FDA Approves the Use of Luzu Cream in Younger Patients

By February 23, 2018

Luzu, an azole antifungal, is indicated for the topical treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum and Epidermophyton floccosum.

Anthropometric failure in children related to intra-population variation in health determinants

February 23, 2018

Differences in health determinants within populations have a greater effect on anthropometric status of children than differences in population level health determinants in low- and middle-income countries (LMICs).

Cognitive Impact of Chronic Kidney Disease in Children, Investigated

February 23, 2018

The mean differences in FSIQ were −10.5 for all CKD stages, −9.39 predialysis, −16.2 for dialysis, and −11.2 for transplant compared with the general population.

Pharmacologic Tx for Severe Neonatal Jaundice to Be Reviewed by FDA

By February 23, 2018

The FDA has set an action date of August 22, 2018 to respond to the NDA

ACIP Votes in Favor of Intranasal Flu Vaccine Flumist Quadrivalent

By February 22, 2018

The Advisory Committee on Immunization Practices (ACIP) has voted in favor of a renewed recommendation for the use of Flumist Quadrivalent (Influenza Vaccine Live, Intranasal).

Infant Gut Microbiota May Mediate Intergenerational Transmission of Obesity

February 22, 2018

The researchers found that infants born vaginally to overweight or obese mothers were significantly more likely to become overweight at age 1 year, compared with being born vaginally to a normal-weight mother (adjusted odds ratio, 3.33).

New Test May Help Diagnose Autism Earlier in Children

By February 20, 2018

In this study, researchers explored the association of proteotoxic damage with autism spectrum disorder.

CDC: Elevated Flu Activity Expected to Continue for Several More Weeks

By February 16, 2018

So far this season, influenza A(H3N2) viruses have predominated, but other influenza viruses are also circulating.

Treatment With Homemade Enema Leads to Colitis in Two Children

By February 14, 2018

A national survey showed that only about 7% of consumers read warning labeling on over-the-counter products.

Cystic Fibrosis Combo Treatment Symdeko Gets FDA Approval

By February 13, 2018

Symdeko is Vertex's third medicine approved to treat the underlying cause of CF.

Breath-Actuated Qvar RediHaler Available for Asthma Maintenance Treatment

By February 12, 2018

Qvar RediHaler (beclomethasone dipropionate HFA) Inhalation Aerosol is a breath-actuated inhaled prescription medicine used as a maintenance treatment for the prevention and control of asthma in people 4 years of age and older.

Differences in sudden unexpected infant death rates reported between states

February 12, 2018

National sudden unexpected infant death (SUID) rates had the steepest decline during the 1990 to 1998 study time period, followed by slower decline during 1999 to 2015.

Wide Variance of Sudden Infant Death Rates by State

February 12, 2018

The researchers found that from 1990 to 2015 there was a decrease in SUID rates from 154.6 to 92.4 per 100,000 live births, with a 44.6% decrease from 1990 to 1998 and a 7% decrease from 1999 to 2015.

Targeting Harm Perceptions Could Cut Teen E-Cigarette Use

February 12, 2018

Perceived harm from secondhand e-cigarette vapor showed similar patterns. Adolescents who use e-cigarettes are more likely to initiate using tobacco products than those who do not use e-cigarettes.

CDC Reports Level of Significant Head Injuries Among U.S. Children

February 09, 2018

The percentage of children who have ever had a significant head injury also increased as age increased, peaking at 11.7% among 15-to-17-year-old children.

Survey: Most At-Risk Patients Don't Carry Two Epinephrine Auto-Injectors

By February 08, 2018

Most respondents did not carry 2 EAIs in order to keep 1 EAI in another location.

Has Family Integrated Care in the NICU Affected Outcomes?

February 08, 2018

For infants in the FICare group, the high-frequency exclusive breastmilk feeding rate at discharge was higher than that seen in those in the standard care group (70 versus 63%; P=0.016).

Year-Long School Fitness Program Shows No Difference in Child BMI

February 08, 2018

No significant reduction in BMI z score at 15 or 30 months of healthy lifestyle program intervention.

Prevalence of Fetal Alcohol Spectrum Disorder Examined in the U.S.

February 07, 2018

For fetal alcohol spectrum disorders, the conservative prevalence estimates varied from 11.3 to 50.0 per 1,000 children; the weighted prevalence estimates varied from 31.1 to 98.5 per 1,000 children.

ACIP: 2018 Immunization Schedule for Children, Adolescents Available

By February 06, 2018

The recommended childhood and adolescent immunization schedules for 2018 have been approved by the American Academy of Pediatrics, the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (CDC), the American Academy of Family Physicians, and the American College of Obstetricians and Gynecologists.

Low-Carb Diets Linked to Increased Risk of Neural Tube Defects

February 06, 2018

First study to assess the effect of carb intake on neural tube defects, postfortification with folic acid

Antibiotic Prophylaxis Rates Low for Pediatric Sickle Cell Patients

February 06, 2018

Data were included for 2,821 children with 5,014 person-years. The researchers found that 18 percent of children received ≥300 days of antibiotics.

To What Extent Can Postnatal Depression Impact Child Behavior?

February 02, 2018

For mothers with moderate, marked, and severe PND, the odds ratios for child behavioral disturbance were 2.22, 1.91, and 2.39, respectively.

Zomacton Approved to Treat Growth Hormone Deficiency in Adults

By February 01, 2018

Zomacton now approved for replacement of endogenous GH in adults with GH deficiency.

Are Psychiatric Drugs Being Overprescribed in Children and Adolescents?

By January 30, 2018

"Our results show that, at a population level, prescriptions of stimulants and antidepressant medications for children and adolescents do not appear to be prescribed at rates higher than the known rates for psychiatric conditions they are designed to treat," said the study's lead author, Dr. Ryan Sultan.

FDA Expands Pediatric Age Range for MultiHance Contrast Agent

By January 30, 2018

The FDA's approval was supported by data specifically gathered in patients aged <2 years. The 0.1mmol/kg dose significantly improved the visualization and morphologic assessment of CNS lesions as seen in older pediatric patients and adults.

Greater rates of mortality linked to infants at risk for maltreatment

January 29, 2018

Infants classified as very high risk for substantiated maltreatment had a higher relative risk of overall mortality, death through unintentional and inflicted injury, and sudden unexpected infant death.

Specific White Matter Patterns Linked to Youth Psychopathology

January 29, 2018

The feature most associated with both of these traits was a brain white matter pattern reflecting frontotemporal connectivity and crossing fibers in the uncinate fasciculus.

CDC: Increase in Birth Defects May be Zika-Related

January 29, 2018

The researchers identified a non-statistically significant increase in total birth defects potentially related to Zika virus infection in areas with local transmission, from 2.8 to 3.0 cases per 1,000 live births in the first and second halves of 2016, respectively (P=0.10).

AHRQ: Update on ADHD Diagnosis and Treatment

By January 26, 2018

Evidence was contributed from 103 articles describing 90 unique studies.