Generic Name for OMNISCAN
Gadodiamide 287mg/mL; soln for IV inj.
Legal Classification:
Rx
Pharmacological Class for OMNISCAN
Gadolinium-based contrast agent.
Manufacturer of OMNISCAN
GE Healthcare
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Indications for OMNISCAN
For use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues. For use in MRI to facilitate the visualization of lesions with abnormal vascularity within the thoracic (noncardiac), abdominal, pelvic cavities, and the retroperitoneal space.
Adult dose for OMNISCAN
CNS: 0.2mL/kg given as a bolus IV inj. An additional 0.4mL/kg can be given within 20 minutes of the first dose. Kidney: 0.1mL/kg. Intrathoracic (noncardiac), intra-abdominal, pelvic cavities: 0.2mL/kg.
Children's dosing for OMNISCAN
CNS: 2–16yrs: 0.2mL/kg given as a bolus IV inj. Kidney: 0.1mL/kg. Intrathoracic (noncardiac), intra-abdominal, pelvic cavities: 0.2mL/kg.
Warnings/Precautions for OMNISCAN
Not for intrathecal use; may cause convulsions, coma, sensory and motor neurologic deficits. Increased risk of nephrogenic systemic fibrosis among patients with acute or chronic renal impairment (GFR<30mL/min/1.73m2) and in patients with acute renal insufficiency of any severity due to hepato-renal syndrome or in perioperative liver transplantation period. Screen for renal dysfunction. Acute renal failure possible in patients with renal insufficiency within 48hrs of injection; use lowest possible dose and evaluate renal function. Do not exceed recommended dose; allow sufficient period of time for elimination prior to re-administration. History of asthma/allergy disorders. Anaphylactoid reactions possible; have emergency equipment available. Pregnancy (Cat.C). Nursing mothers.
Interactions for OMNISCAN
Interferes with serum calcium measurements with some colorimetric methods.
Adverse Reactions for OMNISCAN
Nausea, headache, dizziness; cardiac failure, arrhythmia, MI.
How is OMNISCAN supplied?
Vials (10mL, 15mL, 20mL)—10; Prefilled syringe (15mL, 20mL)—10; Prefill Plus needle-free system (15mL, 20mL)—10 (prefilled syringe + sodium chloride 0.9% inj flush syringe)