Thromboembolic Disorders

Major Cardiac Event Risks Among Minorities Examined Following PCI

October 19, 2017

But women and minorities have higher adjusted risk of death/MI after PCI with everolimus-eluting stent

Expert Consensus Published for Mitral Regurgitation Management

October 19, 2017

"This expert consensus decision pathway provides the clinician with additional tools to improve the care of MR patients," the authors write. "It can serve as a guide to patient assessment and individualized decision making."

Appropriate Use Criteria Created for Heart Condition

October 18, 2017

SAVR or TAVR appropriate for most patients with symptomatic AS at intermediate or high surgical risk.

Safety of Direct Oral Anticoagulant in VTE Examined

October 18, 2017

Researchers conducted a retrospective matched cohort study to examine the safety of DOAC versus warfarin use for treatment of venous thromboembolism. Direct Oral Anticoagulant VTE

PPI Use and First-Time Stroke, MI: What's the Link?

October 18, 2017

After adjustment for age, sex, comorbidities, and concomitant medications, the rates of ischemic stroke and MI were significantly increased with current PPI exposure (hazard ratios, 1.13 and 1.31).

Thrombosis Risks Assessed for Bioresorbable Scaffolds vs. Metallic Stents

October 17, 2017

The safety and efficacy of everolimus-eluting bioresorbable vascular scaffolds was evaluated compared to everolimus-eluting metallic stents using data from 7 randomized trials and 38 observational studies.

Anticoagulants Taken With Certain Meds May Up Bleeding Risk

October 05, 2017

And antithrobotic medications linked to higher rate of hematuria-related events in older adults

Warfarin Dosing Based on Genotype May Reduce Adverse Events

September 27, 2017

Overall, 808 and 789 patients in the genotype-guided and clinically-guided groups, respectively, completed the trial.

Low-Dose Oxygen Assessed in Post-Acute Stroke Care

September 27, 2017

The researchers found that no subgroup benefited from oxygen.

Bleomycin Sclerotherapy Efficacy Tested in Vascular Malformations

September 22, 2017

There was significant improvement in all lesions of capillary malformation with nodular change and lymphatic malformation, as well as in 82.4% of lesions of venous malformation.

Portable DVT Prevention Device Now Available

By September 21, 2017

As well as preventing DVT the company indicates that PlasmFlow can be used to enhance blood circulation, reduce post-operative pain and swelling, aid in the treatment of stasis dermatitis, venous stasis ulcers, arterial and diabetic leg ulcers, chronic venous insufficiently and reduce of edema in the lower limbs.

Pioglitazone Efficacy in Patients at High Risk of Recurrent Stroke

September 19, 2017

The researchers found that the five-year risk for stroke or MI was 6.0% in the pioglitazone group compared with 7.9% in the placebo group, among patients with lower baseline risk.

Effects of Statin Use as Primary Prevention Examined in Older Males

September 18, 2017

The researchers found that over the study period statin use was associated with an 18% lower risk of all-cause mortality and non-significantly lower risk of CVD events and stroke.

Airplane Medical Emergencies: Is it a Physician's Duty to Help?

September 13, 2017

In the United States, Canada, and United Kingdom, physicians do not have the legal duty to assist unless there is a prior patient-physician relationship.

Increase in Atrial Stiffness During First 30-Minutes of Post E-Cig Inhalation

September 12, 2017

The researchers found that during the first 30 minutes following e-cigarette inhalation with nicotine, there was a significant increase in blood pressure, heart rate and arterial stiffness.

Higher Incidence of GI Symptoms in Female IBS Patients on Clopidogrel

By September 11, 2017

The results showed a higher proportion of patients with GI symptoms on clopidogrel (68%) compared to controls (60%, P=0.0011) that were Females (70% vs. 60%, P=0.0003) not Males (61 vs. 60%; P=0.8312).

Venous Thromboembolism and Body Height: What's the Link?

September 11, 2017

Study using sibling pairs discordant for height reduces chance of familial confounding

Recall Initiated for Multiple Lots of Activase

By September 07, 2017

Genentech is informing its customers and distributors and is arranging for return of all impacted products.

Does Long-Term Aspirin Benefit Low Risk Afib Ablation Patients?

September 05, 2017

Low risk patients do not appear to benefit from long-term aspirin therapy, but bleeding risk up

Link Between Cardiovascular Med Use and Cognitive Impairment Explored

September 01, 2017

No link for impaired cognition, antihypertensive, antithrombotic, lipid-modifying agent use

CABG vs. PCI in Patients with Type 1 Diabetes and Multivessel Disease

August 30, 2017

Compared with CABG, PCI was associated with similar risks of all-cause mortality, and with elevated risks of coronary heart disease mortality, myocardial infarction, and repeat revascularization.

Carbs More Likely to Kill than Fats, Says New Study

August 30, 2017

The investigators found that high-carbohydrate diets are common, with more than half of the people deriving 70 percent of their daily calories from carbs.

Apixaban Compared to Standard Care in NVAF Patients Undergoing Cardioversion

By August 30, 2017

This is an investigational use for Eliquis.

Does Oxygen Therapy Reduce Mortality in Suspected Acute MI?

August 30, 2017

Routine use of supplemental oxygen does not reduce one-year all-cause mortality versus ambient air

For STEMI Patients, Mineralocorticoid Antagonists May Up Survival

By August 29, 2017

MRAs such as spironolactone and eplerenone are "still underused in routine clinical practice" but can be effective in countering the harms of high aldosterone levels, explained study author Professor Farzin Beygui, MD, PhD.

Bivalirudin Compared with Heparin Monotherapy Among Patients Undergoing PCI

August 29, 2017

Researchers enrolled patients with ST-segment elevation myocardial infarction (STEMI) or non-STEMI (NSTEMI) who were undergoing PCI and receiving a potent P2Y12 inhibitor to receive bivalirudin or heparin during PCI.

Type 2 Diabetes Treatment Approved to Reduce Risk of MACE

By August 28, 2017

The Food and Drug Administration (FDA) approval was based on data from the randomized, double-blind, placebo-controlled LEADER trial (n=9,340) that evaluated long-term effects of Victoza vs. placebo in patients with type 2 diabetes with high risk of major cardiovascular events (MACE).

Bleeding Risk Reduced with Dabigatran Dual Tx vs. Warfarin Triple Tx

By August 28, 2017

The primary safety endpoint was defined as time to major bleeding events and clinically relevant non-major bleeding events when compared to triple therapy with warfarin.

Canakinumab Tied to Significantly Lower Incidence of Recurrent CV Events

August 28, 2017

150-mg dose met prespecified threshold for significance for primary and secondary end points

Risk of MACE Significantly Lower with Rivaroxaban Plus Aspirin

August 28, 2017

Primary outcome for fewer patients receiving rivaroxaban plus aspirin, but more major bleeding