Orexigen announced that it has resubmitted an NDA to the FDA for Contrave (naltrexone sustained release [SR]/bupropion SR), an investigational drug for weight loss and maintenance of weight loss.
The FDA has granted a 6-month Priority Review designation to Genzyme's New Drug Application (NDA) for Cerdelga (eliglustat), an investigational oral therapy for adults with Gaucher disease type 1.
Researchers found a higher risk of vitamin B12 deficiency among those who had been dispensed at least a two years' supply of both proton pump inhibitors.
A systematic literature review and meta-analysis showed that healthy food/diet patterns cost more.
Greater body weight satisfaction was associated with greater relationship satisfaction and self-esteem and lower body image self-consciousness.
For extremely obese women, predictors of cesarean delivery (CD) include body mass index (BMI), as well as maternal age, parity, and cervical dilation at the time of admission.
Serum 25-hydroxyvitamin D (25[OH]D) seems to be a marker of ill health and not a causal factor.
Women with GDM had significantly lower serum levels of 25(OH)D than normal pregnant women.
Even metabolically healthy obese are at increased risk of all-cause mortality and/or cardiovascular events.
Higher body mass index (BMI) and larger waist circumference are positively associated, and physical activity is inversely associated, with the risk of self-reported hearing loss.
In those with body mass index (BMI) >29kg/m², a change in awake and fed thermogenesis predicts future weight gain.
High total fiber intake linked to reduced risk; greatest reduction for fiber derived from fruits.
IQ Formulations initiated a precautionary and proactive recall of Hydravax dietary supplement due to a possible undeclared ingredient.
EPA says women may have shifted to eating types of fish with lower mercury concentrations.
In older adults, normal weight obesity (NWO) is associated with cardiac abnormalities and increased risk for cardiovascular mortality.
A 24-month supplementation with a single supplement containing multivitamins and selenium was safe and significantly reduced the risk of immune decline and morbidity in ART-naive HIV-infected adults.
Left gastric artery embolization improves weight loss among patients with upper gastrointestinal bleeding treated with transarterial embolization.
A higher intake of sugar and sugar-sweetened beverages is associated with a higher risk of some endometrial cancers.
Blood pressure, cholesterol, and glucose mediate much of the excess risk of coronary heart disease and stroke associated with high body mass index (BMI).
A systematic review and meta-analysis of observational studies shows that central adiposity, independent of body mass index (BMI), is associated with increased risk of esophageal inflammation, metaplasia, and adenocarcinoma.
Women with symptoms of posttraumatic stress disorder (PTSD) are more likely to become overweight or obese.
In men with prostate cancer, a low-fat fish oil diet is associated with lower serum levels of pro-inflammatory molecules, changes in serum levels of omega fatty acids, and a lower measure of cancer growth, compared with a Western diet.
Researchers find that greater milk consumption during teenage years is not associated with a lower risk of hip fracture in older adults.
The FDA is warning consumers not to purchase or use three products sold for weight loss: Body Beauty 5 Days Slimming Coffee, 1 Day Diet, and Diet Master.
A dose-dependent inverse association between nut consumption and total mortality for women and men was found.
Mean levels of total 25-hydroxyvitamin D and vitamin D-binding protein were significantly lower in blacks than in whites.
The FDA is warning consumers not to purchase or use Slim Max after it was found to contain sibutramine and phenolphthalein.
The FDA notified the public that Fossil Fuel Products and Jobbers Wholesale are voluntarily recalling some sexual enhancement supplements after they were found to contain several undeclared drug ingredients.
Four cases of vitamin K deficiency bleeding (VKDB) have been reported in Tennessee.
For overweight and obese patients with atrial fibrillation, a weight management intervention is associated with reductions in atrial fibrillation symptom burden and severity.
For certain patients, surgical weight loss is associated with increased telomere length.
Women with a history of bariatric surgery are at increased risk for preterm or small-for-gestational-age babies.
Being overweight or obese is a risk factor for myocardial infarction (MI) and ischemic heart disease (IHD) regardless of metabolic syndrome status.
The FDA is warning the public about a potentially harmful counterfeit male sexual enhancement supplement called ExtenZe Maximum Strength.
Non-invasive deep brain stimulation can reduce bingeing and purging in patients with anorexia and bulimia, which correlates with changes in connectivity in particular parts of the brain.
Underweight and obese women were found to more likely to die before 85 years of age, compared to healthy-weight women.
South Asians have lower total brown adipose tissue (BAT) volume than white Caucasians.
The AHA and the ACC released new guidelines on the assessment of cardiovascular risk, lifestyle management to reduce cardiovascular risk, treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults, and the management of overweight and obesity in adults.
Women who indicated interest in breastfeeding at the first prenatal visit were significantly more likely to have the discussion.
Whether or not the non-weight-loss partner adopted new rules and patterns for weight loss management had a substantial impact on communication and behavior within the relationship.
USPlabs LLC is recalling certain OxyElite Pro dietary supplement products after a letter from the FDA stated that the products have been linked to liver illnesses and that there is reasonable probability that the products are adulterated.
Family meals and their related rituals are associated with both child and adult body mass index (BMI).
The FDA is advising consumers not to buy or use Jimpness Beauty Fat Loss Capsules after it was found to contain sibutramine, phenolphthalein, and sildenafil.
The odds of healthy vs. usual aging were 34% greater with increased adherence in midlife to the AHEI-2010 (upper vs. lower quintiles) in midlife.
Concerns about thinness and muscularity in adolescent boys are associated with adverse outcomes.
Women who undergo bariatric surgery to achieve weight loss have significant improvements in sexual function.
For severely obese adults undergoing bariatric surgery, there is considerable weight loss after surgery, and self-reported weight loss seems to be a valid measure of weight loss following bariatric surgery.
Half of severely obese adolescents who undergo weight-loss surgery have several major comorbid conditions, but the short-term safety profile of the surgery is positive.
Increased duration of sleep is associated with lower food intake and lower weight in children.
For children from the Brazilian Amazon, FTO rs9939609 allele is associated with increased body mass index (BMI) and BMI-for-age Z scores, with the effect significantly modified by vitamin D status.
For individuals at high risk of cardiovascular disease, increased consumption of fruits and vegetables has no impact on insulin resistance.
For men with prostate cancer, body mass index (BMI) at diagnosis is associated with mortality.
The risk of autism spectrum disorders (ASD) is increased with maternal prenatal weight gain, but is not associated with pre-pregnancy body mass index (BMI).
Multiple chronic conditions are associated with worse health in terms of activities of daily living and health-related quality of life in older adults.
Research has found that coffee consumption is associated with a lower risk of liver cancer.
Free online games designed to promote branded products are being used to market foods, snacks, and beverages with low nutritional value to young children.
For obese patients, bariatric surgery is associated with greater body weight loss and with higher remission rates of type 2 diabetes and metabolic syndrome compared with non-surgical treatment.
Anti-obesity messages may be encouraging the development of eating disorders.
For patients with pancreatic cancer, higher prediagnostic body mass index (BMI) is associated with decreased survival.
A family pediatrician-led motivational interview was effective in BMI control for overweight children aged 4-7 years.
Recruitment for the first large-scale clinical trial has begun to determine if a vitamin D3 supplement (cholecalciferol) helps prevent or delay type 2 diabetes in adults who have prediabetes.
Human milk purchased over the Internet exhibits high overall bacterial growth and is often contaminated with pathogenic bacteria.
Phentermine and topiramate extended-release treatment plus lifestyle changes lead to significant weight loss and a considerable reduction in progression to type 2 diabetes in high-risk, overweight/obese individuals.
A model taking into account four different factors best predicts mortality with bariatric surgery, while a composite measure best profiles hospital performance of the surgery.
The number of obese adults remained constant at more than 78 million in the United States for 2011 to 2012.
The issues related to calcium supplementation in postmenopausal women are discussed.
Cinnamon supplementation improves menstrual cyclicity and may improve fertility in women with polycystic ovary syndrome (PCOS).
An algorithm has been developed to help physicians navigate medical treatment for obesity care.
Adolescents' weight and socioeconomic status (SES) may affect their subsequent risk of developing esophageal and gastric cancer.
For women in labor, high-protein drink supplementation is associated with improved patient satisfaction compared with ice chips/water.
Overall, six findings indicated significant benefit, two indicated significant detriment, and the remaining findings were non-significant.
Higher magnesium intake was linked to lower long-term changes in fasting glucose and insulin resistance.
An increase in the prevalence of cardiovascular disease is anticipated, with associated increases in health care costs, disability, and reduced quality of life.
The FDA is advising consumers not to purchase the following weight loss supplements due to hidden ingredients that may pose a significant cardiovascular risk to patients.
New data shows that patients receiving Qsymia (phentermine HCl/topiramate extended-release; Vivus, Inc.) capsules, in conjunction with lifestyle modifications, experienced significant weight loss along with markedly reduced progression to type 2 diabetes and improvements in multiple cardiometabolic disease risk factors.
There is still insufficient evidence to support probiotic use to manage colic or to prevent infant crying.
OxyElite Pro, a dietary supplement, may be linked to 24 cases of acute non-viral hepatitis reported in Hawaii.
Individuals with posttraumatic stress disorder (PTSD) are at increased risk for metabolic syndrome.
Delayed gluten introduction and increased length of breastfeeding are associated with increases in the risk of celiac disease (CD).
Adolescents are exposed to athlete-endorsed food and beverages, the majority of which are energy-dense and nutrient-poor.
The FDA has approved Clinolipid (lipid injectable emulsion; Baxter) for parenteral nutrition in adult patients who are unable to eat or drink.
The energy and sodium content of menu items at chain restaurants did not change significantly from 2010-2011 despite industry pledges to offer healthier foods.
Among chronic opioid users who undergo bariatric surgery, about three-quarters continue chronic opioid use after surgery, with an increase in opioid dose.
Vegetable protein and fat intakes, including peanut butter and nuts, during pre-adolescence may subsequently help reduce the risk for benign breast disease (BBD).
Vertex has submitted a supplemental New Drug Application (sNDA) to the FDA for the approval of Kalydeco (ivacaftor) monotherapy for people with cystic fibrosis (CF) ages 6 and older who have at least one non-G551D gating mutation in the CFTR gene.
While being overweight increases the risk of cardiovascular events in patients with type 2 diabetes, overweight is also associated with lower mortality in older patients.
Vitamin D supplementation alone does not improve bone health in postmenopausal women, but calcium alone or in combination with vitamin D does appear to reduce bone turnover.
Results from genetic testing for weight gain-related genes may offer psychological benefits beyond their limited clinical utility.
Despite significant weight loss, bariatric surgery does not necessarily lead to improved glycemic control in adolescents with type 1 diabetes mellitus.
Pharmagen has launched Clotamin, a new vitamin K-free multivitamin formulation, in retail CVS stores.
In obese patients, excess weight loss was associated with significant reductions in A1C and fasting blood glucose.
For overweight and obese adults with knee osteoarthritis, 18 months of diet and diet + exercise interventions is better than an exercise only intervention.
The American College of Physicians (ACP) has developed a clinical practice guideline for the management of obstructive sleep apnea (OSA) in adults.
Almost all new mothers experience breastfeeding concerns in the early postpartum period, and these are associated with stopping breastfeeding.
Parents of obese children should be targeted in an effort to deal with a serious national problem.
Maternal obesity is associated with considerable negative maternal and neonatal outcomes as well as substantially increased medical costs.
Phototherapy with ultraviolet (UV) A1 radiation induces a reduction in serum 25-hydroxyvitamin D3 (25[OH]D) levels, whereas narrowband UVB (UVBnb) and UVA/UVBnb induces significant increases in serum 25(OH)D.
Vitamin B supplements may help reduce the risk of stroke.
Routine screening can identify older adults at risk of mobility limitation, and addressing their functional deficits with mobility devices and exercise can lead to improvement in mobility limitation.
Barriers and enablers for good nutrition and physical activity influence employee health behaviors.