During the highest dose of glucose infusion, the GB subjects had relative hyperglycemia associated with significantly reduced β-cell glucose sensitivity throughout both step-up
The researchers found that the mean weight loss was 38.2kg or 28.4% of baseline weight at 7 years after RYGB; mean weight regain was 3.9% between years 3 and 7.
Data were included for 3,310 patients with HFpEF: 2,413 with abdominal obesity and 897 patients without abdominal obesity.
The researchers found that in murine primary adipocytes, CA significantly activated PKA signaling, increased expression levels of thermogenic genes, and induced phosphorylation of hormone-sensitive lipase and protein perilipin 1.
The researchers found that LGB was associated with a greater drop in BMI. In intention-to-treat analyses, the effective apnea-hypopnea index (AHI) at nine months was 29.5 and 20 events/hour in the LGB and CPAP groups, respectively (P=0.02), while at 18 months, the effective AHI was 20.9 and 21.4 events/hour, respectively.
After Roux-en-Y, CNS activation reduced in response to food cues, GLP-1 levels significantly elevated We hypothesized that postoperative elevated GLP-1 levels contribute to the improved satiety regulation after RYGB via effects on the CNS.
The researchers found that, compared with placebo, probiotic administration resulted in a significantly larger reduction in body weight, BMI, and fat percentage.
Researchers aimed to determine whether the rise in prescription drug use over time varied by age and obesity status.
The researchers found that the mean reduction measured by skin fold caliper was 33% (3.2 mm; P=0.05), and by magnetic resonance imaging, the mean reduction was 1.78mm.
The researchers found that the adjusted mean changes from baseline in body weight in the surgery group were −45.0, −36.3, and −35.0 kg at 2, 6, and 12 years, respectively.
BMI was positively correlated with ER+/PR+ and ER−/PR− subtype risks, with a significant association only seen for ER+/PR+ subtypes.
The patches mechanism of action turns white adipose tissue into brown adipose tissue, white tissue is known to store fat while brown tissue is known to burn fat to produce heat.
The postprandial glucose nadir was increased by 66%, peak insulin was reduced by 57%, and neuroglycopenic symptoms were reduced by 80%, on average.
The researchers found that for religious affiliation there were significant associations with body weight in both cross-sectional and longitudinal studies.
In both studies, more participants on LDX versus placebo were categorized as improved on the Clinical Global Impressions-Improvement starting at week one.
Traditional methods of measuring weight or body mass index are ineffective in assessing whether a person is overfat, the study authors said.
The researchers found that off-treatment ARU was significantly reduced post-bariatric surgery versus pre-surgery levels (602±59 versus 531±78; P=0.035).
The investigators found that people who increased their weight by as little as 5% were more likely to have thickening and enlargement of the left ventricle.
The team found that higher sugar-sweetened beverage intake during the second trimester of pregnancy was associated with greater adiposity in mid-childhood.
The researchers assessed the relative risk for influenza and ILI on the basis of body mass index and determined seroconversion and seroprotection rates using pre-vaccination and 26-35 day post-vaccination serum samples.
At the conclusion of the study period, results showed that the once-daily prebiotic demonstrated significant benefit vs. placebo in change of percent body fat (-2.4% vs. +0.05%) and body weight z-score (-3.1% vs. +0.5%).