PROZAC WEEKLY
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PROZAC WEEKLY to:
Generic Name for PROZAC WEEKLY
Fluoxetine (as HCl) 90mg; caps containing e-c delayed-release pellets.
Legal Classification:
Rx
Pharmacological Class for PROZAC WEEKLY
SSRI.
Manufacturer of PROZAC WEEKLY
Dista Products Company
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Indications for PROZAC WEEKLY
Maintenance phase of depression.
Adult dose for PROZAC WEEKLY
90mg once weekly. Start 7 days after last dose of fluoxetine 20mg (when switching from daily dosing).
Children's dosing for PROZAC WEEKLY
Not recommended.
Also:
Contraindications for PROZAC WEEKLY
During or within 14 days of MAOIs. Concomitant pimozide, thioridazine (may cause QTc prolongation).
Warnings/Precautions for PROZAC WEEKLY
Monitor for serotonin syndrome or neuroleptic malignant syndrome-like signs/symptoms; discontinue if occurs. Discontinue if unexplained allergic reaction occurs. Renal or hepatic dysfunction. History of seizures or mania/hypomania. Recent MI. Unstable heart disease. ECT (prolonged seizures). Reevaluate periodically in long-term use. Avoid abrupt cessation. Monitor weight. Conditions that affect metabolism or hemodynamic responses. Volume depletion. Diabetes. Suicidal tendencies (monitor). Write ℞ for smallest practical amount. Elderly. Labor & delivery. Pregnancy (Cat.C; avoid 3rd trimester or consider lower dose; see literature for effects on neonate). Nursing mothers: not recommended.
Interactions for PROZAC WEEKLY
See Contraindications. Do not start MAOI or thioridazine within at least 5 weeks of discontinuing fluoxetine. Concomitant SSRIs, SNRIs, tryptophan: not recommended. May potentiate protein-bound drugs (eg, warfarin, digoxin) and those metabolized by CYP2D6 (eg, tricyclics, vinblastine, flecainide). May potentiate carbamazepine, phenytoin. Monitor lithium, phenytoin, warfarin, tricyclics. Caution with benzodiazepines (eg, diazepam, alprazolam), antipsychotics (eg, clozapine, haloperidol), other CNS drugs. Increased risk of bleeding with NSAIDs, aspirin, warfarin, others that affect coagulation. Caution with triptans, linezolid, lithium, tramadol, St. John's wort; may cause serotonin syndrome (eg, weakness, incoordination, hyperreflexia). Hyponatremia with diuretics.
Adverse Reactions for PROZAC WEEKLY
Nausea, CNS stimulation (eg, anxiety, nervousness, insomnia), somnolence, headache, mania/hypomania, anorexia, weight loss, tremor, asthenia, sexual dysfunction, sweating, GI disturbances, respiratory symptoms, motor impairment, serum sickness, hypo- or hyperglycemia, rash (may be serious), urticaria, pruritus; rarely: platelet dysfunction. Children: thirst, hyperkinesia, agitation, personality disorder, epistaxis, urinary frequency, menorrhagia.
How is PROZAC WEEKLY supplied?
Caps 10mg—100
20mg—30, 100, 2000
40mg—30
Liq—4oz
Weekly—4
Related Disease:
Depression