These results challenge existing conceptions that omega-3 fatty acids may be effective in treating adolescent major depressive disorder.
Results showed that discontinuation of any SNRI was associated with withdrawal symptoms, with the highest prevalence linked to venlafaxine and desvenlafaxine.
There was a correlation for high-frequency engagement in each additional digital media activity at baseline with a significantly increased odds of having ADHD symptoms across follow-up (odds ratio, 1.11).
The labeling changes are based on a review of postmarketing adverse event reports found in the FDA Adverse Event Reporting System (FAERS) database and published medical literature.
The recall affects approximately 470,000 units that include drugs packaged with 3 to 10 tablets per blister card. The blister packs were developed for use in hospitals, however some were sent to retail pharmacies and were likely dispensed for in-home use.
The retrospective cohort study involved a search of Medicaid claims of pediatric patients aged 5 to 20 years who were initiated on atypical antipsychotic medications.
Prior to this approval, the Aristada initiation regimen consisted of taking oral aripiprazole for 21 consecutive days starting with the first Aristada dose.
Nuplazid, a non-dopaminergic, selective serotonin inverse agonist, targets 5-HT2A receptors that are thought to be involved in Parkinson's disease psychosis.
The correlation between gestational age at birth and symptoms of ADHD in preschool and school-age children was compared after adjustment for unmeasured genetic and environmental risk factors.
The researchers found that depression or suicidal ideation did not differ at baseline for patients ever exposed to efavirenz versus those never exposed to efavirenz and receiving nevirapine.
The highest risk of overdose was seen on the first days of concurrent opioid and benzodiazepine use, with a decrease in risk over time.
A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.
Compared with the reference group, lithium-exposed pregnancies had an increased risk for neonatal readmission (27.5 vs 14.3%; pooled adjusted odds ratio, 1.62).
These correlations were similar in size to the autoregressive link between PS from ages 15 to 16. There was a statistically significant association for PS at age 15 years with cannabis use at age 16 years.
In this cross-sectional study, the use of medications with depression as an adverse effect was associated with a higher prevalence of depression while a similar association was not observed for medications without depression as a possible side effect.
For decades the AMA has demonstrated leadership on this issue, recommending common-sense gun safety precautions, waiting periods and background checks for those wishing to purchase a gun, and increased mental health service funding.
The researchers found that from baseline to week 12, the dual-energy X-ray absorptiometry percentage total body fat increased by 1.18, 4.12, and 1.66% for risperidone, olanzapine, and aripiprazole, respectively, and was significantly greater for olanzapine than risperidone or aripiprazole.
Over 1 year, subjects who were recruited and corroborated as good sleepers were monitored with daily sleep diaries. Regular assessments of participants' daytime function, stress and life events, and medical and mental health were made.
The APA is highlighting the need for more funding for evidence-based treatment and its dissemination, including crisis services, as well as more research focused on risk assessment, evidence-based prevention programs, and treatment to reduce the incidence of suicide.
The researchers found that job strain was associated with an almost 50% increased risk of atrial fibrillation (hazard ratio [HR], 1.48; 95% confidence interval, 1.00 to 2.18) after adjustment for age, sex, and education.
The researchers found that 11 of 20 studies that reported estimates for ASD (777,518 participants) found higher odds with HDP (adjusted odds ratio [aOR], 1.35) in pooled analysis. For the 6 studies reporting adjusted estimates of ADHD (1,395,605 participants), the pooled adjusted OR was 1.29.
The number of medications used with depression as a possible adverse effect correlated with increased prevalence of concurrent depression, in analyses excluding antidepressant users.
Using data from the National Vital Statistics System, the CDC researchers examined trends in age-adjusted suicide rates in individuals 10 years of age and older, by state and sex, across 6 consecutive 3-year periods (1999-2016).
This relationship was bidirectional, with men who reported worse distress also subsequently reporting worse urinary, bowel, and sexual functions.
One recent survey found that 42% of US physicians are burned out, with rates of 38% among men and 48% among women. The authors here suggest that clinicians are encouraged to care for human beings, not merely to manage health information.