The moon passes the sun so quickly (at 2880km/h) that most of the time individuals (even those in the direct path of totality) will be experiencing a partial eclipse, and will be exposed to the sun's core.
The triamcinolone and moxifloxacin injection was intended for use as post-op prophylaxis for ocular inflammation and endophthalmitis to eliminate the use of post-op eye drops.
One in 5 of the infants had sight-threatening eye abnormalities, with optic nerve and retinal abnormalities the most common.
The micro-emulsion contains povidone 0.68% and propylene glycol 0.3%, which work by mimicking a natural tear to restore moisture to the tear film for up to 12 hours.
Magnetic resonance imaging (T1-weighted and diffusion-weighted imaging) with a 3-T magnetic resonance imager revealed that the Parkinson's patients had significant alterations in optic radiation connectivity distribution.
Dexycu injection was developed to help compliance—especially among elderly patients—and avoid dosing errors associated with conventional treatments that depend on self-administered eye drops multiple times a day.
Fifty-eight percent (n=198,462) of the total patients had filled ≥1 topical antibiotic prescription, of which approximately 20% (n=38,774) of patients filled prescriptions for combination antibiotic + corticosteroid products.
After adjustment for potential confounders, the risk of cataracts was lower among participants in the highest versus the lowest tertile of dietary vitamin K1 intake (hazard ratio, 0.71).
The FDA has completed its initial 60-day review of the New Drug Application (NDA) for Rhopressa (netarsudil; Aerie) 0.02% and determined that it's sufficiently complete to permit a substantive review.
Smith, TJ et al. "Teprotumumab for Thyroid-Associated Ophthalmopathy". DOI: 10.1056/NEJMoa1614949.
The researchers found that in the intention-to-treat population, 69 and 20% of those who received teprotumumab and placebo, respectively, had a response at week 24.
Researchers conducted a secondary analysis of data from a comparative effectiveness trial for center-involved DME in 650 participants during 2 years of treatment with aflibercept (2mg), bevacizumab (1.25mg), or ranibizumab (0.3mg).
Children with active JIA-associated uveitis who were taking a stable dose of methotrexate were randomly assigned to either adalimumab or placebo for 2 weeks.
Safety and efficacy of the TrueTear device were demonstrated in two clinical studies in a total of 145 individuals with aqueous deficient dry eye.
The researchers observed an increase in cone-like cells after switching rod to cone-like photoreceptors in situ by inactivation of Nrl or Nr2e3.
The analysis indicated that patients with and without DME in the Lucentis treatment group had improvements in the severity of their retinopathy.
Dexycu is a long-acting, biodegradable extended-release formulation of the anti-inflammatory agent dexamethasone, which is injected into the anterior chamber of the eye following cataract surgery.
The researchers assessed the cardiovascular and cerebrovascular safety of ranibizumab 0.3mg and 0.5mg vs. sham with and without laser in diabetic macular edema.
A comparative dosing chart of prescription and over-the-counter (OTC) medications for allergic conjunctivitis treatment.
The researchers found that early AMD was associated with a small reduction in VSF compared with no AMD in adjusted models in a group of ethnic Chinese but not in groups of ethnic Indians or Malays.
The finished product is still some way off being consumer-ready, but when complete it could restore sight to millions of people with degenerative eye diseases.
Restasis, a calcineurin inhibitor immunosuppressant, helps increase the eyes' natural ability to produce tears in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.
Compared with the placebo group, the ω-3 EFA group had a greater reduction in Ocular Surface Disease Index score and tear osmolarity at day 90 versus baseline.