RENACIDIN IRRIGATION Rx

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RENACIDIN IRRIGATION

Miscellaneous urogenital disorders
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Generic Name and Formulations:

Citric acid 6.602g, glucono-delta-lactone 198mg, magnesium carbonate 3.177g; per 100mL; irrigation soln (pH 3.85).

Company:

Guardian Labs

Select therapeutic use:

Indications for RENACIDIN IRRIGATION:

Dissolution of renal or bladder calculi composed of apatite or struvite in select patients. Adjunct to dissolve apatite or struvite calculi after surgery or to achieve partial dissolution prior to surgical removal. Prevention of incrustations of indwelling urinary tract catheters.

Adult:

Renal calculi: Irrigate with sterile saline at 60mL/hr after fourth or fifth post-operative day and increase until pain, elevated pressure or a maximum of 120mL/hr is achieved; then start Renacidin at max rate achieved with saline. Bladder calculi: 30mL through urinary catheter into bladder, clamp for 30–60 minutes, drain bladder; repeat 4–6 times a day. Catheter incrustation: 30mL through catheter, clamp for 10 minutes, drain; repeat 3 times daily.

Contraindications:

UTIs (obtain urine culture prior to use). Urinary tract extravasation.

Warnings/Precautions:

Monitor magnesium, phosphate, serum creatinine, intrapelvic pressure, and for UTI or catheter obstruction; discontinue if these increase or severe urothelial edema on X-ray occur. Impaired renal function. Maintain catheter patency. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Concomitant magnesium: not recommended.

Pharmacological Class:

Irrigation solution.

Adverse Reactions:

Transient flank pain, urthelial ulceration and/or edema, fever, UTI, back pain, dysuria, transient hematuria, nausea, hypermagnesemia, hyperphosphatemia, elevated serum creatinine, candidiasis, bladder irritation.

How Supplied:

Containers (500mL)—6