Poisoning & Drug Dependence

One-Step Drug Test Cup Gains FDA Clearance for OTC Use

By August 16, 2017

The FDA's marketing clearance applies to 13 commonly abused drugs; there are multiple cut-off options available for certain drugs.

Is ED-Initiated Buprenorphine for Opioid Dependence Cost Effective?

By August 16, 2017

Results showed that the mean costs over the next 30 days after ED visits were $1,752, $1,805 and $1,977 for ED-initiated buprenorphine, referral alone and brief intervention with facilitated referral, respectively.

Smoking Up Among Some Populations During Pregnancy

August 15, 2017

Over the study period, smoking during pregnancy increased significantly among women with MDE (35.9 to 38.4%; P=0.02), while a decreasing trend among women without MDE only approached statistical significance (12.5 to 9.1%; P=0.07).

Opioid Epidemic Declared National Emergency

By August 11, 2017

Among the areas likely to benefit from increased funding are treatment centers, with the White House panel recommending rules be waived so that Medicaid recipients can get treatment for their addictions.

DEA Issues Comprehensive 'Drug Slang' List to Aid in Abuse Identification

August 11, 2017

In light of the plethora of street names used to refer to a number of drugs, the DEA has issued a comprehensive list for common drugs.

Marijuana Use May Increase Risk of Death from Hypertension

August 10, 2017

Over 19,569 person-years of follow-up, the adjusted hazard ratios for death from hypertension among marijuana users was 3.42 (95% confidence interval, 1.20 to 9.79).

Officials Concerned About Cocktails Served in Copper Mugs

By August 08, 2017

The advisory cites the Food and Drug Administration's Food Code which forbids copper to come in contact with foods that have a pH below 6.0. The Moscow Mule includes vodka, ginger beer and lime making it fall, as the bulletin says, "well below 6.0."

FDA: Herbal Remedy Linked to High Lead Levels, Developmental Delay in Child

By August 07, 2017

The risk of lead poisoning was initially communicated by the North Carolina Division of Public Health who tested the product and found high levels of lead.

Reasons for Buprenorphine Underuse ID'd in Physician Survey

August 04, 2017

The main reasons that physicians with waivers indicated no willingness to increase prescribing were lack of belief in agonist treatment (odds ratio, 3.98), lack of time for additional patients (odds ratio, 5.54), and belief that reimbursement rates are insufficient (odds ratio, 2.50).

Opioid Epidemic Needs to Be Declared a National Emergency, Says Special Commission

By August 01, 2017

The final recommendations - expected in the Fall - if implemented, will ensure that the Federal Government operates as a strong partner in the fight against addiction and the opioid crisis.

FDA Details Policy Plans for Regulating Tobacco Products

By July 28, 2017

The Agency believes decreasing nicotine levels could reduce the risk that future generations will become addicted to cigarettes in addition to allowing current addicts to quit.

ACOG Issues Guidance for Pregnancies Affected by Substance Abuse

July 28, 2017

The authors noted that there may be a select group of women who make an informed choice of medically supervised withdrawal, which should be under the care of an experienced physician and include long-term follow-up and support to help prevent relapse.

SAMHSA Evaluate Opioid Abuse Among Over 50s in the U.S.

July 27, 2017

Rates of opioid abuse among young adults - aged 18 to 25 - decreased from 11.5% in 2002 to 8.1% in 2014. But in adults 50 years and older, opioid abuse doubled, from 1.1 to 2.0%

ADHD Med Adherence and Long-Term Substance Abuse Risk Examined

July 25, 2017

Patrick Quinn, PhD, of Indiana University Bloomington, and colleagues looked at data from 2,993,887 Americans with ADHD.

Smoking Cessation Med Use Low in Older Patients After MI

July 21, 2017

Ninety-seven percent of smoking patients with MI received counseling, but few have SCM use

New Urine Test Quickly Detects Commonly Abused Rx Drugs

By July 19, 2017

The rapid detection tests consists of a self-contained collection cup and test device with auto-activated results seen in 5 minutes with no tipping of the cup.

Gender May Impact Efficacy of Smoking Cessation Pharmacotherapy

By July 19, 2017

The data showed TNP was significantly more effective vs. no medication assisted quit attempts for males (odds ratio [OR] 1.37, 95% CI: 1.02, 1.83; P=0.03) but not for females (OR 0.96, 95% CI: 0.71, 1.31; P=0.82).

DEA Proposes Rule to Deschedule Naldemedine

By July 18, 2017

Recently, Shionogi and Purdue received Food and Drug Administration (FDA) approval for naldemedine (Symproic) in the treatment of opioid-induced constipation in adults with chronic non-cancer pain.

What Effect Did FDA's APAP Limit Have on Liver Injury Incidence?

By July 17, 2017

Of the total 18,259 calls during the study period, 5.16% led to N-acetylcysteine administration in 2013 and 5.01% in 2015. Naloxone was administered in 3.63% and 4.02% of cases in 2013 and 2015, respectively.

Tramadol ER Looks Promising for Opioid Withdrawal Management

July 14, 2017

The data showed patients receiving buprenorphine (90.3%) were significantly more likely to be retained at the end of the taper vs. patients receiving clonidine (66.1%) but retention with tramadol ER (72.2%) was moderate and did not significantly differ from that of the other treatment arms (P=0.01).

CDC: One in Four Youth-Rated Movies Depict Tobacco Use

By July 07, 2017

Results showed that although incidents of tobacco use declined in youth-rated movies (from 31% in 2010 to 26% in 2016), in PG-13 movies alone, there was a significant jump of 43% from 2010 to 2016 (from 564 tobacco incidents to 809).

Drug Tampering by Healthcare Worker Causes Outbreak at Hospital

By July 07, 2017

The investigation found that that the nurse had replaced the active medication with saline or another solution. All of the patients recovered except one who died from a sepsis infection.

Impact of E-Cigarettes on Weight, Metabolic Parameters Examined

July 05, 2017

Even without nicotine exposure, similar delirious effects for e-cigarettes, traditional tobacco cigarettes

CDC: 'Health of the Nation' 40th Annual Report Published

June 30, 2017

Report includes trends of data for past 40 years, with increase in life expectancy, drop in infant mortality

Excessive Alcohol Consumption Linked to Biological Aging

June 27, 2017

"Our study showed that alcoholic patients have a shortened telomere length, which means that heavy drinking causes biological aging at a cellular level," said lead researchers, Naruhisa Yamaki, MD.

IV Lipid Emulsion for Bupropion Poisoning: Is it Beneficial?

By June 26, 2017

Researchers examined electronic records from one regional poison center for cases of intentional bupropion ingestion between January 1, 2009 to December 31, 2015. Reports that cited IV lipid emulsion administration or death as an outcome were further evaluated.

Medical Addiction Treatments Severely Lacking for Those Under 25

June 20, 2017

Over the study period, only 26.8% of young people treated for addiction to prescription opioids or heroin received either buprenorphine or naltrexone.

More Than Half of Overdose Deaths Linked to This Opioid

June 19, 2017

Researchers found that most of the 149 drug users they surveyed and interviewed feared and disliked fentanyl.

CDC: Number of Teens Vaping, Smoking Decreasing

June 16, 2017

Among white and Hispanic high school students, e-cigarettes were the most commonly used product.

NAS Proving to be 'Enormous' Burden for Hospitals

June 16, 2017

By 2012, neonatal abstinence syndrome was costing the United States nearly $316 million in hospital care — up from $61 million in 2003.