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RHOPHYLAC
Bleeding disorders
Immune-mediated blood disorders
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Drug Name:

RHOPHYLAC Rx

Generic Name and Formulations:
Rho (D) immune globulin human 1500 IU (300mcg)/2mL; syringe; for IV or IM inj; preservative- and latex-free; contains albumin (human); solvent/detergent treated.

Company:
CSL Behring, LLC

e-Prescribe this drug via Surescripts

Therapeutic Use:

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Indications for RHOPHYLAC:

Raising platelet counts in Rho (D) positive non-splenectomized patients with chronic immune thrombocytopenic purpura (ITP).

Adult Dose for RHOPHYLAC:

See literature. 250 IU (50mcg) per kg by IV only at rate of 2mL per 15–60 seconds.

Children's Dose for RHOPHYLAC:

Not recommended.

Contraindications:

Rho (D) positive patients. IgA deficiency.

Warnings/Precautions:

Monitor patients 20 minutes after administration. Pregnancy (Cat.C).

Interactions:

Do not give live vaccines within 3 months.

Adverse Reactions:

Local or infusion reactions, fever, chills, headache; see literature.

How Supplied:

Single-dose prefilled syringes—1, 10

Indications for RHOPHYLAC:

Suppression of Rh isoimmunization in non-sensitized Rho (D) negative women during pregnancy and in appropriate obstetrical conditions, unless the fetus or father is known to be Rho (D) negative. Suppression of Rh isoimmunization in Rho (D) negative individuals transfused with Rho (D) positive blood products.

Adult Dose for RHOPHYLAC:

See literature. Pregnancy (28–30 weeks gestation), postpartum prevention (within 72 hours), obstetric complications, invasive procedures during pregnancy: 1500 IU (300mcg). Incompatible transfusions (within 72 hours): 100 IU (20mcg) per 2mL transfused blood or per 1mL erythrocyte concentrate.

Children's Dose for RHOPHYLAC:

Not recommended.

Contraindications:

Rho (D) positive patients. IgA deficiency.

Warnings/Precautions:

Monitor patients 20 minutes after administration. Pregnancy (Cat.C).

Interactions:

Do not give live vaccines within 3 months.

Adverse Reactions:

Local or infusion reactions, fever, chills, headache; see literature.

How Supplied:

Single-dose prefilled syringes—1, 10