolism varied from 0.3 to 1.37% for all patients and from 0.75 to 3.86% for hospitalized patients.