Sleep-wake Disorders

Obstructive Sleep Apnea and Elevated Blood Coagulability: Is There a Link?

August 18, 2017

Significant differences were identified in PT seconds for the control group versus the moderate and severe OSA groups (mean, 11.26 versus 10.74 and 10.67, respectively).

CPAP Adherence Increases After Patients View Video of Themselves

July 25, 2017

"People who watched themselves gasping and struggling to breathe with sleep apnea used their CPAP machines three hours more per night than those who saw no video," said Mark Aloia, PhD, National Jewish Health in Denver.

PANS/PANDAS Treatment Guidelines Released

By July 20, 2017

"Immunomodulatory therapy should be considered early, because NSAIDs or a short course of oral corticosteroids may be sufficient for symptom remission in recent-onset cases, whereas those with long-standing symptoms often require more intensive and prolonged immunotherapeutic interventions," the authors write.

More Sleep May Help Stave off Alzheimer's in Those At Risk

July 07, 2017

The researchers found an association between greater AD pathology and worse subjective sleep quality, more sleep problems, and daytime somnolence.

Day Sleepers May Be More Susceptible to Oxidative DNA Damage

June 28, 2017

The researchers also saw evidence that lower melatonin levels correlated with lower 8-OH-dG. The 50 workers in the latest study were those who'd shown the biggest drop in melatonin during night work versus night sleep.

Insomnia Drug May Help Patients with Disorders of Consciousness, Movement

By June 26, 2017

Researchers reviewed a total of 2,314 articles for zolpidem used to treat neurologic disorders across various databases.

Anti-TNF-α Evaluated for Sleep Quality Effects in Ankylosing Spondylitis

June 23, 2017

The researchers found that 57.9% of all patients had impaired SQ in baseline evaluation. Obstructive apnea syndrome, snoring, and periodic leg movements were seen with PSG in 73.7, 74.4, and 26.3% of patients, respectively.

Antihistamine Overdose in Patient with Insomnia and RLS

By June 13, 2017

In this case, a 57-year-old Caucasian woman presented with hypersomnolence and altered mental status after having ingested 20-30 diphenhydramine 25mg tablets.

Sleep Disorder Treatment Linked to Serious Skin Side Effect

By June 12, 2017

Serious rash, including SJS, is a reported adverse event in the prescribing information for both modafinil and armodafinil.

Delayed Eating Linked to Increases in Weight, Cholesterol, Fasting Glucose

June 08, 2017

Compared with daytime eating, delayed eating also linked to increases in respiratory quotient

'Social Jet Lag' May Contribute to Acute Health Outcomes

June 08, 2017

Researchers found the disrupted sleep pattern to be linked with cardiovascular disease, depression, fatigue, and daytime sleepiness.

Old Anti-Nausea Agent May Be Effective for Sleep Apnea

By June 07, 2017

"Expanded and pivotal clinical trials must still be conducted to fully establish the best approach to cannabinoid therapy in obstructive sleep apnea," said lead author Professor David Carley.

JZP-110 Effective for Excessive Sleepiness in OSA Patients

By June 06, 2017

Significant overall improvements were also noted on the key secondary endpoint of improved Patient Global Impression of Change (PGIc) scale, with 90% of patients in the 150mg and 300mg arms reporting overall improvement at Week 12.

Diagnostic Patch Effectively IDs Sleep Apnea

By June 05, 2017

This lightweight skin-adhesive diagnostic patch is able to record nasal pressure, blood oxygen saturation, pulse, respiratory effort, sleep time, and body position.

Sleep Duration Linked to Tx Response in Depressed Patients with Insomnia

By June 05, 2017

Findings from the study suggest that a shorter sleep duration may be a risk factor for refractory depression.

Stair Walking Beats Caffeine in Sleep Deprived Adults

May 05, 2017

A 10-minute climb can increase both fitness and motivation, researcher says

Hip Fracture Risk Up in New Users of Sleep Aids

May 03, 2017

New users of sleep aids have fracture rate 2.5 times greater than peers not taking these drugs

Sleep Duration May Affect Prostate Cancer Mortality

April 04, 2017

Six hours of sleep a night was linked to a 29% higher risk of prostate cancer death compared to 7 hours. Men who were 65 or older showed no difference in the risk of death from prostate cancer.

Sleeping Difficulties May Up Risk of Cardio, Stroke Events

By March 31, 2017

Analysis showed there were significant associations between sleep issues and the risk of heart disease and stroke; a relative risk increase of 1.27 for difficulty initiating sleep, 1.11 for difficulty maintaining sleep, and 1.18 for non-restorative sleep.

Sleep Disorder Tx May Have Knock-On Benefit to Nocturia Symptoms

March 28, 2017

After starting CPAP, nighttime urination was reduced in 65% patients who had to get up more than once during the night to urinate.

Cutting Salt May Indirectly Help with Sleep Problems

March 27, 2017

An easy way for patients to reduce nighttime urination and subsequent impact on sleep

Novel Drug Shows Promise for Excessive Sleepiness in OSA

By March 20, 2017

Both demonstrated highly statistically significant improvement in the co-primary endpoints of Maintenance of Wakefulness test and the Epworth Sleepiness scale, for JZP-110 versus placebo.

Sleep Duration Analyzed by Occupation

By March 17, 2017

The CDC analysis was based on data from adults surveyed for the 2013 and 2014 Behavioral Risk Factor Surveillance System (BRFSS) in 29 states.

New Sleep Apnea Management Guidelines Issued

By March 15, 2017

Six recommendations were developed to guide clinicians in diagnosing obstructive sleep apnea.

VIDEO: Certain Drugs May Improve Cognitive Abilities in Chess Players

March 10, 2017

To examine any potential cognitive improvement, researchers conducted a crossover study of modafinil, methylphenidate, caffeine and placebo.

Sleep Interventions Reviewed for Children with ASD

By March 09, 2017

Researchers reviewed five interventions, included melatonin, drug therapy other than melatonin, alternative therapies (ie, massage, aromatherapy, multivitamin/iron supplementation), behavioral interventions and parent education/education programs.

Concussion Frequency, Symptoms Differ Between the Genders

March 03, 2017

Female athletes appear to be more likely than males to suffer concussions during their careers on the field, according to a new study by researchers at Columbia University, New York.

Insomnia Rx Choice Often Dictated by Past Prescribing Behavior

March 02, 2017

Historical preference highly predictive of future prescribing behavior

New Warning Added to Antipsychotic Drug Labeling

By February 27, 2017

The FDA has approved updates to all antipsychotic medication labels to specifically warn of somnolence, postural hypotension, and motor and sensory instability risks.

Antidepressants Often Prescribed for Unapproved Uses

February 23, 2017

Trazodone for insomnia most common off-label use for antidepressants