Diclofenac sodium 1% gel is well tolerated for up to 1 year for the relief of osteoarthritis (OA) pain in patients both <65 years and ≥65 years of age, according to 12-month data presented at the American Pain Society's 31st Annual Scientific Meeting.
May 18, 2012
For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness and visual analog score) (DAS28-P) at baseline are predictive of less improvement in pain at one year.
Minimal systemic distribution of topical diclofenac sodium gel resulted in a lower incidence of major or moderate drug-drug interactions associated with oral diclofenac and reduced the risk of drug interaction-related adverse events. Study results were reported by Matthew Wieman, MD, from Endo Pharmaceuticals, John H. Peniston, DO, from Novartis Consumer Health, and colleagues at the American Pain Society's 31st Annual Scientific Meeting.
Study investigators presented data from the UPLOAD (Understanding Pain & Limitations in OsteoArthritic Disease) study at the American Pain Society's 31st Annual Scientific Meeting demonstrating that hydroxyvitamin D levels <25ng/mL were associated with an increase in osteoarthritis (OA) symptoms and a decreased threshold for pressure pain.
May 09, 2012
Children with juvenile idiopathic arthritis (JIA) have higher rates of hospitalized bacterial infection than children without the condition, and high-dose steroids significantly increase the rate of infection.