Poisoning & Drug Dependence

Researchers Hope to Test Heroin Vaccine in Humans Soon

By February 14, 2018

Researchers investigated 20 different carrier protein/adjuvant combinations.

Addressing Sensitive Topics With Patients: An Interview With Windel Stracener, MD

By February 14, 2018

"Patients must feel that you are empathetic and do not judge them. This is key not only to discussing weight, but to any subject that comes up," said Dr Windel Stracener, a family practitioner for 22 years.

Targeting Harm Perceptions Could Cut Teen E-Cigarette Use

February 12, 2018

Perceived harm from secondhand e-cigarette vapor showed similar patterns. Adolescents who use e-cigarettes are more likely to initiate using tobacco products than those who do not use e-cigarettes.

Spouse of Person With Alcohol Use Disorder at 'Rapid' Risk

February 08, 2018

After a first marriage to a spouse without AUD, the hazard ratios for AUD were 7.02 and 9.06, respectively, in women and men with a second marriage to a spouse with AUD.

FDA Analysis Shows Kratom Not "Just a Plant"

By February 07, 2018

Kratom should not be used to treat medical conditions, nor should it be used as an alternative to prescription opioids.

Motivation Has Little Overall Effect in Reducing Alcohol Consumption

February 05, 2018

Motivation did not have an effect on further reducing consumption, with the difference-in-differences effect actually suggesting average increase.

Do the Benefits of Smoking Cessation Tx Decrease Over Time?

By January 31, 2018

Benefits of smoking cessation medications decline over the first year.

Premature Unusual Amnesia Syndrome Linked to Substance Use

January 30, 2018

"To our knowledge this report is the first to associate fentanyl with this amnestic syndrome," the authors write.

How E-Cigarette Smoke May Damage DNA, Inhibit Repair

January 30, 2018

"These results indicate that nicotine nitrosation occurs in vivo in mice and that e-cigarette smoke is carcinogenic to the murine lung and bladder and harmful to the murine heart," the authors write.

Smokers Display Distorted Temporal Perception of Health Consequences

January 29, 2018

For both smokers and nonsmokers, the onset time estimates for mild conditions were associated with self-perceptions of risk and fear level of developing smoking-related conditions.

Study Examines Light Smoking Impact on Heart Disease, Stroke Risk

January 25, 2018

The researchers found that the pooled relative risk for coronary heart disease was 1.48 and 2.04, respectively, for smoking 1 and 20 cigarettes per day for men.

FDA: Increasing Number of Companies Selling Unapproved Opioid Cessation Txs

By January 24, 2018

These products have not been demonstrated to be safe or effective and may keep some patients from seeking appropriate, FDA-approved therapies.

DEA: Deregulation Allows NPs, PAs to Prescribe Opioid Use Disorder Treatment

By January 23, 2018

Nurse practitioners (NP) and physician assistants (PA) can now become DATA-Waived qualifying practitioners, allowing them to prescribe and dispense buprenorphine.

Impact of Marijuana Use on Cardiovascular Health Investigated

January 23, 2018

The researchers identified 13 studies examining associations between marijuana use and cardiovascular risk factors and 11 studies examining associations with clinical outcomes.

Smoking Prevalence in U.S. Didn't Significantly Change From 2015 to 2016

January 23, 2018

The researchers found that the prevalence of current cigarette smoking was 15.5% among adults in 2016, which marked a significant decline from 20.9% in 2005.

The "Tide Pod Challenge": A Bizarre Trend With Serious Health Consequences

By January 19, 2018

The trend, referred to as the 'Tide pod challenge' may seem unreal, but during the first 15 days of January the American Association of Poison Control Centers have already registered 39 cases of intentional consumption.

Walmart Offers Unique Opioid Disposal Solution With DisposeRx

By January 17, 2018

Packets contain a crosslinking polymer blend that, when added to the pill bottle with warm water, sequester any form of prescription drugs - including powders, pills, tablets, capsules, liquids or patches - into a non-divertible and biodegradable gel.

Is Pregabalin Effective for Benzodiazepine Discontinuation?

By January 11, 2018

For this study, researchers from the University of Michigan College of Pharmacy investigated the available evidence for the use of pregabalin in benzodiazepine discontinuation.

Noncigarette tobacco product use is associated with future cigarette smoking

January 04, 2018

Never-cigarette-smoking youths who initiated tobacco use with noncigarette products including e-cigarettes, hookahs, noncigarette combustible tobacco, or smokeless tobacco were more likely to smoke cigarettes in the following year than those who did not use noncigarette tobacco.

Are Pharmaceutical Aids for Smoking Cessation Effective?

January 02, 2018

No evidence that varenicline, bupropion, or nicotine replacement increase probability of abstinence

2009 to 2016 Shows Increase in Prenatal Marijuana Use

December 27, 2017

Greatest increases seen for pregnant females aged younger than 18 years, those aged 18 to 24 years

Higher Fruit Intake May Delay Lung Function Decline, Especially in Ex-Smokers

December 26, 2017

Apple, banana, tomato intake linked to slower decline in forced vital capacity in ex-smokers

CDC: 2016 Data Show Drop in Life Expectancy in U.S.

December 21, 2017

Increase in rate of age-adjusted drug overdose deaths observed during same time period

Smoking Cessation Drug Linked to Increased Risk of Cardiovascular Events

By December 20, 2017

The researchers analyzed the medical records of 56,851 new users of varenicline.

Urine Drug Monitoring Recommendations for Opioid Use in Chronic Pain

By December 15, 2017

For low-risk patient, testing should be conducted at least yearly, for those at moderate risk, ≥2 times a year, and for those at high risk, ≥3 times a year.

FDA Cracks Down on Companies Selling Street Drug Alternatives

By December 12, 2017

The warning letter explains how the claims made in the promotional materials for Legal Lean Syrup and Coco Loko demonstrate that the products are intended to be used as alternatives to illicit street drugs and that the products, as labeled and marketed, may pose safety concerns.

New Treatment Option for Opioid Use Disorder Gets Approval

By December 01, 2017

Sublocade should be used as part of a complete treatment program that includes counseling and psychosocial support.

Most Multi-Med Patients Have Not Discussed Possible Drug Interactions

November 30, 2017

In terms of who is responsible for talking to patients about possible drug interactions, 11, 26, and 63% felt that the pharmacist, doctor, and both doctor and pharmacist are responsible, respectively.

Performance-Enhancing Substances Sold Online May Contain Unapproved Ingredients

November 30, 2017

The researchers found that 23 of the 44 products marketed and sold as selective androgen receptor modulators contained 1 or more selective androgen receptor modulator.

Naloxone Effectiveness Compared by Route of Administration

November 28, 2017

Higher-concentration intranasal naloxone (2mg/mL) seems to have efficacy similar to that of intramuscular naloxone for reversal of opioid overdose, with no difference in adverse events.