Generic Name and Formulations:
Hydroxychloroquine sulfate 200mg; tabs.
Company:
Covis Pharmaceuticals, Inc.
Refractory rheumatoid arthritis or lupus erythematosus.
Rheumatoid arthritis: initially 400–600mg daily with food or milk. Lupus: initially 400mg 1–2 times daily. Maintenance for both: 200–400mg daily.
Not recommended.
DMARD (aminoquinoline).
Long-term use in children. Retinal or visual field changes.
Be fully familiar with this product's toxicity before use. Psoriasis. Porphyria. Hepatic dysfunction. Alcoholism. G6PD deficiency. Monitor ocular function, reflexes, and blood in chronic use. Discontinue if blood dyscrasias, visual symptoms or muscular weakness occur or if ineffective after 6 months in rheumatoid arthritis. Pregnancy: not recommended. Nursing mothers.
Avoid other hepatotoxic or dermatotoxic drugs.
Irreversible retinopathy, blurred vision, corneal edema or deposits, visual field defects, irritability, neuromuscular dysfunction, hair bleaching, alopecia, pruritus, skin pigmentation, rash, blood dyscrasias, anorexia, nausea, weight loss.
Tabs—100
Suppression and treatment of susceptible malaria.
Suppression (start 2 wks before and continue for 8 wks after trip): 400mg every 7 days. Treatment: initially 800mg; then 400mg 6, 24, and 48 hrs after 1st dose.
Suppression (start 2 wks before and continue for 8 wks after trip): 6.45mg/kg (max 400mg) every 7 days. Treatment: initially 12.9mg/kg (max 800mg); then 6.45mg/kg (max 400mg) 6, 24 and 48 hrs after 1st dose.
Aminoquinoline.
Long-term use in children. Retinal or visual field changes.
Before using this product, be fully familiar with its toxicity. Hepatic dysfunction. Alcoholism. Psoriasis. Porphyria. G6PD deficiency. Monitor ocular function, reflexes, and blood in long-term use. Discontinue if blood dyscrasias occur. Children. Pregnancy. Nursing mothers.
Avoid other hepatotoxic or dermatotoxic drugs.
Headache, dizziness, GI upset.
Tabs—100