Psychiatric Disorders

Oxytocin Levels and Lack of Emotional Awareness May Be Linked

December 13, 2017

The researchers found that most measures of social-emotional functioning showed impairment in women with AN or a history of AN, versus those with no eating disorder history.

Paternal SSRI Use Before Conception Linked to Offspring ADHD

December 11, 2017

After adjustment for potential confounders, exposed children had a 26% increased risk of ADHD compared with unexposed children.

Certain Drug Classes Tied to Less Frequent Driving Impairment Warnings

By December 01, 2017

More than two-thirds (85%) of those on sedatives and narcotics reported being counseled by a provider on the possibility of impaired driving.

Are Network Characteristics Prognostic for Long-Term Outcomes in Depression?

December 01, 2017

The researchers found that good responders had higher mean MFQ summary scores at baseline and higher mean levels of suicidality than poor responders.

Is AVATAR Therapy a Viable Treatment for Auditory Hallucinations?

November 27, 2017

The researchers found that 83% of participants met the primary outcome of reduction in auditory verbal hallucinations at 12 weeks, as measured by the total score on the Psychotic Symptoms Rating Scales Auditory Hallucinations (PSYRATS-AH).

Physician Burnout Associated With Significant Financial Costs

November 22, 2017

Economic loss at Stanford over two years expected to range from 15.5 million to 55.5 million

FDA Grants Fast Track Status to Lumateperone for Schizophrenia

By November 20, 2017

In two studies, lumateperone showed a statistically significant separation from placebo on the primary endpoint, the Positive and Negative Syndrome Scale, or PANSS, total score.

Impact of Psoriasis Treatments on Depressive Symptoms Examined

By November 20, 2017

Psoriasis patients may be at increased risk for depression and suicidality.

Impact of Peer Review PA on Child Atypical Antipsychotic Use

November 16, 2017

Researchers used Medicaid administrative claims data from 4 geographically diverse states to examine the impact of peer review PA policies on AAP use among Medicaid-insured youth.

Psychostimulant Use Linked to Preeclampsia, Preterm Birth

November 15, 2017

Small increased relative risk of preeclampsia, preterm birth; absolute risk increases are small

FDA Approves Antipsychotic Agent With Sensor to Track Ingestion

By November 14, 2017

The product is approved for the treatment of schizophrenia, acute treatment of manic and mixed episodes associated with bipolar I disorder and for use as an add-on treatment for depression in adults.

Long-Term Effects of Valbenazine Examined in Adults With Tardive Dyskinesia

By November 14, 2017

Maintenance of treatment effect was demonstrated with both doses.

Maternal Use of ADHD Meds Linked to Neonatal Morbidity

November 13, 2017

Increased risk of neonatal morbidity, especially central nervous system-related disorders

Does Continuing Lithium Tx in CKD Patients Up the Risk of End-Stage CKD?

By November 10, 2017

In the subcohorts of patients with a diagnosis of bipolar disorder, continuing lithium was associated with decreased end-stage CKD, whereas continuing anticonvulsants was not.

Positive Results for Brexanolone in Postpartum Depression Trials

By November 10, 2017

The Hummingbird Phase 3 program included two Phase 3, multicenter, randomized, double-blind, parallel-group, placebo-controlled trials designed to evaluate the safety and effectiveness of brexanolone in women with moderate and severe PPD.

Routine Hypertension Monitoring May Be Necessary With Some Antipsychotics

By November 10, 2017

Antipsychotics used to treat disorders such as schizophrenia, bipolar disorder, and other psychoses mainly involve D2 receptor antagonism and some newer agents target D4 antagonism.

CPAP vs. Gastric Band for Severe Sleep Apnea

November 09, 2017

The researchers found that LGB was associated with a greater drop in BMI. In intention-to-treat analyses, the effective apnea-hypopnea index (AHI) at nine months was 29.5 and 20 events/hour in the LGB and CPAP groups, respectively (P=0.02), while at 18 months, the effective AHI was 20.9 and 21.4 events/hour, respectively.

How Computerized CBT May Aid Depression, Anxiety

November 09, 2017

Completing more CCBT sessions was correlated with greater effect size improvements in mental health-related quality of life and symptoms.

Omega-3 Supplementation Linked to Improved Executive Functioning

By November 08, 2017

In children with mood disorders, Ω3 supplementation was found to decrease impairment in executive function.

Sertraline May Not Benefit Non-Dialysis Dependent CKD Patients With MDD

November 07, 2017

The researchers found that there was a change in the 16-item Quick Inventory of Depression Symptomatology-Clinician Rated of −4.1 in the sertraline group and −4.2 in the placebo group.

Recall: Syringes Labeled for Sedation Med Instead Contain Antiemetic

By November 06, 2017

Dose-dependent serious cardiac arrhythmias may be observed with higher dosages of ondansetron in those patients with certain pre-existing cardiac conditions.

Depression Examined During Physician's Internship Year

October 31, 2017

Researchers conducted a prospective longitudinal cohort study of medical internship in the United States in which 3,121 interns (49.7% women) were recruited across all specialties from 44 medical institutions.

Acetaminophen Use During Pregnancy Linked to Offspring ADHD

By October 30, 2017

Results showed that after adjusting for maternal use of acetaminophen pre-pregnancy, familial risk and indications of acetaminophen use, the hazard ratio (HR) of ADHD with ≥29 days of acetaminophen use was 2.20 (95% CI; 1.50-3.24).

Prevalence of Nonmedical Amphetamine Use May Be Underreported

October 27, 2017

Researchers analyzed prevalence and correlates of discordant responses among past-year Adderall users, defined as reporting past-year nonmedical Adderall use but not past-year nonmedical amphetamine use.

Valbenazine Granted Orphan Drug Designation for Tourette Syndrome

By October 25, 2017

Valbenazine is already approved and marketed as Ingrezza in the US to treat adults with tardive dyskinesia

Non-Invasive 'Neuro-Laser' Found to Be Effective for Depression

By October 23, 2017

Results showed that 36 of the 39 participants experienced "a robust response" (decrease of QIDS total score by ≥50%) after 16.82 ± 6.26 treatments.

HBOT Linked to Significant Reduction in PTSD Symptoms

By October 20, 2017

Following completion of all treatments 12 (52%) of the 23 subjects who initially met PTSD Checklist-Military (PCL-M) for diagnosis no longer met the threshold criteria.

Opinion: How Clinicians Can Help Reduce Firearm-Related Violence

October 18, 2017

Making a public commitment is encouraged as a positive action that physicians can take.

Psychotropic Drug Indications

October 16, 2017

A comparative list of psychotropic medications with their mood disorder indications (bipolar disorder, major depressive disorder, treatment resistant depression, premenstrual dysphoric disorder, and others).

AASM: Position Statement on Home Sleep Apnea Testing

By October 16, 2017

HSATs are ordered by healthcare providers to help diagnosis obstructive sleep apnea (OSA) in adults.