Oral Calcium Channel Blockers for Hypertension
| ORAL CALCIUM CHANNEL BLOCKERS FOR HYPERTENSION | |||||
|---|---|---|---|---|---|
| Generic | Brand (Company) |
Strength(s) available | Formulation | Pharmaceutical design | Regimen |
| BENZOTHIAZEPINES | |||||
| DILTIAZEM | Cardizem LA
(AbbVie) |
120mg, 180mg, 240mg, 300mg, 360mg, 420mg | ext-rel tabs | graded release tabs | once daily |
| Cardizem CD
(AbbVie) |
120mg, 180mg, 240mg, 300mg, 360mg | ext-rel caps | coated beads in caps | once daily | |
| Dilacor XR
(Actavis) |
120mg, 180mg, 240mg | ext-rel caps | ext-rel tabs in caps | once daily | |
| Tiazac
(Forest) |
120mg, 180mg, 240mg, 300mg, 360mg, 420mg | ext-rel caps | ext-rel beads in caps | once daily | |
| DIHYDROPYRIDINES | |||||
| AMLODIPINE | Norvasc
(Pfizer) |
2.5mg, 5mg, 10mg | tabs | tabs | once daily |
| Combination | Lotrel*
(Novartis) |
2.5/10, 5/10, 5/20, 5/40, 10/20, 10/40
(mg amlodipine/mg benazepril) |
combination caps | caps | titrate |
| FELODIPINE | Plendil
(AstraZeneca) |
2.5mg, 5mg, 10mg | ext-rel tabs | hydrophilic gel | once daily |
| ISRADIPINE | DynaCirc CR
(GSK) |
5mg, 10mg | controlled-rel tabs | osmotic pump | once daily |
| NICARDIPINE | Nicardipine
(various) |
20mg, 30mg | caps | caps | three times daily |
| Cardene SR
(PDL Pharma) |
30mg, 45mg, 60mg | sust-rel caps | encapsulated beads within capsule | twice daily | |
| NIFEDIPINE | Adalat CC
(Bayer) |
30mg, 60mg, 90mg | ext-rel tabs | slow-release outer coat surrounds fast-release core | once daily |
| Afeditab CR
(Watson) |
30mg, 60mg | ext-rel tabs | ext-rel tabs | once daily | |
| Procardia XL
(Pfizer) |
30mg, 60mg, 90mg | ext-rel tabs | osmotic pump | once daily | |
| NISOLDIPINE | Sular
(Shionogi) |
8.5mg, 17mg, 25.5mg, 34mg | ext-rel tabs | coat core delivery system | once daily |
| DIPHENYLALKYLAMINES | |||||
| VERAPAMIL | Calan
(Pfizer) |
40mg, 80mg+, 120mg+ | tabs | tabs | three times daily |
| Calan SR
(Pfizer) |
120mg, 180mg+, 240mg+ | sust-rel caplets | sodium alginate matrix | once-twice daily | |
| Covera-HS
(Pfizer) |
180mg, 240mg | ext-rel (controlled onset) tabs | delayed-release osmotic pump | once daily at bedtime | |
| Verelan
(UCB) |
120mg, 180mg, 240mg, 360mg | sust-rel caps | pellet-filled caps | once daily | |
| Verelan PM
(UCB) |
100mg, 200mg, 300mg | ext-rel (controlled onset) caps | polymer-coated beads in caps | once daily at bedtime | |
| Combination | Tarka*
(AbbVie) |
2/180, 1/240, 2/240, 4/240
(mg trandolapril/mg verapamil) |
combination tabs | immediate-release trandolapril and ext-rel verapamil | titrate |
| NOTES | |||||
|
Other products with similar names may be available for different uses. Use care to ensure that the patient receives the appropriate product. For more information see the individual product entries or contact the company marketing the product. Caps = capsules; tabs = tablets; ext-rel = extended-release; sust-rel = sustained release; + = scored. With few exceptions, ext-rel and sust-rel products should not be crushed, chewed, or divided. This is to preserve the products' release characteristics. Regimens shown are from manufacturers' suggested guidelines. Doses should
be individualized.
(Rev. 3/2013) |
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