REVIA Rx

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REVIA

Addiction/dependence
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Generic Name and Formulations:

Naltrexone HCl 50mg; scored tabs.

Select therapeutic use:

Indications for REVIA:

Adjunct in treatment of alcohol or narcotic dependence.

Adult:

Confirm 7–10 day opioid-free period, if questionable do Narcan challenge test (see literature). ≥18yrs: Alcoholism: 50mg daily. Narcotic dependence: Initially 25mg, if no withdrawal symptoms increase to 50mg daily; alternative dosing schedules: see literature.

Children:

<18yrs: not recommended.

Contraindications:

Concomitant opioids, current opioid dependence, or acute opioid withdrawal. Failed Narcan challenge test or (+) urine screen for opioids. Acute hepatitis. Liver failure.

Warnings/Precautions:

Liver disease. Monitor liver function. Warn patients of danger of attempting to overcome opiate blockade. Severe renal dysfunction. Possible acute abstinence syndrome. Depression. Suicidal ideation. Pregnancy (Cat.C). Nursing mothers.

Pharmacological Class:

Opioid antagonist.

Interactions:

Thioridazine increases sedation. Antagonizes opioids (eg, antitussives, antidiarrheals, analgesics). Disulfiram.

Adverse Reactions:

Hepatotoxicity, withdrawal reactions; others, see literature.

How Supplied:

Tabs—30, 100