Ophthalmic Disorders

The Dos and Don'ts of Viewing a Solar Eclipse

By August 18, 2017

The moon passes the sun so quickly (at 2880km/h) that most of the time individuals (even those in the direct path of totality) will be experiencing a partial eclipse, and will be exposed to the sun's core.

FDA: Vision Impairment, Other Serious Side Effects Tied to Compounded Injectable

By July 31, 2017

The triamcinolone and moxifloxacin injection was intended for use as post-op prophylaxis for ocular inflammation and endophthalmitis to eliminate the use of post-op eye drops.

Eye Exams Should Be Requirement for Infants Potentially Exposed to Zika

July 18, 2017

One in 5 of the infants had sight-threatening eye abnormalities, with optic nerve and retinal abnormalities the most common.

Rohto Dry-Aid Now Available for Dry Eye Relief

By July 12, 2017

The micro-emulsion contains povidone 0.68% and propylene glycol 0.3%, which work by mimicking a natural tear to restore moisture to the tear film for up to 12 hours.

Early Biomarker May Help Differentiate Parkinsonism Disorders

July 12, 2017

Magnetic resonance imaging (T1-weighted and diffusion-weighted imaging) with a 3-T magnetic resonance imager revealed that the Parkinson's patients had significant alterations in optic radiation connectivity distribution.

Refresh Optive Mega-3 Available for Dry Eye Relief

By June 27, 2017

All Optive products have the patented osmoprotectant formula comprised of three solutes: glycerin, I-carnitine, and erythritol.

NDA Accepted for Anti-Inflammatory Inj Post-Cataract Surgery

By June 26, 2017

Dexycu injection was developed to help compliance—especially among elderly patients—and avoid dosing errors associated with conventional treatments that depend on self-administered eye drops multiple times a day.

Clinicians Overprescribing Antibiotics for Common Eye Infection

By June 19, 2017

Fifty-eight percent (n=198,462) of the total patients had filled ≥1 topical antibiotic prescription, of which approximately 20% (n=38,774) of patients filled prescriptions for combination antibiotic + corticosteroid products.

FDA Approves Zerviate for Allergic Conjunctivitis

By June 01, 2017

Zerviate is the first topical ocular formulation of cetirizine.

Roclatan Meets Primary Endpoint in Phase 3 Glaucoma Study

By May 24, 2017

The evaluation of Roclatan has been ongoing in two distinct trials.

Can Dietary Vitamin K Protect Against Cataracts?

May 22, 2017

After adjustment for potential confounders, the risk of cataracts was lower among participants in the highest versus the lowest tertile of dietary vitamin K1 intake (hazard ratio, 0.71).

FDA Accepts NDA for Glaucoma Drug Rhopressa

By May 15, 2017

The FDA has completed its initial 60-day review of the New Drug Application (NDA) for Rhopressa (netarsudil; Aerie) 0.02% and determined that it's sufficiently complete to permit a substantive review.

Implant Compared to Systemic Anti-inflammatory Therapy for Treating Uveitis

May 08, 2017

In seven-year follow-up, visual acuity better than with intravitreous fluocinolone acetonide implants

Teprotumumab for Thyroid-Associated Ophthalmopathy

By May 04, 2017

Smith, TJ et al. "Teprotumumab for Thyroid-Associated Ophthalmopathy". DOI: 10.1056/NEJMoa1614949.

Novel Therapy Shows Potential in Thyroid-Associated Ophthalmopathy

May 04, 2017

The researchers found that in the intention-to-treat population, 69 and 20% of those who received teprotumumab and placebo, respectively, had a response at week 24.

Anti-VEGF Treatments Examined for Effects on Diabetic Retinopathy

April 28, 2017

Researchers conducted a secondary analysis of data from a comparative effectiveness trial for center-involved DME in 650 participants during 2 years of treatment with aflibercept (2mg), bevacizumab (1.25mg), or ranibizumab (0.3mg).

Treatment Combo Shows Promise for JIA-Associated Uveitis

April 27, 2017

Children with active JIA-associated uveitis who were taking a stable dose of methotrexate were randomly assigned to either adalimumab or placebo for 2 weeks.

Novel Tear Production Stimulator Given All Clear by FDA

By April 25, 2017

Safety and efficacy of the TrueTear device were demonstrated in two clinical studies in a total of 145 individuals with aqueous deficient dry eye.

Novel Therapy Shows Promise in Retinitis Pigmentosa

April 25, 2017

The researchers observed an increase in cone-like cells after switching rod to cone-like photoreceptors in situ by inactivation of Nrl or Nr2e3.

FDA Approves Treatment for All Forms of Diabetic Retinopathy

By April 17, 2017

The analysis indicated that patients with and without DME in the Lucentis treatment group had improvements in the severity of their retinopathy.

NDA Submitted for Post-Cataract Surgery Inflammation Treatment

By April 13, 2017

Dexycu is a long-acting, biodegradable extended-release formulation of the anti-inflammatory agent dexamethasone, which is injected into the anterior chamber of the eye following cataract surgery.

Recreational 'Poppers' Linked to Blurriness and Blind Spots

April 12, 2017

The 6 products with isopropyl nitrite were associated with visual problems while the 2 without were not.

Cardio-, Cerebrovascular Safety of Ranibizumab in DME Evaluated

April 10, 2017

The researchers assessed the cardiovascular and cerebrovascular safety of ranibizumab 0.3mg and 0.5mg vs. sham with and without laser in diabetic macular edema.

Allergic Conjunctivitis Treatments

April 10, 2017

A comparative dosing chart of prescription and over-the-counter (OTC) medications for allergic conjunctivitis treatment.

Impact of Age-Related Macular Degeneration May Differ by Ethnicity

March 31, 2017

The researchers found that early AMD was associated with a small reduction in VSF compared with no AMD in adjusted models in a group of ethnic Chinese but not in groups of ethnic Indians or Malays.

Implantable Artificial Retina in the Works

By March 29, 2017

The finished product is still some way off being consumer-ready, but when complete it could restore sight to millions of people with degenerative eye diseases.

Chronic Dry Eye Med Available in Preservative-Free, Multidose Form

By March 22, 2017

Restasis, a calcineurin inhibitor immunosuppressant, helps increase the eyes' natural ability to produce tears in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.

Supplement May Protect Corneal Nerves In Dry Eye

March 21, 2017

Compared with the placebo group, the ω-3 EFA group had a greater reduction in Ocular Surface Disease Index score and tear osmolarity at day 90 versus baseline.

Tocilizumab Assessed for JIA-Associated Uveitis

March 17, 2017

Rapid and maintained improvement in all ocular parameters was seen with tocilizumab treatment.

Stem Cell Therapy for AMD Appears Beneficial but Risky

March 16, 2017

One report warns of severe visual loss after macular degeneration treatment in 'trial'