Pediatrics

CDC Updates Zika Guidance With 3 Clinical Scenarios

October 20, 2017

"Health care providers should remain alert for abnormal findings in infants with possible congenital Zika virus exposure without apparent abnormalities at birth," the authors write.

IDSA: New Clinical Practice Guidelines on Infectious Diarrhea Management

By October 19, 2017

The expert panel states that for the majority of patients with diarrhea, diagnostic testing is unnecessary.

Higher RSV Hospitalization Risk in Preemies After 2014 Guidance

By October 18, 2017

A decline in immunoprophylaxis was associated with an increased risk of RSV hospitalization among infants 29-34 weeks gestational age who were <6 months of age for both commercial- and Medicaid-insured.

Safety of Systemic Medications Investigated in Pediatric Psoriasis

By October 17, 2017

Methotrexate was the most commonly used agent (270 patients [69.2%]), followed by biologic agents, primarily etanercept (106 [27.2%]), acitretin (57 [14.6%]), cyclosporine (30 [7.7%]), and fumaric acid esters by (19 [4.9%]). Seventy-three patients (18.7%) used ≥1 medication.

Stelara Approved to Treat Adolescent Patients With Plaque Psoriasis

By October 16, 2017

The expanded approval was supported by data from a Phase 3 study that evaluated the safety and efficacy of subcutaneous Stelara in adolescents aged ≥12 years.

AAP Releases New List of 'Choosing Wisely' Recommendations

October 11, 2017

The AAP Section for Endocrinology compiled a list of tests that parents and physicians should question.

USPSTF Issues Draft Recommendation on Counseling to Prevent Skin Cancer

October 11, 2017

The researchers recommend that clinicians provide counseling on sun protection behaviors for anyone with fair skin aged 6 months to 24 years, including parents of young children with fair skin (B recommendation).

Insulin Pump Therapy Linked to Better Outcomes in Young T1D Patients

October 11, 2017

Compared with injection therapy, pump therapy was correlated with lower rates of severe hypoglycemia (9.55 versus 13.97 per 100 patient-years) and diabetic ketoacidosis (3.64 versus 4.26 per 100 patient-years).

Changing Marijuana Laws May Mean More Screening, Counseling Needed

October 10, 2017

In the changing legal environment, pediatric physicians must review their approach to screening for marijuana use and discussing the associated health consequences

Novel Vagus Nerve Stimulation Device Approved for Drug-Resistant Epilepsy

By October 10, 2017

The system includes a detect-and-respond mode, which is designed to prevent seizures before they start and deliver therapy to stop them if they do.

Live Flu Vaccine Withdrawal Not Linked to Change in Immunization Rates

October 06, 2017

Withdrawal of live attenuated influenza vaccine recommendation not linked to change in rates

Maternal Multivitamin Use and Autism Spectrum Disorder: What's the Link?

October 05, 2017

Lower odds of offspring autism spectrum disorder with or without additional iron or folic acid

Updated HCV Guidance Focuses on Additional Patient Populations

By October 03, 2017

The updates include a primer on HCV resistance and guidance on treating patients who have undergone kidney transplantation.

Triptodur Now Available to Treat Central Precocious Puberty

By October 03, 2017

Triptodur, a gonadotropin-releasing hormone (GnRH) agonist, is given as an intramuscular (IM) injection every 6 months.

2017 Vaccination Schedule: 0-18 Years of Age

October 03, 2017

This schedule indicates the recommended ages for routine administration of currently licensed childhood vaccines for children 0-18 years of age.

Antibiotic Combo Tx May Up Risk of Acute Kidney Injury in Children

October 03, 2017

Risk of AKI in hospitalized children higher than with IV vancomycin, other antipseudomonal -lactam

Tdap Vaccination During Pregnancy Protects Infants From Pertussis

October 02, 2017

Multivariable vaccine effectiveness estimate 77.7 percent for Tdap administered during third trimester

Genvoya Approved for Use in Children with HIV Weighing at Least 25kg

By September 27, 2017

Based on this new data, Genvoya is now indicated to treat adult and pediatric patients weighing ≥25kg compared to the previous ≥35kg requirement.

Antidepressant Overdose Risk Should Be Considered When Choosing Depression Tx

By September 26, 2017

Results showed that bupropion users were more likely to have a seizure, have accompanied tachycardia on presentation, and be admitted to the hospital, compared to those who ingested a TCA.

Tuberculosis Vaccine May Carry Dermatological Benefits for Newborns

September 25, 2017

There was a significant difference in the effect of neonatal BCG vaccination between children with atopic predisposition and children without atopic predisposition.

AAP Explores Major Infectious Disease Risk Factors in Team Sports

September 25, 2017

The researchers found that skin-to-skin contact with athletes who have active skin infections, environmental exposures, and physical trauma are major risk factors for infection, as well as sharing of equipment and contact with contaminated fomites.

Post-Food Consumption Cardiac Arrest May Indicate Rare Heart Condition

By September 22, 2017

Researchers concluded that vagal stimulus-dependent SCA after eating a large bite of food may be the first symptom of BS.

Rapivab Approved for Use in Children with Acute Uncomplicated Influenza

By September 21, 2017

Rapivab inhibits influenza virus neuraminidase, an enzyme that releases viral particles from the plasma membrane of infected cells. The antiviral activity of peramivir was determined in cell culture.

Survey Reveals Change in Pediatrician Attitudes to Breastfeeding

September 20, 2017

However, their confidence in breastfeeding success, managing problems declining

Humalog Junior KwikPen Soon to Be Available

By September 19, 2017

Humalog Junior KwikPen U-100 will be available as 5-count cartons. The BD pen needles are recommended for use with Humalog Junior KwiKPen.

AAP Publish First Guidance on Tattooing, Piercing for Adolescents

By September 18, 2017

These can occur from contamination of the inks or diluents used for tattooing.

Adzenys ER Approved for the Treatment of ADHD

By September 18, 2017

Adzenys ER is a once-daily extended-release liquid that does not need to be reconstituted or refrigerated.

Does Prenatal Biologic Therapy for IBD Affect Infant Vaccine Response?

By September 18, 2017

In addition, the researchers assayed umbilical cord blood samples from 33 infants to assess the concentration of biologic agents.

Teens Given Opioid Rx After Surgery More Likely to Be Persistent Users

By September 15, 2017

Results showed that new persistent opioid use, defined as continued opioid prescription fills between 90 and 180 days after the index surgical procedure, were 4.8% compared to 0.1% in the non-procedure control group.

AAP: ER Visits for Kids Testing Positive for Opioids on the Rise

September 15, 2017

ER visits for opioid dependence/abuse increased from 32,235 in 2008 to 49,626 in 2013