PROTONIX TABLETS

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Generic Name for PROTONIX TABLETS

Pantoprazole (as sodium) 20mg, 40mg; e-c delayed-release tabs.

Legal Classification:

Rx

Pharmacological Class for PROTONIX TABLETS

Proton pump inhibitor.

Manufacturer of PROTONIX TABLETS

Wyeth Pharmaceuticals

Indications for PROTONIX TABLETS

Short-term treatment and maintenance of healing of erosive esophagitis (EE), symptomatic GERD. Pathological hypersecretory conditions (eg, Zollinger-Ellison syndrome).

Adult dose for PROTONIX TABLETS

Take 30mins before a meal. Swallow whole. Do not crush or chew granules. Susp: Mix contents of packet in 5mL of apple juice or applesauce (do not mix in water, other liquids or foods); then swallow. May give via NG tube (see literature). Treatment of EE: 40mg once daily for ≤8 weeks; if not healed, may repeat for 8 more weeks. Maintenance of EE healing: 40mg once daily. Pathological hypersecretory conditions: initially 40mg twice daily; max 240mg/day.

Children's dosing for PROTONIX TABLETS

Take 30mins before a meal. Swallow whole. Do not crush or chew granules. Susp: Mix contents of packet in 5mL of apple juice or applesauce (do not mix in water, other liquids or foods); then swallow. May give via NG tube (see literature). <5yrs: not recommended. Treatment of EE: Give once daily for up to 8 weeks. ≥5yrs: (≥15kg to <40kg): 20mg; (≥40kg): 40mg.

Also:

Precautions for PROTONIX TABLETS

Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions for PROTONIX TABLETS

Concomitant atazanavir or nelfinavir: not recommended. May alter absorption of gastric pH-dependent drugs (eg, ketoconazole, iron, ampicillin). Monitor warfarin. May give antacids concomitantly. IV form chelates metal ions. May cause false (+) urine THC test.

Adverse Reactions for PROTONIX TABLETS

Headache, GI upset, dizziness, arthralgia, inj site reactions; also children: upper respiratory infection, fever, rash, abdominal pain; rare: cyanocobalamin deficiency.

How is PROTONIX TABLETS supplied?

Tabs—90
Susp—30 packets/box
Vials (40mg)—1

Related Disease:

GERD {GERD}
Hypersecretory conditions~Zollinger-Ellison syndrome

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