TENORMIN Rx

Indications for TENORMIN:

Long-term management of angina.

Adult Dose for TENORMIN:

Initially 50mg once daily. May increase after 1 week to 100mg daily; max 200mg/day. Elderly or renal impairment: may need lower dose; monitor trough BP. Coincide a dose for the end of hemodialysis.

Children's Dose for TENORMIN:

Not recommended.

Pharmacological Class:

Cardioselective beta-blocker.

Contraindications:

Sinus bradycardia. 2^nd- or 3^rd-degree heart block. Overt heart failure. Cardiogenic shock.

Warnings/Precautions:

Bronchospastic disease. Renal dysfunction. Diabetes. Hyperthyroidism. Pheochromocytoma. Surgery. Avoid abrupt cessation. Peripheral circulatory disorders. Ischemic heart disease or failure. Pregnancy (Cat.D): not recommended. Nursing mothers.

Interactions:

Additive effect with catecholamine-depleting drugs, prazosin, digoxin. Conduction abnormalities, bradycardia, heart block with calcium channel blockers (esp. verapamil, diltiazem). Increased rebound hypertension with clonidine withdrawal. May block epinephrine.

Adverse Reactions:

Heart failure, bronchospasm, bradycardia, angina, MI, heart block, dizziness, fatigue, GI upset, depression, orthostatic hypotension, cold extremities.

How Supplied:

Tabs 25mg, 100mg—100; 50mg—100, 1000

Indications for TENORMIN:

Hypertension.

Adult Dose for TENORMIN:

Initially 50mg daily. May increase after 1–2 weeks to 100mg once daily; max 100mg/day. Elderly: Initially 25–50mg daily; monitor trough BP. CrCl 15–35mL/minute: max 50mg/day; CrCl <15mL/minute: max 25mg/day; monitor trough BP. Coincide a dose for the end of hemodialysis.

Children's Dose for TENORMIN:

Not recommended.

Pharmacological Class:

Cardioselective beta-blocker.

Contraindications:

Sinus bradycardia. 2^nd- or 3^rd-degree heart block. Overt heart failure. Cardiogenic shock.

Warnings/Precautions:

Bronchospastic disease. Renal dysfunction. Diabetes. Hyperthyroidism. Pheochromocytoma. Surgery. Avoid abrupt cessation. Peripheral circulatory disorders. Ischemic heart disease or failure. Pregnancy (Cat.D): not recommended. Nursing mothers.

Interactions:

Additive effect with catecholamine-depleting drugs, prazosin, digoxin. Conduction abnormalities, bradycardia, heart block with calcium channel blockers (esp. verapamil, diltiazem). Increased rebound hypertension with clonidine withdrawal. May block epinephrine.

Adverse Reactions:

Heart failure, bronchospasm, bradycardia, angina, MI, heart block, dizziness, fatigue, GI upset, depression, orthostatic hypotension, cold extremities.

How Supplied:

Tabs 25mg, 100mg—100; 50mg—100, 1000