Pancreatic/Thyroid/Other Endocrine Cancers

Underlying Mechanisms ID'd in Curcumin Resensitization of CA Cells

August 02, 2017

The researchers reported the resensitization of chemoresistant PDAC cells by curcumin through inhibition of the PRC2-PVT1-c-Myc axis.

First-in-Class Pancreatic Cancer Drug Gains Orphan Drug Status

By June 21, 2017

Clinical trials of pamrevlumab are currently ongoing for conditions such as idiopathic pulmonary fibrosis, pancreatic cancer, and Duchenne muscular dystrophy.

USPSTF Issues Recommendation on Thyroid Cancer Screening

May 10, 2017

U.S. Preventive Services Task Force reaffirms guidelines it issued in 1996 and 2016

ASCO: Pancreatic Cancer Treatment Update

April 17, 2017

Regimen of gemcitabine, capecitabine preferred in absence of concerns for toxicity, tolerance

Massage Improves Pain, Lymphedema in Female CA Patients

March 10, 2017

The researchers found that all participants reported a positive experience with aromatherapy massage.

Xermelo Approved for Carcinoid Syndrome Diarrhea

By March 01, 2017

That FDA has approved Xermelo (telotristat ethyl) tablets as the first oral treatment for carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy in adults inadequately controlled by SSA therapy.

Regular Aspirin Use May Reduce Pancreatic Cancer Risk

December 21, 2016

Regular aspirin use is associated with reduced risk of pancreatic cancer in a Chinese cohort, according to a study published online in Cancer Epidemiology, Biomarkers & Prevention.

USPSTF Issues Statement on Thyroid Cancer Screening

November 23, 2016

Widespread routine thyroid cancer screening can lead to overdiagnosis, overtreatment

Do NSAIDs, Statins Reduce Pancreatic Cancer Risk?

By November 09, 2016

Findings from previous studies have been conflicting.

Linear Relation Between Age and Survival in Papillary Thyroid Cancer

November 02, 2016

For patients with papillary thyroid cancer (PTC), patient age is associated with death in a linear fashion, with no apparent age cut point demarcating survival difference, according to a study published online in the Journal of Clinical Oncology.

Metformin Tied to Increased Survival in Pancreatic CA Patients

By July 27, 2016

For pancreatic ductal adenocarcinoma (PDAC) patients with diabetes, metformin treatment was associated with an increase in survival. Those were the findings of a new study published in the American Journal of Gastroenterology.

Vitamin D Levels Tied to Survival in Pancreatic Cancer

June 22, 2016

Longer overall survival for patients with sufficient prediagnostic 25-hydroxyvitamin D

FDA Designates Selumetinib Orphan Drug for Differentiated Thyroid CA

By May 17, 2016

AstraZeneca announced that the FDA has granted Orphan Drug designation to selumetinib for the adjuvant treatment of patients with stage III or IV differentiated thyroid cancer (DTC).

OTC Anti-Radiation Drug Gets FDA Approval

By May 17, 2016

Mission Pharmacal announced that the Food and Drug Administration (FDA) has approved its Abbreviated New Drug Application (ANDA) for over-the-counter liquid Potassium Iodide Oral Solution for use in the event of a nuclear emergency.

Study Tests Additional Tx for Improving Survival in Advanced Pancreatic Cancer

May 04, 2016

Neither extra chemotherapy drug nor add-on radiation aided longevity in French trial

Cancer Deaths Declining by 1.5% a Year in the U.S.

March 10, 2016

Overall rates of cancer and cancer mortality in the United States continue to decline, according to the Annual Report to the Nation on the Status of Cancer.

Afinitor Receives Additional FDA Approval

By February 26, 2016

Novartis' Afinitor (everolimus) has been approved by the Food and Drug Administration (FDA) for the treatment of patients with progressive, well-differentiated non-functional, neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin with unresectable, locally advanced or metastatic disease.

Concerns Over Incretin-Based Drugs, Pancreatic Cancer Risk Addressed in New Study

By February 22, 2016

A new international, multicenter study has found that incretin-based drugs, used to treat type 2 diabetes, are not associated with an increased risk of pancreatic cancer.

Thyroid CA Patients Report Poor QOL, Despite Good Prognoses

December 29, 2015

Quality of life lower than that seen among survivors of colorectal, breast, and other types of cancer

Burden, Costs of Gastrointestinal, Liver Disease Estimated in U.S.

December 02, 2015

GI hemorrhage is most common diagnosis leading to hospitalization, with cost of 5 billion in 2012

New Pancreatic Cancer Treatment Available

By October 29, 2015

The FDA has approved Onivyde (irinotecan liposome injection; Merrimack) as part of a combination regimen with fluorouracil (5-FU) and leucovorin for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy.

Onivyde for Advanced Pancreatic Cancer Granted FDA Approval

By October 22, 2015

The Food and Drug Administration (FDA) has approved Onivyde (irinotecan liposome) injection in combination with fluorouracil and leucovorin for the treatment of metastatic pancreatic cancer who have been previously treated with gemcitabine-based chemotherapy.

Obesity Associated With Thyroid Cancer Risk

September 24, 2015

Obesity is associated with increased risk of thyroid cancer, according to a review published in Obesity Reviews.

'Epidemic of Diagnosis' in Thyroid Cancer

September 17, 2015

Many cases involve low-risk tumors where treatments could carry greater risks than benefits

Irreversible Electroporation Promising in Pancreatic CA

September 04, 2015

Irreversible electroporation (IRE) in pancreatic cancer cells may improve survival rates for some patients, new research suggests.

In Thyroid CA Radioiodine Ablation, rhTSH Better for HRQoL

August 07, 2015

For patients with thyroid cancer, recombinant human thyroid-stimulating hormone (rhTSH) prevents the transient deterioration of health-related quality-of-life (HRQoL) seen with use of thyroid hormone withdrawal (THW) at 131I administration.

Urine Test May Help ID Pancreatic Cancer Earlier

August 04, 2015

Elevated levels of three proteins detected in urine of early-stage pancreatic cancer patients

Six Lots of Cancer Drug Adrucil Recalled

By July 24, 2015

Teva announced a voluntary recall of 6 lots of Adrucil (fluorouracil injection) 5g/100mL (50mg/mL) due to potential particulate matter identified as aggregate of silicone rubber pieces from a filler diaphragm and fluorouracil crystals.

Does Pioglitazone Increase Bladder Cancer Risk?

July 21, 2015

A statistically significant increased risk of bladder cancer was not found with the use of pioglitazone, although a small increased risk could not be excluded, according to an analysis published in JAMA.

Protein May Help Identify Pancreatic Cancer Early

June 26, 2015

A cell surface proteoglycan, glypican-1 (GPC1), on circulating exosomes may serve as a potential noninvasive diagnostic and screening tool to detect early stages of pancreatic cancer.