Initially 5mg twice daily. May increase after 3–4 wks in 10mg increments; max 60mg daily.
Asthma. Severe bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.
Severe COPD. Ischemic heart disease or failure. Renal or hepatic dysfunction. Diabetes. Hyperthyroidism. Surgery. Avoid abrupt cessation. Pregnancy (Cat.B). Nursing mothers: not recommended.
Hypotension with prazosin, reserpine. Adjust antidiabetic medications. Caution with verapamil, catecholamine-depleting drugs. May block epinephrine, β-agonists. Potentiated by thioridazine.
Muscle pain, insomnia, dizziness, fatigue, anxiety, joint pain, edema, dyspnea, GI upset, paresthesias, chest pain, pruritus, bradycardia, bronchospasm, heart failure or block, angina.
Formerly known under the brand name Visken.