Pediatrics

Peanut Allergy Tx Efficacy Examined in 4-Year Follow-Up Study

By August 17, 2017

Results found that 4 children initially treated with PPOIT and 6 treated with placebo had allergic reactions to peanut intake, none experience prophylaxis.

Sleep Duration and Diabetes Risk in Children: What's the Link?

August 15, 2017

A one-hour longer sleep duration correlated with 0.19 kg/m² lower body mass index, 0.03 kg/m5 lower fat mass index, 2.9% lower homeostasis model assessment of insulin resistance, and 0.24% lower fasting glucose.

Regeneron to Discontinue Development of RSV Treatment

By August 14, 2017

The primary endpoint of RSV prevention - assessed through day 150 of treatment - was not significantly reached.

Data Support ACIP Decision Not to Use Live Attenuated Flu Vaccine

August 10, 2017

The researchers found that 19% of the 6,879 eligible participants tested positive for influenza virus, predominantly for A(H1N1)pdm09 and influenza B (11 and 7%, respectively).

Mutation Subtypes ID'd in Infant Diabetes

August 09, 2017

The researchers found that the most common form of infancy-onset diabetes was KCNJ11-related diabetes (37.5%), followed by "unknown" (likely type 1 diabetes; 21.6%).

FDA: Herbal Remedy Linked to High Lead Levels, Developmental Delay in Child

By August 07, 2017

The risk of lead poisoning was initially communicated by the North Carolina Division of Public Health who tested the product and found high levels of lead.

New Treatment Option for Hereditary Tyrosinemia Type 1 Approved

By August 01, 2017

The safety and efficacy of Nityr have been established based on studies of another oral formulation of nitisinone in patients with HT-1.

Xatmep Now Available for Pediatric ALL, pJIA

By July 31, 2017

Methotrexate works by inhibiting dihydrofolic acid reductase, which interferes with DNA synthesis, repair, and cellular replication.

FDA Details Policy Plans for Regulating Tobacco Products

By July 28, 2017

The Agency believes decreasing nicotine levels could reduce the risk that future generations will become addicted to cigarettes in addition to allowing current addicts to quit.

Varibar Nectar Approved for Oropharyngeal Function Testing

By July 28, 2017

Varibar Nectar — with target viscosity 300 CPS — comes in an apple flavor for improved patient compliance and is designed to provide the least coating properties necessary to visualize the swallowing process.

Acute Otitis Media Treatments

July 28, 2017

Acute otitis media treatment chart including select antibiotics and recommended doses.

Haegarda Available for Routine Prophylaxis of Hereditary Angioedema Attacks

By July 25, 2017

Haegarda reduced the number of HAE attacks by a median of 95% vs. placebo

Oral Allergy Treatments: OTC

July 25, 2017

A comparative dosing chart of over-the-counter (OTC) medications for allergy treatment.

Vaccine Hesitancy Linked to Substantial Public Health Consequences

July 25, 2017

The researchers determined that just a 5% drop in measles, mumps, and rubella vaccine coverage would triple the number of measles cases in children aged 2 to 11 years nationally every year.

Long-Term Data for Isentress HD Reinforce Safety, Efficacy

By July 24, 2017

Data from Week 48 previously showed that once-daily Isentress HD achieved the primary efficacy endpoint of non-inferiority vs. twice-daily Isentress.

FDA Expands Yervoy Use for Pediatric Melanoma

By July 24, 2017

A population pharmacokinetic analysis (n=565) showed that Yervoy exposure in patients aged ≥12 years was similar to that in adults at the approved 3mg/kg dose given intravenously (IV) over 90 minutes every 3 weeks for a total of doses.

FDA Clears First MRI Device for Neonatal Imaging in NICU

By July 21, 2017

The Embrace Neonatal MRI System is specifically designed for imaging of the neonatal head (head circumference up to 38cm and weight of 1 - 4.5kg).

Seqirus Begins Shipping Flu Vaccines for 2017/18 Season

By July 21, 2017

Specific vaccines in the Seqirus portfolio for the upcoming flu season include Afluria Quadrivalent (ages ≥18 years), the egg-based quadrivalent influenza vaccine, and Afluria (ages ≥5 years) and Fluvirin (ages ≥4 years), the egg-based trivalent influenza vaccines.

Does Winter Vitamin D Supplementation Reduce URI Risk in Children?

July 21, 2017

High dose supplementation did not reduce overall wintertime upper respiratory tract infections

FDA Expands Use of RELiZORB to Include Children

By July 20, 2017

In the study, authors measured plasma omega-3 fatty acid concentrations as markers of fat absorption. Safety and tolerability were assessed by documentation of gastrointestinal (GI) symptoms.

PANS/PANDAS Treatment Guidelines Released

By July 20, 2017

"Immunomodulatory therapy should be considered early, because NSAIDs or a short course of oral corticosteroids may be sufficient for symptom remission in recent-onset cases, whereas those with long-standing symptoms often require more intensive and prolonged immunotherapeutic interventions," the authors write.

Widespread Shipment of Fluzone Product Line Will Begin in Early August

By July 18, 2017

The Fluzone vaccines should not be given to any individual with a severe allergic reaction to any vaccine component, including eggs, egg products, thimerosol, or to a previous dose of any flu vaccine.

Many Parents Unsure About Teen Vaccine Schedules

By July 17, 2017

Surveyed parents reported that an appointment scheduled by the provider (44%), mentioning vaccination during an office visit by a clinician (40%), or a reminder sent by the clinician's office (11%) were the primary methods by which they were informed of the need for additional vaccines.

Maternal Antidepressant Use and Offspring Disability: What's the Link?

July 13, 2017

No significant association for use of antidepressant in pregnancy, child's intellectual disability

Aquaphor Baby Fast Relief Paste Available for Diaper Rash

By July 12, 2017

Aquaphor Baby Fast Relief Paste is available in 3.5oz (99g) tubes.

Pesticide-Free Lice Treatment Gets FDA Clearance

By July 11, 2017

Resultz is an odorless treatment that kills and removes head lice with a 5 minute application time; this is the shortest time frame associated with currently available lice products.

WHO: Resistance to Last-Resort Gonorrhea Tx Seen in 66% of Countries

By July 10, 2017

Gonorrhea is a sexually transmitted infection (STI) that can affect the genitals, rectum, and throat. Complications include pelvic inflammatory disease, ectopic pregnancy, infertility, and an increased risk of HIV.

FDA Approves New Sickle Cell Disease Treatment

By July 07, 2017

The safety and efficacy of Endari were evaluated in a randomized clinical trial involving patients aged 5-58 years with sickle cell disease who had ≥2 painful crises within 12 months prior to trial enrollment.

Topical Steroid Potencies

July 07, 2017

Topical steroid classification chart sorted by potency.

Probiotics Show Little Efficacy in Protecting Infants

July 06, 2017

The average number of days missed was 11 for both groups. And based on parents' daily reports, there were no differences in cold symptoms, diarrhea, fever, or vomiting.