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Imaging agents
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Generic Name and Formulations:

Diatrizoate meglumine 527mg, iodipamide meglumine 268mg; per mL; soln for intrauterine instillation; contains sodium 0.91mg/mL, organically bound iodine 380mg/mL.

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Indications for SINOGRAFIN:



See literature for information on administration and radiography. Empty bladder before exam. 3–4mL administered in fractional doses of approx. 1mL are usually adequate to visualize the uterus; an additional 3–4mL will demonstrate the tubes. Total doses of 1.5–10mL have been used.


Not established.


Pregnancy. During menstrual period. External genitalia or genital tract infection. Within 30 days of curettage or conization or within 6 months following termination of pregnancy.


Should be performed by personnel trained in diagnostic procedures that involve radiopaque diagnostic agents. Carcinoma of the uterus and/or uterine/tubes; possible dispersion of carcinogenic cells during procedure. History of asthma/allergy. Nursing mothers.


May interfere with thyroid tests.

Pharmacological Class:

Radiopaque contrast medium.

Adverse Reactions:

Dizziness, syncope, hypotension, chills, fever, nausea, vomiting, abdominal pain and tenderness, hypersensitivity reactions; rare: bradycardia, hypotension, cardiac arrest, death.

How Supplied:

Single-dose vial (10mL)—10