Not interchangeable with vardenafil (Levitra) 10mg film-coated tabs. Take without liquid. Place one tablet on tongue, about 1 hour before sexual activity; max 1 tab/day. Concomitant α-blockers: use lower doses of vardenafil film-coated tabs as initial therapy.
Phosphodiesterase type 5 inhibitor (cGMP-specific).
Concomitant nitrates, or nitric oxide donors.
Confirm diagnosis. Congenital QT prolongation: avoid use. Cardiovascular disease (eg, unstable angina; systolic BP<90 or BP>170/110; recent stroke, life-threatening arrhythmia, or MI (within 6 months); severe cardiac failure; LV outflow obstruction), moderate or severe hepatic impairment, renal dialysis, retinitis pigmentosa, and related retinal disorders: not recommended. Anatomical penile deformation. Predisposition to priapism. Bleeding disorders. Active peptic ulcer. Fructose intolerance. Pregnancy (Cat.B).
See Contraindications. Avoid Class IA (eg, quinidine, procainamide) or Class III (eg, amiodarone, sotalol) antiarrhythmics, others that cause QT prolongation. Hypotension with nitrates, α-blockers, other antihypertensives. Concomitant moderate or potent CYP3A4 inhibitors (eg, erythromycin, grapefruit juice, clarithromycin, ketoconazole, itraconazole, indinavir, saquinavir, atazanavir, ritonavir), or other erectile dysfunction treatments: not recommended. Caution with α-blockers.
Headache, flushing, nasal congestion, dyspepsia, dizziness, back pain, sudden vision or hearing loss (discontinue if occurs), cardiovascular effects (eg, hypotension, tachycardia), QT prolongation; rare: priapism.
Tabs (blister cards)—1 x 4, 10 x 4