Ob/Gyn

Targeting Premenstrual Breakthrough of Depression with OCs: Is it Effective?

By August 18, 2017

Premenstrual exacerbation (PME) of depression has been found to occur in roughly two-thirds of women with depressive disorders.

Can Oral Contraceptives Influence Rheumatoid Arthritis Risk?

August 18, 2017

The researchers found that ever and past OC users had a reduced risk of anticitrullinated protein antibodies (ACPA)-positive RA compared with never users.

Cancer, CV Risks Examined for Vaginal Estrogen Tx in Postmenopausal Women

By August 16, 2017

The data showed women with an intact uterus did not have a significantly different risk of stroke, invasive breast cancer, colorectal cancer, endometrial cancer, and pulmonary embolism/deep vein thrombosis (PE/DVT) between those who used vaginal estrogen and those who did not.

Prenatal Falling Insulin Requirement Linked to Complications

August 16, 2017

The researchers found that FIR ≥15% correlated with an increased risk of the composite primary outcome (odds ratio, 4.38) and preeclampsia (odds ratio, 6.76), and was more common among women with type 1 diabetes (36.6 versus 14.5%)

Smoking Up Among Some Populations During Pregnancy

August 15, 2017

Over the study period, smoking during pregnancy increased significantly among women with MDE (35.9 to 38.4%; P=0.02), while a decreasing trend among women without MDE only approached statistical significance (12.5 to 9.1%; P=0.07).

Does Antiepileptic Drug Use Contribute to Adverse Pregnancy Outcomes?

By August 14, 2017

Women with epilepsy were at increased risk of adverse pregnancy and delivery outcomes.

Cancer Rates Assessed Post-Endometrial Ablation

August 14, 2017

Leiomyomas, age younger than 35 years, at least 2 prior cesarean deliveries, and history of sterilization were factors that predisposed patients to post-ablation hysterectomy.

HIV Viral Load Rebound Observed After Suppression in Pregnancy

August 14, 2017

The researchers found that 318 of the 470 women in the database met inclusion criteria. Nineteen women (6%) had viral load rebound with a mean log10 viral load near delivery of 2.71 copies/mL (=513 copies/mL), while 6 women (32%) had a viral load above 1,000 copies/mL.

Contraindication Added to OCs, Other Ethinyl Estradiol-Containing Drugs

By August 10, 2017

The concomitant use of HCV drug combinations containing ombitasvir, paritaprevir/ritonavir, with or without dasabuvir is contraindicated due to the potential for liver enzyme elevations.

Dimethyl Fumarate and Oral Contraceptives: Drug Interactions Explored

By August 08, 2017

Delayed-release DMF exerts anti-inflammatory and neuroprotective properties for the treatment of relapsing multiple sclerosis, a disease that often develops in women between the ages of 20 and 40.

Drugs Contraindicated in Pregnancy

August 08, 2017

Contraindicated pregnancy medications

Liletta Approved to Prevent Pregnancy for up to Four Years

By August 07, 2017

The FDA's approval of the supplemental New Drug Application (sNDA) was based on efficacy and safety data from the ongoing Phase 3 ACCESS IUS trial.

Neonate Antibody Response Examined After Maternal Flu Vaccination

August 04, 2017

The researchers found that, compared to the 50 women with no vaccination in the previous year, the 91 women vaccinated the prior year exhibited higher baseline antibody titers and/or seroprotection rates against all four influenza strains, after controlling for covariates.

Neonatal Drug Withdrawal Risk Up with In Utero Exposure to Opioids, Psychotropics

August 03, 2017

The researchers observed variation in the absolute risk for neonatal drug withdrawal from 1.0 to 11.4% for infants exposed in utero to prescription opioids alone and opioids co-prescribed with gabapentin, respectively.

ACOG Issues Guidance for Pregnancies Affected by Substance Abuse

July 28, 2017

The authors noted that there may be a select group of women who make an informed choice of medically supervised withdrawal, which should be under the care of an experienced physician and include long-term follow-up and support to help prevent relapse.

ACOG: Recommendations for Counseling Teens About Contraception

July 27, 2017

Ob-gyns should address contraceptive needs, expectations, and concerns, regardless of patient age

Novel Treatment for Dyspareunia Due to Menopause Now Available

By July 24, 2017

Intrarosa contains prasterone, an inactive precursor that is converted locally into estrogens and androgens (with minimal systemic exposure) to help restore vaginal tissue.

Can Estrogen Exposure Affect Depression Risk in Early Post Menopausal Years?

July 24, 2017

Researchers included 1,306 regularly menstruating premenopausal women, aged 42 to 52 years at study entry

Diet, Physical Activity During Pregnancy May Influence C-Section Risk

July 21, 2017

The researchers found that, overall, interventions were associated with a 9% reduction in risk of cesarean section, and a 24% reduction in risk of developing gestational diabetes.

Maternal Antidepressant Use May Contribute to Offspring Autism

July 21, 2017

"Importantly, the absolute risk of autism was small, and, hypothetically, if no pregnant women took antidepressants, the number of cases that could potentially be prevented would be small," wrote the authors of the study.

Ob-Gyn Shortage Possible in Some Parts of the U.S., Says New Report

By July 20, 2017

Commenting on the report, retired Ob-Gyn Valerie Anne Jones, MD said, "Access to maternity care and women's health services is vitally important, and we need to have infrastructure to support the numbers or these women will have no Ob-Gyn to turn to despite having insurance."

Antibiotics During Pregnancy and Birth Defects: What's the Link?

By July 19, 2017

The data showed in utero exposure to clindamycin was associated with a higher risk of MCMs (adjusted odds ratio [aOR] 1.34, 95% CI: 1.02-1.77), musculoskeletal system malformations (aOR 1.67, 95% CI: 1.12-2.48), and ventricular/atrial septal defect (aOR 1.81, 95% CI: 1.04-3.16).

Causes of Pregnancy-Related Death Examined in the United States

July 18, 2017

Increases in pregnancy-related mortality ratios with maternal age, and racial-ethnic disparities persist

Maternal Antidepressant Use and Offspring Disability: What's the Link?

July 13, 2017

No significant association for use of antidepressant in pregnancy, child's intellectual disability

Vitamin D Supplementation Assessed for Preventing Allergic Diseases

July 12, 2017

The researchers found that based on very low certainty in the body of evidence across examined studies, vitamin D supplementation may not reduce the risk of developing allergic diseases.

High Rate of Preeclampsia Underscores Need for New Strategies, Study Finds

July 12, 2017

The findings are particularly important because preeclampsia cases rose from 2.4% of pregnancies in 1980 to 3.8% in 2010, the researchers said.

Sugary Drink Consumption During Pregnancy Tied to Adiposity in Offspring

July 11, 2017

The team found that higher sugar-sweetened beverage intake during the second trimester of pregnancy was associated with greater adiposity in mid-childhood.

WHO: Resistance to Last-Resort Gonorrhea Tx Seen in 66% of Countries

By July 10, 2017

Gonorrhea is a sexually transmitted infection (STI) that can affect the genitals, rectum, and throat. Complications include pelvic inflammatory disease, ectopic pregnancy, infertility, and an increased risk of HIV.

Hormone Replacement Therapies

July 07, 2017

Chart with different formulations and combination of drugs used to treat menopause.

Oral Contraceptives

July 07, 2017

Progestin and estrogen content of oral contraceptives (birth control pills) chart.