PROCHIEVE Rx

Select the drug indication to add to your list

PROCHIEVE

Infertility
Menopause and HRT
Only 4 drugs may be compared at once

Generic Name and Formulations:

Progesterone (micronized) 4% (45mg/applicatorful), 8% (90mg/applicatorful); vaginal gel; contains mineral oil.

Select therapeutic use:

Indications for PROCHIEVE:

8% strength: Progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency.

Adult:

Supplementation: 1 applicatorful of 8% (90mg) intravaginally once daily. Replacement: 1 applicatorful of 8% (90mg) intravaginally twice daily. If pregnancy occurs, may continue treatment until placental autonomy is achieved (10–12 weeks).

Children:

Not applicable.

Contraindications:

Undiagnosed vaginal bleeding. Breast or genital carcinoma. Liver dysfunction or disease. Missed abortion. Thrombophlebitis or thromboembolic disorders.

Warnings/Precautions:

Conditions aggravated by fluid retention. Depression. Include Pap smear with pretreatment exam. Discontinue if signs of thrombotic disorders (eg, thrombophlebitis, cerebrovascular disorders, pulmonary embolism, retinal thrombosis) occur. Pregnancy: see literature. Nursing mothers.

Interactions:

Allow at least 6 hours between administration of this and other vaginally-administered products.

Adverse Reactions:

Mastodynia, constipation, somnolence, GI upset, headache, abdominal/perineal pain, nervousness, cramps, nocturia, depression, decreased libido, arthralgia, bloating, pain, vaginal candidiasis/discharge, dizziness, dyspareunia, pruritus genital, allergy, fatigue, urinary tract infection, others.

How Supplied:

Prefilled applicators 4%—6
Prefilled applicators 8%—6, 18

Indications for PROCHIEVE:

Secondary amenorrhea.

Adult:

Initially one applicatorful of 4% (45mg) intravaginally every other day up to a total of 6 doses. If inadequate response may give 1 applicatorful of 8% (90mg) intravaginally every other day for a total of 6 doses.

Children:

Not applicable.

Contraindications:

Undiagnosed vaginal bleeding. Breast or genital carcinoma. Liver dysfunction or disease. Missed abortion. Thrombophlebitis or thromboembolic disorders.

Warnings/Precautions:

Conditions aggravated by fluid retention. Depression. Include Pap smear with pretreatment exam. Discontinue if signs of thrombotic disorders (eg, thrombophlebitis, cerebrovascular disorders, pulmonary embolism, retinal thrombosis) occur. Pregnancy: see literature. Nursing mothers.

Interactions:

Allow at least 6 hours between administration of this and other vaginally-administered products.

Adverse Reactions:

Cramps, emotional lability, fatigue, sleep disorders, depression, headache, bloating, vaginal discharge, nausea, changes in appetite, back or abdominal pain, myalgia, pruritus genital, others.

How Supplied:

Prefilled applicators 4%—6
Prefilled applicators 8%—6, 18