PRIMAXIN IM 500
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PRIMAXIN IM 500 to:
Generic Name for PRIMAXIN IM 500
Imipenem 500mg, cilastatin sodium 500mg; IM inj; sodium content 2.8mEq/g imipenem.
Legal Classification:
Rx
Pharmacological Class for PRIMAXIN IM 500
Carbapenem (thienamycin) + dehydropeptidase I inhibitor.
Manufacturer of PRIMAXIN IM 500
Merck & Co., Inc.
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Indications for PRIMAXIN IM 500
Susceptible mild to moderate infections including lower respiratory tract, intraabdominal, skin and skin structure, gynecologic. IM form not for severe or life-threatening infections.
Adult dose for PRIMAXIN IM 500
Base dose on imipenem component. Lower respiratory tract, skin and skin structure, gynecologic: mild to moderate: 500–750mg every 12 hours. Intraabdominal: 750mg every 12 hours. CrCl <20mL/min: not recommended.
Children's dosing for PRIMAXIN IM 500
Not recommended.
Also:
Contraindications for PRIMAXIN IM 500
IM: Allergy to amide-type local anesthetics. Heart block. Severe shock.
Warnings/Precautions for PRIMAXIN IM 500
Penicillin, cephalosporin, or other allergy. CNS disorders (esp. brain lesions or seizures). Renal impairment: reduce dose. Hemodialysis: see literature. GI disease (esp. colitis). IM: prepare with lidocaine (see literature). Pregnancy (Cat.C). Nursing mothers.
Interactions for PRIMAXIN IM 500
Concomitant ganciclovir (increased seizure risk), probenecid: not recommended. May antagonize valproic acid; monitor (consider alternative therapy).
Adverse Reactions for PRIMAXIN IM 500
Local reactions, GI upset, confusion, myoclonia, seizures, changes in serum electrolytes, dizziness, somnolence, anaphylaxis, blood dyscrasias, elevated liver enzymes, fever, rash, hypotension.
How is PRIMAXIN IM 500 supplied?
Vials (IV)—25
Vials (IM)—10
Related Disease:
Infections, bacterial~systemic antiinfectives