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Miscellaneous dermatological conditions
Only 4 drugs may be compared at once

Generic Name and Formulations:

Tacrolimus 0.03%, 0.1%; oint.

Select therapeutic use:

Indications for PROTOPIC:

Second-line therapy: for short-term and non-continuous chronic treatment of moderate-to-severe atopic dermatitis in non-immunocompromised patients when other topical therapies are inadvisable or ineffective.

Adults and Children:

<2yrs: not recommended. 2–15yrs: use 0.03% strength. ≥16yrs: use either strength. Apply to affected areas twice daily. Do not occlude or apply to wet skin.


Avoid continuous long-term use in any age group. Clear infection at treatment site first if present. Netherton's syndrome, generalized erythroderma, malignant or pre-malignant skin conditions: not recommended. Immunocompromised. Varicella zoster. Herpes simplex. Eczema herpeticum. Consider discontinuing if lymphadenopathy of unknown etiology or acute infectious mononucleosis develops. Avoid sun, UV light. Reevaluate if no improvement after 6 weeks. Renal impairment. Pregnancy (Cat.C). Nursing mothers: not recommended.


Caution with CYP3A4 inhibitors in widespread and/or erythrodermic disease.

Pharmacological Class:


Adverse Reactions:

Local reactions (eg, burning, pruritus, rash, folliculitis, acne, tingling, hyperesthesia, cysts), headache, flu symptoms, sinusitis, alcohol intolerance, back pain, varicella or herpes zoster, dyspepsia, myalgia; rare: malignancy (eg, skin, lymphoma).

Generic Availability:


How Supplied:

Oint—30g, 60g, 100g

PROTOPIC 30g of 0.03% tube of ointments (Qty:1)

appx. price $270.00