Psychosis

Neonatal Drug Withdrawal Risk Up with In Utero Exposure to Opioids, Psychotropics

August 03, 2017

The researchers observed variation in the absolute risk for neonatal drug withdrawal from 1.0 to 11.4% for infants exposed in utero to prescription opioids alone and opioids co-prescribed with gabapentin, respectively.

Large Number of Opioid Rxs Written for Patients with Mental Illness

July 10, 2017

Those with psychological conditions more likely to overdose or have other problems tied to opioid use

Tablet-Related Issue Prompts Recall of Antipsychotic Agent

By June 15, 2017

If two or more consecutive doses include the affected product, therapeutic levels may not be maintained and may result in a resurgence of symptoms.

Antipsychotic Efficacy Compared in Real-World Schizophrenia Study

June 09, 2017

Risk of rehospitalization substantially lower with long-acting injectables versus oral equivalents

Two-Month Dosing Option Approved for Aristada in Schizophrenia

By June 06, 2017

The new dosing option allows patients with schizophrenia to treat their symptoms with just 6 injections per year

Study Examines Frequency of Postmarket Safety Events Among New Drugs

By May 09, 2017

Analysis showed that safety events were significantly more frequent among biologics, psychiatric treatments, treatments with accelerated approval, and near-regulatory deadline approval.

Treatment Adherence in Schizophrenia: Which Antipsychotic Is Best?

By April 20, 2017

According to the adjusted results from a recent study, second generation antipsychotic long-acting injectable medications were linked to consistently more adherence and persistence when compared to oral antipsychotic patients.

Chlorpromazine Dose-Response Investigated for Schizophrenia

By April 13, 2017

The gradual trend toward recommending lower dosages of chlorpromazine has arisen not due to trial based evidence, but rather clinical experience and consensus.

Do Psychiatric Disorders Correlate With Future Risk of Alzheimer's?

April 11, 2017

We examined whether mental and behavioral disorders in general or specific mental and behavioral disorder categories increase the risk of Alzheimer's disease.

Certain Antipsychotics May Up CV Risk in Older Patients

By April 11, 2017

Researchers assessed whether therapy with high-risks of metabolic side effects increase the risk of major cardiovascular events.

Borderline Personality Disorder: How Effective are Psychotherapies?

By April 10, 2017

Results showed that the investigated psychotherapies were moderately more effective—as assessed by standardized mean differences (Hedges g)—in terms of borderline symptoms, self-harm and suicide than control interventions.

Risperidone vs. Olanzapine for Persistent Delusional Disorder

By April 09, 2017

The review found no statistically significant difference between the two groups regarding adherence and treatment response.

Genetic Testing Abused by Patient with Factitious Disorder

By March 08, 2017

The patient presented with complaints of increased muscle tone in her back muscles and the right side of her body starting in adolescence.

FDA to Review Vraylar for Maintenance Treatment of Schizophrenia

By March 08, 2017

Allergan announced that the Food and Drug Administration (FDA) has accepted the supplemental New Drug Application (sNDA) for Vraylar (cariprazine) for the addition of new data evaluating Vraylar for the maintenance of efficacy in adults with schizophrenia.

Mental Health Tx Rejection Greater When Only Meds Used

March 07, 2017

A total of 186 studies of patients who sought help for mental health conditions were analyzed, overall, the average treatment refusal rate was 8.2%.

New Warning Added to Antipsychotic Drug Labeling

By February 27, 2017

The FDA has approved updates to all antipsychotic medication labels to specifically warn of somnolence, postural hypotension, and motor and sensory instability risks.

Adverse Events Related to Antipsychotic Use Assessed in Hospitalized Seniors

February 15, 2017

However, greater use of brain imaging associated with atypical APMs after cardiac surgery in seniors

Prescriptions for Risky Drug Combinations on the Rise Among Seniors

February 14, 2017

Between 2004 and 2013 the number of polypharmacy outpatients visits by adults over 65 years almost doubled.

Latuda OK'd for Use in Adolescents with Schizophrenia

By January 30, 2017

Sunovion announced that the Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for Latuda (lurasidone HCl) for the treatment of schizophrenia in adolescents aged 13-17 years.

MAPS Looks to Make MDMA into an FDA-Approved Psychotropic Agent

By January 26, 2017

Based on Phase 2 studies, 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy could be a potential treatment option for several psychiatric conditions, however turning this controlled substance into a therapeutic agent is contingent upon successful Phase 3 trials and regulatory approval.

Antipsychotic Use Among COPD Patients May Up ARF Risk

By January 06, 2017

According to a study published in JAMA Psychiatry, the use of antipsychotics was associated with an increased risk of acute respiratory failure in patients with chronic obstructive pulmonary disease (COPD).

Full Launch of Clozapine REMS Program Postponed

By December 19, 2016

The Food and Drug Administration (FDA) has announced that the full launch for the Clozapine Risk Evaluation and Mitigation Strategy (REMS) program will be postponed due to recent technical and logistical challenges.

FDA: Boxed Warning Removed from Smoking Cessation Treatment

By December 19, 2016

The FDA determined the benefits of this smoking cessation therapy outweighed the potential risks.

Study: The 10 Most Frequently Used Psychiatric Drugs in the U.S.

December 13, 2016

One in six U.S. adults take a psychiatric medication to treat conditions such as depression, anxiety, and insomnia, according to a study published online in JAMA Internal Medicine.

Survey Reveals Many Teens Still Participate in Dangerous 'Choking Game'

November 22, 2016

About 4% of U.S. teens surveyed admit to trying the "choking game," a potentially deadly game of temporary strangulation, and young people who play the game alone are much more likely to harbor thoughts of suicide

Drug Choice for Acute Agitation May Affect Psychiatric ED Length of Stay

By November 17, 2016

Patients who had repeated use of intramuscular (IM) antipsychotics experienced a significantly longer length of stay (LOS) in the emergency department (ED) vs. non-repeat users of IM antipsychotics, according to a new study published in Journal of Psychiatric Practice.

Efficacy of Lurasidone Assessed in Adolescent Schizophrenia Patients

By October 27, 2016

Sunovion has announced positive results from a study evaluating Latuda (lurasidone HCI) for the treatment of schizophrenia in adolescents aged 13 to 17 years old.

Elevated Heart Rate, BP Linked to Psych Disorders Later in Life

October 27, 2016

Young men with a resting heart rate and blood pressure that are elevated - but still within normal range - appear more likely to develop a wide range of mental illnesses later in their lives, according to a study published online in JAMA Psychiatry.