Poisoning & Drug Dependence
Results found that all primary endpoints for non-inferiority of extended-release naltrexone group were met; retention in treatment (P=0.04), group proportion of total number of opioid-negative urine drug tests (P<0.001), days of heroin use (P<0.001) and days of other illicit opioids use (P<0.001).
The researchers compared an cohort of patients with psoriasis (≥18 years of age) drawn from several databases to 20 patients without psoriasis who were matched by age, sex, and general practice (n=55,537 and 854,314 respectively).
In the changing legal environment, pediatric physicians must review their approach to screening for marijuana use and discussing the associated health consequences
The Carbon Monoxide Breath Sensor System (COBSS) informs the user how breath carbon monoxide levels are affected by their smoking behavior.
At the pharmacy level, a greater emphasis will be placed on counseling to help patients understand the risks associated with opioid use based on the new Centers for Disease Control and Prevention (CDC) guidelines.
The company reached the decision with an outside Process Authority, who determined that their manufacturing process had the potential to create the deadly toxin botulin.
"the dangers associated with failing to treat an opioid use disorder can outweigh the risks of co-prescribing MAT and benzodiazepines," said FDA Commissioner Scott Gottlieb.
The researchers observed an increase in life expectancy at birth from 2000 to 2015, from 76.8 to 78.8 years.
Results showed that new persistent opioid use, defined as continued opioid prescription fills between 90 and 180 days after the index surgical procedure, were 4.8% compared to 0.1% in the non-procedure control group.
The newly-approved app delivers behavioral therapy that's designed to "increase abstinence from substance abuse and increase retention in outpatient therapy programs," the FDA said.
The patient admitted to taking 2 teaspoons of self-prepared apricot kernel extract along with 3 tablets of Novodalin, an herbal fruit kernel supplement, every day for the past 5 years.
In the United States, Canada, and United Kingdom, physicians do not have the legal duty to assist unless there is a prior patient-physician relationship.
The researchers found that during the first 30 minutes following e-cigarette inhalation with nicotine, there was a significant increase in blood pressure, heart rate and arterial stiffness.
The Food and Drug Administration (FDA) is recommending that patients avoid the concomitant use of sodium polystyrene sulfonate with other oral medications.
Patients were more likely to continue using the opioids if they were initially prescribed medications for a longer time.
To put the scourge of conventional cigarettes in context, smoking kills 15 times more Americans per year than opioids.
Of the 3,945 who had overdosed on prescription opioids, prescriptions decreased from 32.4% before the overdose to 28.3% after. Meanwhile, the number of patients receiving medication-assisted treatment rose from 29.4 to 33.0% after a heroin overdose.
Smoking cessation therapy regimens of prescription drugs and over-the-counter medications used to help patients quit smoking.
The FDA's marketing clearance applies to 13 commonly abused drugs; there are multiple cut-off options available for certain drugs.
Results showed that the mean costs over the next 30 days after ED visits were $1,752, $1,805 and $1,977 for ED-initiated buprenorphine, referral alone and brief intervention with facilitated referral, respectively.
Over the study period, smoking during pregnancy increased significantly among women with MDE (35.9 to 38.4%; P=0.02), while a decreasing trend among women without MDE only approached statistical significance (12.5 to 9.1%; P=0.07).
Among the areas likely to benefit from increased funding are treatment centers, with the White House panel recommending rules be waived so that Medicaid recipients can get treatment for their addictions.
In light of the plethora of street names used to refer to a number of drugs, the DEA has issued a comprehensive list for common drugs.
Over 19,569 person-years of follow-up, the adjusted hazard ratios for death from hypertension among marijuana users was 3.42 (95% confidence interval, 1.20 to 9.79).