Poisoning & Drug Dependence

Opioid Dependence Prevention Txs Compared in Head-to-Head Study

By October 18, 2017

Results found that all primary endpoints for non-inferiority of extended-release naltrexone group were met; retention in treatment (P=0.04), group proportion of total number of opioid-negative urine drug tests (P<0.001), days of heroin use (P<0.001) and days of other illicit opioids use (P<0.001).

Alcohol May Contribute to Premature Mortality in Psoriasis Patients

By October 17, 2017

The researchers compared an cohort of patients with psoriasis (≥18 years of age) drawn from several databases to 20 patients without psoriasis who were matched by age, sex, and general practice (n=55,537 and 854,314 respectively).

CVVH + Hemoperfusion Effective in Severe Metformin-Associated Toxicity

October 17, 2017

Case report describes treatment of female patient who attempted suicide with metformin overdose

Changing Marijuana Laws May Mean More Screening, Counseling Needed

October 10, 2017

In the changing legal environment, pediatric physicians must review their approach to screening for marijuana use and discussing the associated health consequences

Breath Sensor, App Combo Provide Novel Approach to Smoking Cessation

By October 06, 2017

The Carbon Monoxide Breath Sensor System (COBSS) informs the user how breath carbon monoxide levels are affected by their smoking behavior.

Electrolyte Disturbances Common Among Patients with Alcohol-Use Disorder

October 06, 2017

Telltale signs of chronic alcohol use are large drops in plasma phosphate, magnesium, potassium, calcium

E-Cigarette Switch Strategy Linked to Fewer Premature Deaths

October 04, 2017

Under pessimistic model, 1.6 million premature deaths prevented, 20.8 million fewer life-years lost

CVS Plans to Limit Opioid Rxs to 7-Day Supply for Certain Patients

By September 22, 2017

At the pharmacy level, a greater emphasis will be placed on counseling to help patients understand the risks associated with opioid use based on the new Centers for Disease Control and Prevention (CDC) guidelines.

'Death Wish' Coffee Recalled Due to Deadly Toxin Risk

By September 21, 2017

The company reached the decision with an outside Process Authority, who determined that their manufacturing process had the potential to create the deadly toxin botulin.

FDA: MAT Should Not Be Withheld from Patients on CNS Depressants

By September 20, 2017

"the dangers associated with failing to treat an opioid use disorder can outweigh the risks of co-prescribing MAT and benzodiazepines," said FDA Commissioner Scott Gottlieb.

Opioid, Unintentional Injury Deaths Contribute to Life Expectancy Decline

September 20, 2017

The researchers observed an increase in life expectancy at birth from 2000 to 2015, from 76.8 to 78.8 years.

Teens Given Opioid Rx After Surgery More Likely to Be Persistent Users

By September 15, 2017

Results showed that new persistent opioid use, defined as continued opioid prescription fills between 90 and 180 days after the index surgical procedure, were 4.8% compared to 0.1% in the non-procedure control group.

AAP: ER Visits for Kids Testing Positive for Opioids on the Rise

September 15, 2017

ER visits for opioid dependence/abuse increased from 32,235 in 2008 to 49,626 in 2013

First Prescription-Only App Approved for SUD Patients

September 15, 2017

The newly-approved app delivers behavioral therapy that's designed to "increase abstinence from substance abuse and increase retention in outpatient therapy programs," the FDA said.

Daily Consumption of 'Cancer Preventative' Leads to Cyanide Poisoning

By September 13, 2017

The patient admitted to taking 2 teaspoons of self-prepared apricot kernel extract along with 3 tablets of Novodalin, an herbal fruit kernel supplement, every day for the past 5 years.

Airplane Medical Emergencies: Is it a Physician's Duty to Help?

September 13, 2017

In the United States, Canada, and United Kingdom, physicians do not have the legal duty to assist unless there is a prior patient-physician relationship.

Increase in Atrial Stiffness During First 30-Minutes of Post E-Cig Inhalation

September 12, 2017

The researchers found that during the first 30 minutes following e-cigarette inhalation with nicotine, there was a significant increase in blood pressure, heart rate and arterial stiffness.

FDA: Separate Dosing of Potassium-Lowering Drug from Other Oral Meds

By September 06, 2017

The Food and Drug Administration (FDA) is recommending that patients avoid the concomitant use of sodium polystyrene sulfonate with other oral medications.

CDC: Illicitly Manufactured Fentanyl Key Player in U.S. Overdose Deaths

September 01, 2017

The synthetic drug is more powerful than heroin or morphine

Dose or Duration of Rx: Which Has Greater Impact on Opioid Use Disorder?

August 24, 2017

Patients were more likely to continue using the opioids if they were initially prescribed medications for a longer time.

Why the FDA's Novel Plan for Nicotine Is a Step in the Right Direction

August 23, 2017

To put the scourge of conventional cigarettes in context, smoking kills 15 times more Americans per year than opioids.

Opioid Prescribing, Use Continues Even After Overdose

August 23, 2017

Of the 3,945 who had overdosed on prescription opioids, prescriptions decreased from 32.4% before the overdose to 28.3% after. Meanwhile, the number of patients receiving medication-assisted treatment rose from 29.4 to 33.0% after a heroin overdose.

Few Hospitalized CHD Patients Receive Smoking Cessation Therapy

August 22, 2017

Overall, 22.7 percent received smoking cessation pharmacotherapy, most often the nicotine patch

Smoking Cessation Therapies

August 18, 2017

Smoking cessation therapy regimens of prescription drugs and over-the-counter medications used to help patients quit smoking.

One-Step Drug Test Cup Gains FDA Clearance for OTC Use

By August 16, 2017

The FDA's marketing clearance applies to 13 commonly abused drugs; there are multiple cut-off options available for certain drugs.

Is ED-Initiated Buprenorphine for Opioid Dependence Cost Effective?

By August 16, 2017

Results showed that the mean costs over the next 30 days after ED visits were $1,752, $1,805 and $1,977 for ED-initiated buprenorphine, referral alone and brief intervention with facilitated referral, respectively.

Smoking Up Among Some Populations During Pregnancy

August 15, 2017

Over the study period, smoking during pregnancy increased significantly among women with MDE (35.9 to 38.4%; P=0.02), while a decreasing trend among women without MDE only approached statistical significance (12.5 to 9.1%; P=0.07).

Opioid Epidemic Declared National Emergency

By August 11, 2017

Among the areas likely to benefit from increased funding are treatment centers, with the White House panel recommending rules be waived so that Medicaid recipients can get treatment for their addictions.

DEA Issues Comprehensive 'Drug Slang' List to Aid in Abuse Identification

August 11, 2017

In light of the plethora of street names used to refer to a number of drugs, the DEA has issued a comprehensive list for common drugs.

Marijuana Use May Increase Risk of Death from Hypertension

August 10, 2017

Over 19,569 person-years of follow-up, the adjusted hazard ratios for death from hypertension among marijuana users was 3.42 (95% confidence interval, 1.20 to 9.79).