First Male Contraceptive Injection to Undergo Testing in 2015

Vasalgel, the first male contraceptive injection, is anticipated to enter its first clinical trial beginning in 2015, according to the Parsemus Foundation.

Early Preeclampsia Detection Test Under Development

DiabetOmics announced a new point-of-care test to detect preeclampsia, assess the severity of the disease, and monitor its complications in as early as the 1st trimester.

Combination Ovarian Cancer Therapy Granted Fast Track Status

The Food and Drug Administration (FDA) has granted Fast Track designation to motolimod (VTX-2337; VentiRx) in combination with pegylated liposomal doxorubicin (PLD) for the treatment of women with ovarian cancer whose disease has progressed on or recurred after platinum-based chemotherapy.

New Prenatal Test ID's Multiple Chromosomal Abnormalities

LabCorp announced the launch of the informaSeq Prenatal Test, a non-invasive prenatal screening assay that can assess for multiple fetal chromosomal aneuploidies, or abnormalities in the number of chromosomes from a single maternal blood draw.

Palbociclib NDA Submitted for Advanced Breast Cancer

Pfizer announced that it has submitted an NDA to the FDA for palbociclib in combination with letrozole for the treatment of postmenopausal women with estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer who have not received previous systemic treatment for the advanced disease.

Avastin Gains New Indication for Metastatic Cervical Cancer

Genentech has announced that the Food and Drug Administration (FDA) has approved Avastin (bevacizumab) in combination with paclitaxel and cisplatin or paclitaxel and topotecan for the treatment of women with persistent, recurrent, or metastatic cervical cancer.

Similac Launches Breastfeeding Supplement for Nursing Mothers

A new Similac breastfeeding supplement is specially designed to enhance the levels of DHA, lutein, and vitamin E in breastmilk.

Neratinib Demonstrates Potential in Breast Cancer Trial

Puma Biotechnology announced results from its Phase 3 ExteNET trial of neratinib (PB272) for the extended adjuvant treatment of breast cancer.

FDA Accepts sBLA, Grants Priority Review for Avastin in Ovarian Cancer

The FDA grants Genentech's sBLA for Avastin (bevacizumab) plus chemotherapy Priority Review for the treatment of women with recurrent platinum-resistant ovarian cancer.

Priority Review, sBLA Granted for Cervical Cancer Tx

The FDA has accepted Genentech's supplemental Biologics License Application (sBLA) and granted Priority Review for Avastin (bevacizumab) plus chemotherapy for the treatment of women with persistent, recurrent or metastatic cervical cancer.

Monistat Introduces Complete Care Products Line

Monistat announced the launch of Monistat Complete Care products, which include a vaginal health test, probiotics, and an odor-neutralizing gel.

More Fish for Pregnant, Breastfeeding Women, Says FDA

The Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) issued draft updated advice regarding the consumption of fish by pregnant and breastfeeding women and young children.

Novel PCOS Drug Granted Orphan Status

EffRx announced that the FDA has granted orphan drug designation to EX404 for the treatment of pediatric polycystic ovary syndrome (PCOS).

Chewable Prenatal Vitamins Reformulated

TherapeuticsMD announced the launch of newly reformulated vitaMedMD RediChew Rx, a branded prescription prenatal vitamin, and Prena1 Chew, a generic prescription prenatal vitamin.

High Cholesterol to Blame for Infertility?

For couples trying to conceive, high cholesterol levels may impair fertility according to a recent study published in the journal JECM.

Over Two-Thirds of U.S. Infected with HPV

A new study has found that 69% percent of healthy American adults are infected with one or more of 109 strains of the human papillomavirus (HPV).

Women More Likely Than Men to Skip Tests, Rxs, Says Survey

The 2013 Kaiser Women's Health Survey results showed how women and their health care and coverage were impacted during the Affordable Care Act (ACA) transition.

NCHS: More Older Women Having First Births

Over the past 40 years, the average age of women having first births has risen, according to a report from the National Center for Health Statistics (NCHS).

New Preconception Test to Detect Vaginal Infections

e.p.t. announced the launch of its Preconception Health Test, a new test that measures vaginal acidity and indicates the presence of infections so women can seek treatment before trying to conceive.

Gestational Diabetes Risk Linked to Liver Enzyme

Compared to women with the lowest levels, women with high levels of a common liver enzyme prior to pregnancy are twice as likely to subsequently develop gestational diabetes.

FDA Proposes Transvaginal Mesh Device Reclassification

The FDA has issued two proposed orders regarding surgical mesh used for transvaginal repair of pelvic organ prolapse (POP) and health risks associated with this product.

First Guidelines for Managing Fetal Heart Abnormalities

The American Heart Association has released the first scientific statement on current and recommended practices of diagnosis and management of fetal cardiac disease.

First HPV Test for Primary Cervical Cancer Approved

The FDA has approved Roche's cobas HPV Test, the first human papillomavirus (HPV) DNA test for women ages >25 that can be used alone to help assess the need for additional diagnostic testing for cervical cancer.

FDA Discourages Laparoscopic Power Morcellation in Hysterectomy, Myomectomy

The FDA is discouraging the use of laparoscopic power morcellation for the removal of the uterus or uterine fibroids in women based on a recent analysis of currently available data.

New Less Invasive Vulvar Cancer Treatment Technique Possible

Sentinel lymph node dissection in women with vulvar malignancies allowed gynecologic oncology surgeons to identify and remove just the sentinel nodes and follow the patients for complications and recurrence.

Gene Variant Discovered in PCOS

The variant in the gene DENND1A has been identified as a likely stimulant for the overproduction of androgen in women with polycystic ovary syndrome (PCOS).

Low Dose Aspirin Does Not Reduce Pregnancy Loss

The National Institutes of Health (NIH) reported that daily low dose aspirin therapy did not improve birth rates in most women with prior history of one or more pregnancy losses.

Non-Ob-Gyns Deliver ~14 Percent of Routine Prenatal Care

Non-Ob-Gyn providers delivered one out of every seven routine prenatal care visits in the United States in 2009-2010.

FDA Approves Combo IVF Drugs for Infertility

Ferring Pharmaceuticals announced that the FDA has approved a new labeling for Menopur (menotropins for injection) and Bravelle (urofollitropin for injection) stating that both products can be safely mixed and administered in a single injection.

Lower HPV Uptake for Women in UK Sexual Health Services

For young women attending sexual health services in England, HPV vaccination uptake and completion rates are lower than national data.

Haemophilus Influenzae Infection Up in Pregnancy

The incidence of Haemophilus influenzae infection is increased during pregnancy, and infection correlates with poor pregnancy outcomes.

Smallest Prenatal Vitamin Now Available

TherapeuticsMD, Inc. (parent company of vitaMedMD, LLC) announced the launch of vitaPearl, the latest addition to the vitaMedMD prenatal multivitamin line.

Nicotine Patches Effective for Pregnant Smokers?

Use of nicotine patches, compared with placebo patches, does not increase the smoking cessation rate among pregnant women.

Gestational Diabetes Ups Risk of Early Atherosclerosis

Among women who have not developed diabetes or metabolic syndrome, a history of gestational diabetes mellitus (GDM) may be a marker for early atherosclerosis.

FDA Panel Recommends HPV Test As Replacement for Pap

A U.S. FDA advisory panel voted unanimously on Wednesday that a new HPV test could be used before or instead of the Pap smear as a first step in cervical cancer screening

Research Supports Alcohol Abstinence Advice Pre-Conception

Women who consume alcohol before pregnancy and during the first two trimesters are at increased risk for adverse pregnancy outcomes.

FDA Experts Debate Timing of Pap Test

A U.S. Food and Drug Administration advisory panel is considering whether to delay the Pap test and use an human papillomavirus (HPV) test as a first step in cervical cancer screening.

Low Birth Weight, SGA Linked to Female Fertility

For women born with low birth weight or small for gestational age, the odds of female-related infertility are increased.

Fewer Failures With Vaginal Mesh Repair in Prolapse With Avulsion

For women with vaginal prolapse after hysterectomy and levator ani avulsion, Prolift Total is associated with a lower anatomical failure rate than unilateral vaginal sacrospinous colpopexy with native tissue vaginal repair (sacrospinous fixation).

Transvaginal Approaches for Vaginal Prolapse

For women undergoing surgery for vaginal prolapse and stress urinary incontinence, outcomes for two common transvaginal approaches are comparable, and perioperative behavioral therapy with pelvic floor muscle training does not improve surgical outcomes

Diets May Cut Preterm Delivery Risk

Following a "prudent" or "traditional" diet is associated with a reduced risk of preterm delivery.

Yoga May Improve Menopausal Quality of Life

Yoga may improve menopause-related quality of life (QOL) in women with vasomotor symptoms.

Frameshift Mutation Identified in Premature Ovarian Failure

A frameshift mutation in a gene encoding a cohesin subunit has been identified in a large consanguineous family with premature ovarian failure.

HPV Vaccine Protects Against Cervical Abnormalities

The human papillomavirus (HPV) vaccine is effective at protecting against cervical abnormalities in young women.

Pregnancy Timing Affected by Male Phthalate Levels

High concentrations of three common forms of phthalates in men have been shown to impact fertility in couples trying to conceive.

Globulin Tied to Gestational Diabetes Risk

Low prepregnancy sex hormone-binding globulin (SHBG) concentrations correlate with increased risk of gestational diabetes mellitus.

CDC: Trends in Out-of-Hospital Births

The percentage of out-of-hospital births is continuing to increase, and in 2012 these births had a lower risk profile than hospital births.

Ordering Procedures Change Postpartum Pertussis Vaccination Rates

Changing in-hospital ordering procedures increases the postpartum pertussis vaccination rate to 69%.

Smoking, Smoke Exposure Impact Pregnancy Outcomes

Women who were ever smokers during their reproductive years and those never-smoking women with the highest levels of secondhand smoke exposure have significantly increased odds for spontaneous abortion, stillbirth, and tubal ectopic pregnancy.

Hormonal Contraceptives May Increase MS Risk

Use of hormonal contraceptives may be contributing to the increasing incidence of MS in women.

Fertility Concerns for Young Women With Breast CA

Fertility concerns are common among young women with newly diagnosed breast cancer, although only a minority pursue fertility preservation strategies.

Prenatal DNA Test Bests Standard Screening in General Population

Maternal plasma cell-free DNA (cfDNA) sequencing for trisomies 18 and 21 gives 5-10 fold higher positive predictive values than standard aneuploidy screening.

In-Hospital Formula Impacts Breastfeeding

Use of supplementation with in-hospital formula shortens the duration of breastfeeding among first-time mothers who intend to breastfeed exclusively

Hysterectomy, Ovary Removal Linked to Diabetes

Postmenopausal women are at higher risk of developing diabetes if they have both a hysterectomy and bilateral oophorectomy.

Acetaminophen Use in Pregnancy May Up Risk for Child's ADHD

Children whose mothers took acetaminophen during pregnancy are at a higher risk for developing hyperkinetic disorders (HKDs) and attention-deficit/hyperactivity disorder (ADHD)-like behavioral problems.

HPV Vaccination Impacts Lesion Risk

Vaccination with the quadrivalent HPV vaccine is associated with reduced risk of atypia or worse (atypia+) or cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3).

Fever During Pregnancy Associated With Birth Defects

Fever during pregnancy is associated with adverse health outcomes for the offspring.

FDA Panel to Review Oocyte Modification Therapy

An FDA panel will review information on mitochondrial manipulation to prevent mitochondrial diseases and to treat infertility.

Preventive Pediatric Health Care Recommendations Updated

Recommendations for preventive pediatric health care have been updated, according to an American Association of Pediatrics (AAP) policy statement.

Obstetricians Target Primary Cesarean Delivery Rate

Primary cesarean delivery rates can be safely reduced by implementing various interventions, according to an ACOG consensus statement.

Intensive Dialysis Improves Pregnancy Outcomes

For women with end-stage renal disease (ESRD), intensive hemodialysis is associated with improved pregnancy outcomes.

Total Vaginal Hysterectomy Generates Net Hospital Income

Compared with total vaginal hysterectomy (TVH), hospital costs are greater with laparoscopic assisted vaginal hysterectomy (LAVH), total laparoscopic hysterectomy (TLH), and robotic hysterectomy (RH).

Prenatal Vitamin A Deficiency May Contribute to Asthma

Early fetal retinoic acid (RA) deficiency is associated with altered airway smooth muscle phenotype, with RA restricting airway smooth muscle differentiation.

Women and Opioid Rx During Pregnancy

Opioids are fairly commonly dispensed during pregnancy, with 14.4% of women dispensed an opioid at some point during pregnancy.

Research Supports Dangers of Drinking in Early Pregnancy

Drinking moderate to large amounts of alcohol early in pregnancy may damage the placenta and reduce the amount of taurine delivered to the fetus from the mother.

Paper Gestational Age Wheels Generally Inaccurate

Paper wheels are inaccurate for estimating date of confinement, according to a recent study.

Genes, Smoking Tied to Early Menopause in Whites

Women of European descent are at greater risk of entering menopause early if they smoke and carry particular gene variants.

Moderate Physical Activity Cuts Stroke Risk in Women

For women, moderate to strenuous physical activity is associated with a decreased risk of stroke, even among those using postmenopausal hormone therapy.

Stellate Ganglion Blockade Cuts Menopause Symptoms

For postmenopausal women, stellate ganglion blockade (SGB) significantly reduces objective measures of vasomotor symptoms (VMS).

Many Women Do Not Attend Post-Delivery Follow-Up Visits

Many women do not attend recommended follow-up primary care visits after delivering a child.

Postpartum Thrombosis Risk Lasts for at Least 12 Weeks

For postpartum women, the risk of thrombosis is elevated for at least 12 weeks after delivery.

Gestational Age Inversely Linked to Insulin Levels at Birth

Gestational age is inversely associated with insulin levels at birth, according to a study recently published.

Fertility Rates About Three Times Higher in Mentally Ill Teens

Adolescent girls with major mental illness have nearly three-fold increased age-specific fertility rates, compared with unaffected girls.

Talking to Preemies in NICU Benefits Cognition, Language

For preterm infants, adult word count in the neonatal intensive care unit (NICU) correlates positively with cognitive and language development.

HPV Vaccines Don't Change Behaviors in Young Women

Young women do not engage in riskier sexual behaviors following human papillomavirus (HPV) vaccination regardless of their risk perceptions.

Study Quantifies Epidural-Linked Increase in 2nd Stage of Labor

The second stage of labor is significantly longer for both nulliparous and multiparous women receiving an epidural.

NSAID Exposure Not Linked to Risk of Spontaneous Abortion

Fetal nonsteroidal anti-inflammatory drug (NSAID) exposure is not an independent risk factor for spontaneous abortion.

IVF and Genetic Testing Used to Avoid Prion Disease

In vitro fertilization (IVF) and genetic testing have been used to allow a woman with a family history of a prion disease to have healthy twins lacking the mutation.

Increased Neonatal Mortality Rates for Home Births

Despite a higher neonatal mortality rate, home births have increased over the past decade, and the increased risk is associated with the location of a planned birth, rather than the credentials of the person delivering the baby.

Major Congenital Anomaly Risk Down for Older Moms

Advanced maternal age is associated with decreased risk for major fetal congenital anomalies.

Postmenopausal Hormone Rx May Cut Risk for Glaucoma

Use of estrogen-only postmenopausal hormone (PMH) treatment may help reduce the risk for primary open-angle glaucoma (POAG).

Preterm Birth Tied to Increased Risk of Childhood Wheeze

Preterm birth, especially very preterm birth, is associated with an increased risk of childhood wheezing disorders.

High Estradiol Levels Linked to Dementia in Women

Postmenopausal women with high estradiol levels have a two-fold higher risk of developing dementia, but the risk is 14-fold higher if they also have diabetes.

Fear of Violence Hinders Women's Attempts at Safer Sex

Women who fear intimate partner violence (IPV) report inconsistent condom use and difficulty in negotiating safer sex.

Hormone Therapy Linked to Arthroplasty Revision

Hormone replacement therapy use (HRT) is associated with a reduction in revision rates for total knee arthroplasty (TKA) and total hip arthroplasty (THA).

Postpartum Depression Often Becomes Chronic

Postpartum depression can become chronic in 30 to 50 percent of women with the condition.

CDC: Cesarean Section Rate Declining in the United States

Cesarean section rate increased then decreased between 2006 and 2012.

CDC: Use of Infertility Services Declining in the United States

Anjani Chandra, PhD, and colleagues, analyzed data on the use of infertility services from 22,682 interviews with men and women.

Higher Omega-3 Levels Linked to Larger Brain Volume

A higher omega-3 index is associated with increased brain and hippocampal volume eight years later in postmenopausal women.

Prenate Enhance and Prenate Restore Launched

Avion announced the addition of two new vitamin formulations to the Prenate Vitamin line: Prenate Enhance and Prenate Restore.

USPSTF Recommends GDM Screening After 24 Weeks

The U.S. Preventive Services Task Force (USPSTF) recommends screening asymptomatic pregnant women for gestational diabetes mellitus (GDM) after 24 weeks of gestation.

Risk Factors Identified for Incidence of Vulvodynia

The incidence of vulvodynia varies with age, ethnicity, and marital status, and is associated with previous symptoms or intermediate symptoms not meeting criteria for vulvodynia.

Breastfeeding Linked to Reduced RA Risk in Chinese Women

For women from South China, breastfeeding is associated with reduced risk of rheumatoid arthritis (RA), especially a longer duration of breastfeeding.

Conventional Vs. Intensive T1DM Tx Not Tied to Menopause

For women with type 1 diabetes, intensive vs. conventional treatment is not associated with menopause risk, although greater insulin dose is associated with lower natural menopause risk.

Guideline Adherence Cuts Cancer Risk in Postmenopausal Women

All-cause and cancer-specific mortality is lower in postmenopausal women who follow the American Cancer Society (ACS) Nutrition and Physical Activity Cancer Prevention Guidelines.

Preemie Crying Linked to Later Behavioral Problems

Early crying in preterm infants is associated with later child behavioral problems, and an education program can reduce postnatal depression symptoms as well as infant sleep and cry problems.

Risks Associated With Early-Term Delivery Highlighted

Non-medically indicated early-term delivery is associated with increased neonatal morbidity and mortality, and interventions to reduce these deliveries are encouraged.

Obama Administration Stands by Contraception Rule

The Obama administration on Friday contested U.S. Supreme Court Justice Sonia Sotomayor's decision temporarily exempting an order of Catholic nuns from the Affordable Care Act's contraception mandate.

Guidelines for Management of Menopausal Symptoms Issued

Evidence-based treatment guidelines for menopause management include personalizing treatment for optimal symptom relief.

One-Third of Teen Health Visits Don't Mention Sexuality

About one-third of adolescents have annual health maintenance visits without any mention of sexuality.

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