ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

REVATIO INJECTION
Pulmonary hypertension
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

REVATIO INJECTION Rx

Generic Name and Formulations:
Sildenafil 10mg/vial; soln for IV inj.

Company:
Pfizer Inc.

e-Prescribe this drug via Surescripts


Therapeutic Use:

Product Resources »
  • Product Information
  • Coupons, Samples & Vouchers
  • Patient Education and Assistance

Indications for REVATIO INJECTION:

Pulmonary arterial hypertension (PAH) (WHO Group I) to improve exercise ability and delay clinical worsening, in patients who are temporarily unable to take oral Revatio.

Adult Dose for REVATIO INJECTION:

Give by IV bolus inj. 10mg 3 times daily.

Children's Dose for REVATIO INJECTION:

Not recommended.

See Also:

REVATIO

Pharmacological Class:

Phosphodiesterase type 5 inhibitor (cGMP-specific).

Contraindications:

Concomitant organic nitrates.

Warnings/Precautions:

Pulmonary veno-occlusive disease: not recommended. PAH secondary to sickle cell anemia. Underlying conditions that could be affected by vasodilatory effects (eg, concomitant antihypertensive therapy, BP<90/50, fluid depletion, severe left ventricular outflow obstruction, autonomic dysfunction). Retinitis pigmentosa. Anatomical penile deformation. Predisposition to priapism. Severe renal or hepatic impairment. Active peptic ulcer. Bleeding disorders. Elderly. Pregnancy (Cat.B). Nursing mothers.

Interactions:

See Contraindications. Hypotension with nitrates. Concomitant potent CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir): not recommended. Potentiated by inhibitors of CY3A4 or CYP2C9, or cimetidine; may need dose adjustment. Antagonized by CYP3A4 inducers (eg, rifampin), bosentan; may need to adjust dose. Concomitant α-blockers (eg, doxazosin) may cause symptomatic hypotension (monitor BP). Potentiates bleeding risk with Vit. K antagonists. Concomitant Viagra or other PDE5 inhibitors: not recommended.

Adverse Reactions:

Epistaxis, headache, GI upset, flushing, insomnia, erythema, dyspnea worsened, rhinitis, sinusitis, myalgia, pyrexia, paresthesia; hypotension, vision or hearing loss, priapism.

Metabolism:

Hepatic (CYP3A, CYP2C9).

Elimination:

Fecal (primary), renal.

Generic Availability:

Tabs (YES); Inj (NO)

How Supplied:

Tabs—90
Single-use vial—1

Sign Up for Free e-newsletters