RX (Prescription Only) Oral Allergy Treatments
| RX (PRESCRIPTION ONLY) ORAL ALLERGY TREATMENTS** | ||||
|---|---|---|---|---|
| Generic & Class | Brand & Company | Strength | FormulationsΔ | Usual Dose |
| FIRST GENERATION H1 ANTAGONIST ANTIHISTAMINE | ||||
| Carbinoxamine maleate | ARBINOXA
(Hawthorn) |
4mg | tabs+ | Children: <2yrs: contraindicated. 2–5yrs: 0.2–0.4mg/kg/day
in 3–4 divided doses. 6–11yrs: 2–4mg 3–4 times daily.
Adults: 4–8mg orally 3–4 times daily. |
| ARBINOXA ORAL SOLUTION
(Hawthorn) |
4mg/5mL | soln | ||
| PALGIC
(PamLab) |
4mg | tabs+ | Adults and Children: <1year: not recommended. 1–6years: 2mg daily as needed; max 0.2–0.4mg/kg per day in divided doses 6–8hrs apart. ≥6years: 4mg daily as needed; max 24mg/day in divided doses 6–8hrs apart. | |
| PALGIC ORAL SOLUTION
(PamLab) |
4mg/5mL | soln | ||
| Cyproheptadine HCl | CYPROHEPTADINE HCL
(various) |
4mg | tabs+ | Children: <2yrs: not recommended. 2–6yrs: 2mg 2–3 times
per day; max 12mg daily. 7–14yrs: 4mg 2–3 times per day; max 16mg daily.
Adults: ≥14yrs: initially 4mg 3 times daily; usual range 12–16mg/day; max 0.5mg/kg per day. |
| Hydroxyzine HCl | HYDROXYZINE HCL
(various) |
10mg, 25mg, 50mg, 100mg | tabs | Children: <6years: 50mg daily. ≥6years:
50–100mg daily. Both in divided doses.
Adults: 25mg 3–4 times daily. |
| HYDROXYZINE HCL SYRUP‡
(various) |
10mg/5mL | syrup | ||
| Hydroxyzine pamoate | VISTARIL
(Pfizer) |
25mg, 50mg | caps | Children: <6years: 50mg daily. ≥6years:
50–100mg daily. Both in divided doses.
Adults: 25mg 3–4 times daily. |
| SECOND GENERATION H1 ANTAGONIST ANTIHISTAMINE | ||||
| Desloratadine | CLARINEX
(Merck) |
5mg | tabs | Children: Use other forms.
Adults: 5mg once daily. Renal or hepatic impairment: initially 5mg every other day. |
| CLARINEX REDITABS*
(Merck) |
2.5mg, 5mg | ODT | Adults and Children: Dissolve on tongue; swallow with or without water. <6years: use other forms. 6–11years: 2.5mg once daily. ≥12years: 5mg once daily. Renal or hepatic impairment: initially 5mg every other day. | |
| CLARINEX SYRUP
(Merck) |
0.5mg/mL | syrup | Adults and Children: <6months: not recommended. 6–11months: 1mg (2mL). 1–5years: 1.25mg (2.5mL). 6–11years: 2.5mg (5mL). ≥12years: 5mg (10mL). All: once daily. | |
| Levocetirizine dihydrochloride | XYZAL
(UCB and Sanofi Aventis) |
5mg | tabs+ | Children: <6months: not recommended.
6months–5years: max 1.25mg once daily in the PM. 6–11years: max 2.5mg once daily
in the PM. Renal dysfunction: contraindicated.
Adults: 2.5mg–5mg once daily in the PM. Renal dysfunction: CrCl 50–80mL/min: 2.5mg once daily; CrCl 30–50mL/min: 2.5mg every other day; CrCl 10–30mL/min: 2.5mg twice per week (every 3–4 days); CrCl <10mL/min or hemodialysis: contraindicated. |
| XYZAL ORAL SOLUTION
(UCB and Sanofi Aventis) |
0.5mg/mL | soln | ||
| LEUKOTRIENE RECEPTOR ANTAGONIST | ||||
| Montelukast (as sodium) | SINGULAIR
(Merck) |
10mg | tabs | Adults and Children: Take granules by mouth within 15 minutes of opening packet; may dissolve in 5mL of cold or room temperature baby formula or breast milk, or mix in spoonful of soft applesauce, carrots, rice, or ice cream. <6months w/perennial allergic rhinitis or <2yrs w/seasonal allergic rhinitis: not established. 6–23months: one 4mg granule packet. 2–5yrs: one 4mg chew tab or granule packet. 6–14yrs: one 5mg chew tab. ≥15yrs: one 10mg tab. For all: take once daily. |
| SINGULAIR CHEWABLES*
(Merck) |
4mg, 5mg | chew tabs | ||
| SINGULAIR ORAL GRANULES
(Merck) |
4mg/packet | oral granules | ||
| MAST CELL STABILIZER | ||||
| Cromolyn sodium | GASTROCROM
(Meda) |
100mg/5mL | oral concentrate | Adults and Children: Mix contents of amp in water and drink. Take dose 4 times daily at regular intervals, ½ hour before meals and at bedtime; may increase if insufficient response within 2–3 weeks. <2years: usually not recommended; see literature. 2–12years: 100mg. ≥13years: 200mg. All: max 40mg/kg per day; maintain at lowest effective dose. |
| COMBINED ANTIHISTAMINE + SYMPATHOMIMETIC | ||||
| Acrivastine | SEMPREX-D
(Actient) |
8mg | caps | Children: Not recommended.
Adults: 1 cap every 4–6 hours, max 4/day. |
| Pseudoephedrine HCl | 60mg | |||
| Desloratadine | CLARINEX-D 12 HOUR | 2.5mg | ext-rel tabs | Children: Not recommended.
Adults: Swallow whole. 1 tab twice daily. Renal impairment: 1 tab once daily. |
| Pseudoephedrine sulfate | (Merck) | 120mg | ||
| Desloratadine | CLARINEX-D 24 HOUR | 5mg | ext-rel tabs | Children: Not recommended.
Adults: Swallow whole. 1 tab once daily. Renal impairment: 1 tab every other day. |
| Pseudoephedrine sulfate | (Merck) | 240mg | ||
| Fexofenadine HCl | ALLEGRA-D 12 HOUR
(Sanofi Aventis) |
60mg | ext-rel tabs | Children: Not recommended.
Adults: Swallow whole. Take on an empty stomach. 1 tab twice daily. Renal impairment: initially 1 tab once daily. |
| Pseudoephedrine HCl | 120mg | |||
| Fexofenadine HCl | ALLEGRA-D 24 HOUR
(Sanofi Aventis) |
180mg | ext-rel tabs | Children: Not recommended.
Adults: Swallow whole. Take on an empty stomach. 1 tab once daily. Renal insufficiency: not recommended. |
| Pseudoephedrine HCl | 240mg | |||
| NOTES | ||||
|
* = Contains phenylalanine;‡ = Contains alcohol. Δcaps = capsules; ext-rel = extended-release; ODT = orally disintegrating tablets; soln = solution; susp = suspension; tabs = tablets; tabs+ = scored tablets. **Not an inclusive list. Please see drug monograph or visit www.eMPR.com. (Rev. 4/2013) |
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