Pyschiatric Disorders

Novel Therapy for Major Depressive Disorder Gets Breakthrough Designation

By February 08, 2018

The Breakthrough Therapy designation is intended to offer a potentially expedited development path and review for promising drug candidates.

Written Exposure Therapy Found to Be Effective for PTSD

January 24, 2018

The 24-week assessment showed the largest difference between treatments. The WET group had significantly fewer dropouts than the CPT group (4 versus 25).

Significant Links Between Depressive Symptoms and Mortality in CA Patients

January 23, 2018

The researchers found that greater depressive symptoms were associated with significantly shorter survival (hazard ratio, 0.868; P<0.001), higher rates of chemoradiation interruption (odds ratio, 0.865; P=0.010).

Study Reveals Why Women Leave Medicine More Often Than Men

January 05, 2018

More women are entering medical school but still there are more male doctors.

Vraylar Approved as Maintenance Treatment for Schizophrenia

By November 13, 2017

Results showed that cariprazine significantly delayed the time to relapse compared to placebo (P=0.0010). A total of 49.5% (n=49/99) of placebo treated patients relapsed vs. 29.7% (n=30/101) for the cariprazine treated patients.

Psychosocial Intervention Improves Antidepressant Adherence

September 28, 2017

"The Treatment Initiation and Participation Program is an effective intervention to improve early adherence to pharmacotherapy," the authors write. "Improved adherence can promote improvement in depression."

Treatment Shows Efficacy in Binge Eating Disorder

August 04, 2017

In both studies, more participants on LDX versus placebo were categorized as improved on the Clinical Global Impressions-Improvement starting at week one.

More Sleep May Help Stave off Alzheimer's in Those At Risk

July 07, 2017

The researchers found an association between greater AD pathology and worse subjective sleep quality, more sleep problems, and daytime somnolence.

From Treatment to Training: 5 Uses of Virtual Reality in Healthcare

June 27, 2017

Virtual reality is much more than just a new form of entertainment, it is increasingly being used in a wide range of medical applications.

FDA Fast Tracks Drug for Hallucinations Disorder in Lewy Body Dementia

By June 19, 2017

Nelotanserin is a novel once-daily oral 5HT2A inverse agonist. The 5HT2A receptor has been associated with neuropsychiatric effects, including visual hallucinations.

Risks Associated with Lithium Use in Pregnancy Reevaluated

June 09, 2017

The study included information on 1,325,563 women enrolled in Medicaid. They gave birth between 2000 and 2010.

Antidepressant Linked to Accelerated Bone Loss

June 06, 2017

The researchers found that during venlafaxine treatment there was an increase in CTX and a decrease in P1NP, which was consistent with accelerated bone loss.

Depression Gender Disparities May Emerge Earlier Than Previously Thought

May 04, 2017

The study found the gender gap appears 2 to 3 years earlier than previously thought, from 13 to 15 down to age 12.

Chlorpromazine Dose-Response Investigated for Schizophrenia

By April 13, 2017

The gradual trend toward recommending lower dosages of chlorpromazine has arisen not due to trial based evidence, but rather clinical experience and consensus.

Overactive Bladder Tx Tied to Depressive Disorders

April 13, 2017

The researchers followed over 10,000 women for 3 years to assess the risk of depressive disorders associated with antimuscarinics.

Overactive Bladder Tx Tied to Depression in Women

By April 06, 2017

The researchers hypothesized that some antimuscarinics with "high lipophilicity, neutral polarity, or low molecular size still cross the blood-brain barrier and further affect neurotransmission in the brain," which could possibly trigger the depressive symptoms.

How Likely Are Teens to Seek Treatment for Eating Disorders?

March 27, 2017

Adolescents who met criteria for anorexia nervosa or bulimia nervosa were 2.4 and 1.9 times, respectively, more likely to seek treatment than adolescents who met criteria for binge-eating disorder.

Valbenazine for Tardive Dyskinesia

By March 21, 2017

Hauser, Robert A. et al. "KINECT 3: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial of Valbenazine for Tardive Dyskinesia"

Genetic Testing Abused by Patient with Factitious Disorder

By March 08, 2017

The patient presented with complaints of increased muscle tone in her back muscles and the right side of her body starting in adolescence.

Concussion Frequency, Symptoms Differ Between the Genders

March 03, 2017

Female athletes appear to be more likely than males to suffer concussions during their careers on the field, according to a new study by researchers at Columbia University, New York.

Report Outlines Screening and Treating Pediatric Sexual Assault

February 28, 2017

Pediatricians should be comfortable with treating and screening for sexual assault, and they should know where to send their teenage patients for any additional help, according to a clinical report from the American Academy of Pediatrics (AAP) published online in Pediatrics.

AAP: New Laws Do Not Denote Marijuana Use as Benign

February 28, 2017

The American Academy of Pediatrics (AAP) has published guidance to challenge any perception that marijuana is safe, even as 29 states allow its use.

Lurasidone Effective in Phase 3 Pediatric Bipolar Depression Study

By February 27, 2017

Sunovion announced that its Phase 3 study of Latuda (lurasidone HCI) in children aged 10 to 17 years with bipolar depression met its primary and secondary endpoints.

Gestational Diabetes Mellitus and Postpartum Depression: What's The Link?

January 24, 2017

Gestational diabetes mellitus (GDM) may increase a first-time mother's risk of postpartum depression, and a history of maternal depression along with GDM further increases that risk, according to a study published online in Depression and Anxiety.

Generic Narcolepsy Drug Approved with Strict Safety Controls

By January 18, 2017

The Food and Drug Administration (FDA) has approved Sodium Oxybate Oral Solution, the first generic version of Jazz's Xyrem Oral Solution.

Antipsychotic Use Among COPD Patients May Up ARF Risk

By January 06, 2017

According to a study published in JAMA Psychiatry, the use of antipsychotics was associated with an increased risk of acute respiratory failure in patients with chronic obstructive pulmonary disease (COPD).

Survey Offers Glimpse of Mental Health Among Airline Pilots

December 16, 2016

More than one-tenth of professional airline pilots may suffer from depression, according to research published online in Environmental Health.

Link Between Falls and High-Risk Medications Investigated

November 29, 2016

Older fallers have often been administered high-risk medications, frequently at higher-than-recommended doses, according to a study published online November 28 in the Journal of the American Geriatrics Society.

Comorbid Risks of Acute Kidney Injury Examined in Critically Ill

November 28, 2016

For critically ill adults, acute kidney injury is a risk factor for delirium and coma, according to a study published online in the American Journal of Respiratory and Critical Care Medicine.

Sugary Drinks and Sleep: What's the Link?

November 11, 2016

Improving sleep may help reduce an individual's sugar-sweetened, caffeinated beverage intake, and vice-versa, according to a study published online in Sleep Health.