Ophthalmic Disorders

Beverage Consumption Linked to Lower Glaucoma Odds

December 15, 2017

There were no significant associations between glaucoma and consumption of caffeinated and decaffeinated coffee, iced tea, and soft drinks.

Intraocular Hemorrhage Occurrence for Novel vs. Traditional Antithrombotic Agents

December 14, 2017

The researchers found that the risk of developing an intraocular hemorrhage was reduced with dabigatran or rivaroxaban at 365 days (hazard ratio, 0.75; 95% confidence interval, 0.58 to 0.97; P=0.03) but not at 90 days (hazard ratio, 0.73; 95% confidence interval, 0.22 to 2.63; P=0.13).

Omidria Approved for Use in Pediatric Patients

By December 12, 2017

FDA gave approval following review of efficacy and safety data from a pediatric clinical trial.

Case: Acute Solar Retinopathy After Viewing Eclipse

December 11, 2017

"We have never seen the cellular damage from an eclipse because this event rarely happens and we haven't had this type of advanced technology to examine solar retinopathy until recently," study author Avnish Deobhakta.

FDA Approves Intraocular Lens That Can Be Adjusted Post-Cataract Surgery

By November 27, 2017

First medical device system that can make small adjustments to the artificial lens' power after cataract surgery so that the patient will have better vision when not using glasses.

Clinical Characteristics of Endogenous Endophthalmitis Examined in Injection Drug Users

November 20, 2017

Injection drug users have fewer comorbidities and more improvement in visual acuity after intervention

Soluble Interleukin 2 Receptor Assessed as Biomarker of Sarcoidosis in Uveitis

November 13, 2017

To compare the value of soluble interleukin 2 receptor (sIL-2R) with ACE as diagnostic biomarkers of sarcoidosis in patients with uveitis.

Ranibizumab Plus Dexamethasone vs. Ranibizumab Alone in DME

November 13, 2017

The researchers found that the mean improvement in visual acuity from randomization was 2.7 and 3 letters in the combination and ranibizumab groups, with the adjusted treatment group difference of −0.5 letters.

Experts Pick the Top 10 Medical Innovations for 2018

By November 03, 2017

The panel - made up of nearly 100 physicians and scientists - debated and whittled down over 150 nominations to decide upon the final 10.

Vyzulta Approved to Treat Patients With Open-Angle Glaucoma, Ocular HTN

By November 03, 2017

Vyzulta works by metabolizing into two moieties, latanoprost acid, which primarily works within the uveoscleral pathway to increase aqueous humor outflow, and butanediol mononitrate, which releases NO to increase outflow through the trabecular meshwork and Schlemm's canal.

Bacterial Conjunctivitis Treatments

October 30, 2017

Bacterial conjunctivitis treatment chart for topical medications.

Recall of Two Glaucoma Medications Announced

By October 27, 2017

The recall applies to Combigan 0.2%/0.5% lots in 2.5mL, 5mL, 10mL and 15mL sizes, and one lot of Lumigan 0.01%.

First Gene Tx for Inherited Retinal Disease Gets Thumbs Up from FDA Committee

By October 13, 2017

The recommendation was based on data from the Luxturna clinical development program which included a Phase 3 trial in patients 4-44 years of age.

Glaucoma Treatments

October 13, 2017

Glaucoma treatment chart (alpha2-agonists, beta blockers, carbonic anhydrase inhibitors, cholinergic agonists, prostaglandin analogs).

Do Electronic Health Records Present Increased Burden on Ophthalmologists?

October 13, 2017

The researchers found that the mean total ophthalmologist examination time was 11.2 minutes per patient, of which 27% was spent on EHR use, 42% on conversation, and 31% on examination.

Combo Verteporfin Tx Assessed in Polypoidal Choroidal Vasculopathy

October 10, 2017

Mean improvement at 12 months was 8.3 letters with combination therapy compared with 5.1 letters with monotherapy, demonstrating that combination therapy met the predefined criterion for noninferiority as well as being superior to monotherapy.

Vancomycin-Associated HORV Prompts FDA Statement on Intraocular Use

By October 04, 2017

Although not FDA-approved, intraocular vancomycin is often used during cataract surgery to prevent postoperative endophthalmitis.

Infection Risk Investigated for Processed Tissue in Corneal Transplants

October 02, 2017

The researchers found that donor rim culture results were three times more likely to be positive for fungi in endothelial keratoplasty-processed eyes (1.14%) compared with other uses (0.37%).

Dietary Supplement Examined for Effects on Macular Pigment Density

September 29, 2017

The researchers found that there was a statistically significant increase in plasma lutein and zeaxanthin in the lutein plus zeaxanthin group after 3 months and 6 months of treatment versus the placebo group

Zika Associated with Similar Retinal Problems as Cobalamin C Deficiency

September 08, 2017

In 7 of 8 eyes with a normal photoreceptor layer, pericentral retina with normal lamination showed a thinned (<30% of normal thickness) ganglion cell layer (GCL) that colocalized.

USPSTF Issues Vision Screening Recommendation for Children

September 06, 2017

The USPSTF concluded that the overall net benefit is moderate for children aged 3 to 5 years (B recommendation).

Over-the-Counter Tx May Slow Age-Related Macular Degeneration

August 25, 2017

The investigators found that both formulations were cost-effective for treating patients with early-stage disease, but they were even more cost-effective for those with the condition in only 1 eye.

The Dos and Don'ts of Viewing a Solar Eclipse

By August 18, 2017

The moon passes the sun so quickly (at 2880km/h) that most of the time individuals (even those in the direct path of totality) will be experiencing a partial eclipse, and will be exposed to the sun's core.

FDA: Vision Impairment, Other Serious Side Effects Tied to Compounded Injectable

By July 31, 2017

The triamcinolone and moxifloxacin injection was intended for use as post-op prophylaxis for ocular inflammation and endophthalmitis to eliminate the use of post-op eye drops.

Eye Exams Should Be Requirement for Infants Potentially Exposed to Zika

July 18, 2017

One in 5 of the infants had sight-threatening eye abnormalities, with optic nerve and retinal abnormalities the most common.

Rohto Dry-Aid Now Available for Dry Eye Relief

By July 12, 2017

The micro-emulsion contains povidone 0.68% and propylene glycol 0.3%, which work by mimicking a natural tear to restore moisture to the tear film for up to 12 hours.

Early Biomarker May Help Differentiate Parkinsonism Disorders

July 12, 2017

Magnetic resonance imaging (T1-weighted and diffusion-weighted imaging) with a 3-T magnetic resonance imager revealed that the Parkinson's patients had significant alterations in optic radiation connectivity distribution.

Refresh Optive Mega-3 Available for Dry Eye Relief

By June 27, 2017

All Optive products have the patented osmoprotectant formula comprised of three solutes: glycerin, I-carnitine, and erythritol.

NDA Accepted for Anti-Inflammatory Inj Post-Cataract Surgery

By June 26, 2017

Dexycu injection was developed to help compliance—especially among elderly patients—and avoid dosing errors associated with conventional treatments that depend on self-administered eye drops multiple times a day.

Clinicians Overprescribing Antibiotics for Common Eye Infection

By June 19, 2017

Fifty-eight percent (n=198,462) of the total patients had filled ≥1 topical antibiotic prescription, of which approximately 20% (n=38,774) of patients filled prescriptions for combination antibiotic + corticosteroid products.