SINGULAIR Rx

Indications for SINGULAIR:

Seasonal allergic rhinitis (for patients ≥2 years old). Perennial allergic rhinitis (for patients ≥6 months old).

Adults and Children's Dose:

Take granules by mouth within 15 minutes of opening packet; may dissolve in 5mL of cold or room temperature baby formula or breast milk, or mix in spoonful of soft applesauce, carrots, rice, or ice cream. <6months w/perennial allergic rhinitis or <2yrs w/seasonal allergic rhinitis: not established. 6–23months: one 4mg granule packet. 2–5yrs: one 4mg chew tab or granule packet. 6–14yrs: one 5mg chew tab. ≥15yrs: one 10mg tab. For all: take once daily.

See Also:

SINGULAIR CHEWABLE

SINGULAIR ORAL GRANULES

Pharmacological Class:

Leukotriene receptor antagonist.

Warnings/Precautions:

Caution when withdrawing from oral steroids. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Monitor with potent CYP450 inducers (eg, phenobarbital, rifampin).

Adverse Reactions:

Upper respiratory infection, fever, headache, pharyngitis, cough, abdominal pain, diarrhea, otitis media, influenza, rhinorrhea, sinusitis; neuropsychiatric events (monitor).

Metabolism:

Hepatic (CYP3A4, CYP2C9, CYP2C8). >99% protein bound.

Elimination:

Fecal.

Generic Availability:

YES

How Supplied:

Tabs, chew tabs—30, 90; Oral granules—30

Indications for SINGULAIR:

Prophylaxis and chronic treatment of asthma (for patients ≥12 months old). Prevention of exercise-induced bronchoconstriction (EIB) (for patients ≥6yrs old).

Adults and Children's Dose:

Take granules by mouth within 15 minutes of opening packet; may dissolve in 5mL of cold or room temperature baby formula or breast milk, or mix in spoonful of soft applesauce, carrots, rice, or ice cream. <12months w/asthma or <6yrs w/EIB: not established. 12–23months: one 4mg granule packet. 2–5yrs: one 4mg chew tab or granule packet. 6–14yrs: one 5mg chew tab. ≥15yrs: 10mg. For asthma: take once daily in the PM. For EIB: Take at least 2 hours before exercise (max 1 dose/day). Do not take an additional dose within 24hrs of a previous dose or if already taking a daily dose for another indication.

See Also:

SINGULAIR CHEWABLE

SINGULAIR ORAL GRANULES

Pharmacological Class:

Leukotriene receptor antagonist.

Warnings/Precautions:

Not for primary treatment of acute attack. Eosinophilic conditions. Caution when withdrawing from oral steroids. Aspirin sensitivity. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Monitor with potent CYP450 inducers (eg, phenobarbital, rifampin).

Adverse Reactions:

Upper respiratory infection, fever, headache, pharyngitis, cough, abdominal pain, diarrhea, otitis media, influenza, rhinorrhea, sinusitis; neuropsychiatric events (monitor).

Metabolism:

Hepatic (CYP3A4, CYP2C9, CYP2C8). >99% protein bound.

Elimination:

Fecal.

Generic Availability:

YES

How Supplied:

Tabs, chew tabs—30, 90; Oral granules—30