STAXYN Rx

Indications for STAXYN:

Erectile dysfunction.

Adult Dose for STAXYN:

Not interchangeable with vardenafil (Levitra) 10mg film-coated tabs. Take without liquid. Place one tablet on tongue, about 1 hour before sexual activity; max 1 tab/day. Concomitant α-blockers: use lower doses of vardenafil film-coated tabs as initial therapy.

Children's Dose for STAXYN:

Not recommended.

Pharmacological Class:

Phosphodiesterase type 5 inhibitor (cGMP-specific).

Contraindications:

Concomitant nitrates, or nitric oxide donors.

Warnings/Precautions:

Confirm diagnosis. Congenital QT prolongation: avoid use. Cardiovascular disease (eg, unstable angina; systolic BP<90 or BP>170/110; recent stroke, life-threatening arrhythmia, or MI (within 6 months); severe cardiac failure; LV outflow obstruction), moderate or severe hepatic impairment, renal dialysis, retinitis pigmentosa, and related retinal disorders: not recommended. Anatomical penile deformation. Predisposition to priapism. Bleeding disorders. Active peptic ulcer. Fructose intolerance. Pregnancy (Cat.B).

Interactions:

See Contraindications. Avoid Class IA (eg, quinidine, procainamide) or Class III (eg, amiodarone, sotalol) antiarrhythmics, others that cause QT prolongation. Hypotension with nitrates, α-blockers, other antihypertensives. Concomitant moderate or potent CYP3A4 inhibitors (eg, erythromycin, grapefruit juice, clarithromycin, ketoconazole, itraconazole, indinavir, saquinavir, atazanavir, ritonavir), or other erectile dysfunction treatments: not recommended. Caution with α-blockers.

Adverse Reactions:

Headache, flushing, nasal congestion, dyspepsia, dizziness, back pain, sudden vision or hearing loss (discontinue if occurs), cardiovascular effects (eg, hypotension, tachycardia), QT prolongation; rare: priapism.

How Supplied:

Tabs (blister cards)—1 x 4, 10 x 4