PRINIVIL
Generic Name for PRINIVIL
Lisinopril 2.5mg, 5mg+, 10mg, 20mg, 40mg; tabs; +scored.
Legal Classification:
Rx
Pharmacological Class for PRINIVIL
ACE inhibitor.
Manufacturer of PRINIVIL
Merck & Co., Inc.
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Indications for PRINIVIL
Hypertension.
Adult dose for PRINIVIL
Initially and if not on diuretics: 10mg once daily. Usual range: 20–40mg once daily. If on diuretic: suspend diuretic for 2–3 days before starting; resume diuretic if BP not controlled by lisinopril alone. If diuretic cannot be discontinued: initially 5mg daily (supervise 1st dose). CrCl 10–30mL/min: initially 5mg daily; CrCl <10mL/min: initially 2.5mg daily; max 40mg daily.
Children's dosing for PRINIVIL
<6yrs or CrCl <30mL/min/1.73m2: not recommended. ≥6yrs: initially 0.07mg/kg (max 5mg) once daily; usual max 0.61mg/kg (40mg) once daily.
Contraindications for PRINIVIL
History of ACEI-associated or other angioedema. Pregnancy (Cat.D in 2nd and 3rd trimesters).
Precautions for PRINIVIL
Renal impairment. Dialysis (esp. high-flux membrane). Salt/volume depletion. Hypertrophic cardiomyopathy. CHF. Ischemic heart disease. Cerebrovascular disease. Renal artery stenosis. Surgery. Monitor renal function, serum potassium in diabetics. Monitor WBCs in renal and collagen vascular disease patients. Discontinue immediately if angioedema or laryngeal edema occurs (have SC epinephrine available). Elderly. Pregnancy (Cat.C in 1st trimester). Nursing mothers: not recommended.
Interactions for PRINIVIL
May cause hypotension or increased BUN with diuretics, hyperkalemia with K+ sparing diuretics or K+ supplements. May increase lithium levels; monitor frequently. Antagonized by, and increased risk of renal failure with, NSAIDs.
Adverse Reactions for PRINIVIL
Dizziness, headache, fatigue, diarrhea, upper respiratory symptoms, cough, nausea, hyperkalemia, orthostatic hypotension, renal impairment, angioedema; liver dysfunction, blood dyscrasias (rare).
How is PRINIVIL supplied?
Tabs 2.5mg—30, 100
Tabs 5mg—90, 100, 1000
Tabs 10mg, 20mg—30, 90, 100, 1000
Tabs 40mg—100
Related Disease:
Hypertension