Study Sheds Light on Link Between Immunotherapy and Arthritis Onset

By June 24, 2016

A new study has shed light on an association between immune checkpoint inhibitors (ICIs) and the onset of inflammatory arthritis and sicca syndrome.

Hypertension, Pain Combo Drug Shown Beneficial on Kidney Function

By June 24, 2016

Kitov Pharmaceuticals announced new study data from the Phase 3 study for KIT-302 (amlodipine besylate/celecoxib) in the treatment of osteoarthritis pain and hypertension, suggesting beneficial effects on renal function.

Severely Lower Med Adherence in COPD Patients with Depression

By June 24, 2016

For patients with Chronic Obstructive Pulmonary Disease (COPD) and a co-morbidity of depression, adherence to COPD maintenance medication is particularly low.

Study Examines QoL/Mood Outcomes of Adjunct Seizure Therapy, Lacosamide

By June 24, 2016

A 28-week open-label study of the adjunct antiepileptic drug, lacosamide, showed that it had a low risk of adverse mood effects and a low risk for overall effect on cognition.

Flublok 9-Month Shelf Life Approved by FDA

By June 24, 2016

The Food and Drug Administration (FDA) has approved a longer shelf life for the influenza vaccine Flublok (Protein Sciences), extending the previous shelf life of 6 months to 9 months from the date of manufacture.

FDA Grants Napabucasin Orphan Drug Status for Gastric Cancer

By June 24, 2016

The Food and Drug Administration (FDA) has granted Orphan Drug designation for the investigational compound, napabucasin (Boston Biomedical), for the treatment of gastric cancer, including gastroesophageal junction (GEJ) cancer.

Wearable Device Could Monitor Opioid Use in Real Time

By June 24, 2016

A wearable biosensor has been shown to detect consistent physiological patterns after opioid administration, which could eventually provide a new method of opioid monitoring.

CDC - Nasal Flu Vaccine Ineffective, Should Not Be Used Next Season

June 24, 2016

The nasal spray form of the influenza vaccine should not be used next flu season, according to an announcement by the U.S. Centers for Disease Control and Prevention's Advisory Panel on Immunization Practices (ACIP).

Zika Symptoms May Be Harsher for Those Predisposed to Dengue

June 24, 2016

Prior exposure to the dengue fever virus may increase the severity of Zika virus infection, according to a study published online June 23 in Nature Immunology.

Gene Sequence Analysis Can ID Malaria Resistant Mutations

June 24, 2016

Plasmodium falciparum gene Kelch (K13)-propeller sequence polymorphism analysis can assist with surveillance of artemisinin resistance, according to a study published in the June 23 issue of the New England Journal of Medicine.

Sabril REMS Update Ends OAF Requirement

By June 23, 2016

The Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for Sabril (vigabatrin; Lundbeck) tablets, meaning prescribers will no longer be required to submit an ophthalmologic assessment form (OAFs) as part of the risk evaluation and mitigation strategy (REMS).

Blood Clots May be Directly Targeted With Magnetically Controlled Enzyme

By June 23, 2016

A new magnetically controlled drug may be able to dissolve a blood clot without negatively affecting the entire network of blood vessels.

Study Finds Significant HF Mortality Reductions with ARNI Therapy

By June 23, 2016

The sensitivity analysis showed a lower limit of 18,230 preventative deaths per year associated with ARNI.

Zika Patients Urged to Report Every Symptom After Uveitis Link Discovered

June 23, 2016

In a letter published online in the New England Journal of Medicine, researchers describe the case of a man who was infected with Zika and developed uveitis.

Age and Start of Treatment Are Key to Positive Outcomes in Cystic Fibrosis

June 23, 2016

For patients with cystic fibrosis (CF), early treatment of Pseudomonas aeruginosa (Pa) may be beneficial, according to a study published online June 16 in the Journal of Clinical Pharmacy and Therapeutics.

Jakafi Granted Breakthrough Therapy Status for Graft-Versus-Host Disease

By June 23, 2016

The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for Jakafi (ruxolitinib; Incyte) for the treatment of patients with acute graft-versus-host disease (GVHD).

Avycaz Labeling Updated with Clinical Data for cIAI

By June 23, 2016

The Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for Avycaz (ceftazidime/avibactam; Allergan) to update its labeling with clinical data in the treatment of complicated intra-abdominal infections (cIAI) caused by susceptible microorganisms.

Tablet Splitting Can Significantly Vary Doses, FDA Study Finds

By June 23, 2016

An FDA report found that certain split tablets did not meet USPs Uniformity of Dosage Units accepted criteria.

Spending on Alt Medicine Reaches New High in U.S.

June 23, 2016

Americans spent more than $30 billion out of pocket in 2012 on chiropractors and other complementary health practitioners, as well as supplements and other forms of alternative medicine, according to research published online in the U.S. Centers for Disease Control and Prevention's National Health Statistics Reports.

Regular Exercise in Children With T1DM May Lower Atherosclerosis Risk

June 23, 2016

For children with type 1 diabetes, the number of daily steps is associated with early signs of atherosclerosis and adverse cardiovascular risk, according to a study published in Diabetes Care.

Does Prior TNFi Use Affect Secukinumab Effectiveness in Psoriatic Arthritis?

By June 22, 2016

Secukinumab, a human anti-IL-17A monoclonal antibody, was shown to be effective in both tumor necrosis factor inhibitor (TNFi)-naïve and TNFi-exposed psoriatic arthritis patients, however greater improvements were noted in TNFi- naïve patients.

Investigational Drug for Huntington's Disease Granted Orphan Drug Status

By June 22, 2016

The Food and Drug Administration (FDA) has granted Orphan Drug designation to the investigational drug WVE-120101 (Wave Life Sciences) for the treatment of Huntington's disease (HD).

Acne Outcomes Vary Based on Hormonal Contraceptive Used

By June 22, 2016

A patient-reported study of hormonal contraceptives has found a significantly varied effect on acne among commonly prescribed agents.

Real-World Study Compares Treatment Persistence, Discontinuation of Oral Anticoagulants in Afib Patients

By June 22, 2016

Rivaroxaban, a non-vitamin K antagonist (VKA) oral anticoagulant, was found to have better persistence and lower discontinuation rates than, the VKA warfarin and the non-VKA, dabigatran.

Vitamin D Levels Tied to Survival in Pancreatic Cancer

June 22, 2016

Longer overall survival for patients with sufficient prediagnostic 25-hydroxyvitamin D

Despite Guidelines, Many At-Risk Afib Patients Not Getting Anticoagulants

June 22, 2016

Anticoagulants -- not aspirin -- dramatically cut the risk of stroke, researchers say

Screening Recommendations for Childhood Lead Exposure

June 22, 2016

American Academy of Pediatrics calls for stronger regulations and new laws to protect children

Lack of Exercise May Increase Epithelial Ovarian CA Risk

June 22, 2016

Lack of exercise is associated with an increased risk of epithelial ovarian cancer (EOC) and mortality, two new studies suggest.

Women at Higher Risk of Progressive High Myopia Than Men

June 22, 2016

About 9.6 million Americans are severely myopic, according to a study published online June 21 in Ophthalmology.

Efficacy of Buprenorphine Patches in Diabetic Peripheral Neuropathic Pain

By June 21, 2016

Transdermal buprenorphine may be an effective therapy for diabetic peripheral neuropathic pain (DPNP), however it was associated with a high rate of adverse events, mostly nausea and/or vomiting.

Evaluating Optimal Therapy for Complicated Grief

By June 21, 2016

Data from the first randomized clinical trial evaluating the efficacy of antidepressants with or without complicated grief psychotherapy for the treatment of complicated grief showed that adding citalopram to complicated grief treatment (CGT) helped treat concurrent depressive symptoms.

Aspirin for Primary Prevention: A Delicate Balancing Act

By June 21, 2016

These two cases illustrate the difficulty of weighing the potential benefits and risks of aspirin use for primary prevention of ASCVD.

Comparing Treatment Interventions in Obsessive-Compulsive Disorder

By June 21, 2016

Combining psychotherapeutic and psychopharmacological interventions is likely to be more efficacious than psychotherapeutic interventions alone for the management of obsessive-compulsive disorder (OCD), a study published in Lancet Psychiatry has shown.

LDL Targets May Need Reevaluation for Some CVD Patients, Study Finds

June 21, 2016

Very low target low-density lipoprotein (LDL) cholesterol levels may not benefit all patients with preexisting heart disease, according to a study published online June 20 in JAMA Internal Medicine.

Efficacy of Long-Term Pioglitazone Assessed in Patients with NASH, T2DM

June 21, 2016

Safe and effective for patients with prediabetes or type 2 diabetes and nonalcoholic steatohepatitis

Can a 'Reset Room' Help with Physician Burnout?

June 21, 2016

Reset room is one of three steps Hennepin County Medical Center has introduced to address burnout

Rayaldee Approved for Secondary Hyperparathyroidism in Adults with CKD

By June 21, 2016

Opko Health announced that the Food and Drug Administration (FDA) has approved Rayaldee (calcifediol) extended-release capsules for the treatment of secondary hyperparathyroidism (SHPT) in adults with Stage 3 or 4 chronic kidney disease (CKD) and serum total 25-hydroxyvitamin D <30ng/mL.

NDA for Potential ALS Treatment Submitted to FDA

By June 21, 2016

Mitsubishi Tanabe Pharma announced that a New Drug Application has been submitted to the Food and Drug Administration (FDA) for edaravone (MCI-186) for the treatment of amyotrophic lateral sclerosis (ALS).

Do Statins Improve Outcomes in COPD Patients?

By June 21, 2016

Statin use was not associated with a lower risk of all-cause mortality or time until first hospitalization for an acute exacerbation of chronic obstructive pulmonary disease (COPD), a study published in BMJ Open Respiratory Research has found.

How Effective Is Acetaminophen in Tension-Type Headaches?

By June 21, 2016

Acetaminophen 1000mg demonstrated a small benefit in regards to being pain-free at 2 hours for patients with frequent tension-type headache (TTH) who have an acute headache of moderate or severe intensity, study authors reported in a Cochrane review.

Contaminated Gloves May Be Spreading Bacteria in Hospitals

By June 20, 2016

Bacteria on healthcare workers' gloves can contaminate hospital surfaces and lead to the spread of healthcare associated infections (HCAIs), a new research paper has found.

Morphine to Hydrocodone: Switching Between Two Extended-Release Pain Drugs

By June 20, 2016

According to a study published in Pain Practice, patients with moderate-to-severe chronic pain who switch from morphine extended-release (ER) to once-daily hydrocodone bitartrate experienced maintained or improved pain relief without an increase in safety concerns.

HCV and Psychoactive Treatments: Managing Drug Interactions

By June 20, 2016

A review published in Clinical Pharmacokinetics describes evidence-based interactions between direct-acting antivirals and psychoactive drugs and provides safe strategies for concomitant treatment of psychiatric illnesses and chronic hepatitis C virus (HCV) infection.

AAMC: How to Alleviate the Impending Physician Shortage

June 20, 2016

Steps should be taken to combat the impending physician shortage of between 61,700 and 94,700 doctors that the U.S. is expected to face over the next decade.

Can Sacubitril/Valsartan and Simvastatin Be Taken Concomitantly?

By June 20, 2016

Data from an open-label, fixed-sequence study showed that although sacubitril inhibited organic anion-transporting polypeptides (OATP)1B1 and OATP1B3 in vitro, this did not translate to any clinically relevant in vivo effect.

Afstyla Now Available for Hemophilia A Patients

By June 20, 2016

CSL Behring announced that Afstyla (antihemophilic factor VIII [recombinant], single chain) is now available for children and adults with hemophilia A.

IV Lidocaine, Amitriptyline Combo Evaluated in Fibromyalgia

June 20, 2016

No clinical manifestations for combination of lidocaine for four weeks with amitriptyline

Fighting Zika: Potential Drug Target Discovered

June 20, 2016

Gene pathway that allows virus to move from one cell to the next could be future drug target

Multi-Interventional Approach Reduces Pediatric Hypoglycemic Events

June 20, 2016

Approach can reduce preventable hypoglycemic events in hospitalized children receiving insulin

Benefits of Vitamin D: How Much Evidence is Really Out There?

By June 17, 2016

Examining vitamin D from a scientific standpoint finds that many supposed benefits are not validated.

Can Statin Use Lower the Risk of Post-Stroke Infections?

By June 17, 2016

For patients with ischemic stroke without endotracheal intubation, use of statins were associated with a reduced risk of nosocomial infections, study authors from Washington State University reported.

Metformin Add-On Treatments Show Varying Degrees of Safety

June 17, 2016

For patients with type 2 diabetes who are taking metformin, the risk of cardiovascular events and mortality varies with the addition of different second-line therapies, according to a study published online in Diabetes, Obesity and Metabolism.

Adolescents May Have Lower Trough Target With Vancomycin Tx

June 17, 2016

The target trough concentration of vancomycin seems to be lower for adolescents than for adults, according to a study published online in the Journal of Clinical Pharmacology.

Recombinant tPA May Be Safe For Wake-Up Stroke Patients

June 17, 2016

For patients with wake-up stroke (WUS), treatment with recombinant tissue plasminogen activator (rtPA) seems safe, according to a study published online in the Annals of Neurology.

Improved HDL-C Levels Tied to Gluten-Free Diet in Children With T1D

June 17, 2016

For children with type 1 diabetes (T1D), the negative influence of celiac disease (CD) on high-density lipoprotein cholesterol (HDL-C) can be improved by adherence to a gluten-free diet (GFD), according to a study published online June 6 in Diabetes Care.

Smoking Status, Age May Impact Efficacy of Breast Cancer Meds

By June 17, 2016

According to a study published in the British Journal of Cancer, a common medication for breast cancer may have reduced efficacy in patients who smoke vs. non-smokers.

Neurocognitive and Work Functioning Improved With Desvenlafaxine

By June 17, 2016

A study published in the Journal of Affective Disorders concluded that there were no significant associations between changes in neurocognitive and work functioning measures in employed patients with major depressive disorder (MDD).

Initial NDA for Investigational ALK Inhibitor Submitted to FDA

By June 17, 2016

Ariad Pharmaceuticals announced the initiation of the first part of a rolling New Drug Application (NDA) submission to the Food and Drug Administration (FDA) for its investigational agent, brigatinib, for the treatment of patients with anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who are resistant to crizotinib.

Higher Allopurinol Dose May be Nephroprotective in Elderly

By June 17, 2016

A higher allopurinol dose provided a protective effect against incident renal failure in elderly patients, according to a study published in Annals of the Rheumatic Diseases.

Intervention Pharmacist Care May Improve CVD Outcomes

June 17, 2016

Patients with poorly controlled cardiovascular disease (CVD) risk factors could improve their prognosis by having pharmacists help manage their care, according to a study published in the Journal of the American College of Cardiology.

Zika Infection in 3rd Trimester May Not Harm Development

June 17, 2016

Colombian study found no cases of microcephaly when infection occurred in 3rd trimester

Mechanical Stress May Cause Melanoma on the Soles of Feet

June 17, 2016

Stress and damage caused by walking or running could be a risk factor for melanoma on the soles of the feet, according to a research letter published in the June 16 issue of the New England Journal of Medicine.

Review of Pediatric Type 2 Diabetes Treatments

By June 16, 2016

For pediatric patients with type 2 diabetes, metformin and insulin continue to be the mainstay of treatment, study authors concluded in a review published in Annals of Pharmacotherapy.

USPSTF Updates Recommendations For Colorectal Screening

By June 16, 2016

The guidance recommends screening for all 50 to 75 year-olds but USPSTF say more studies are needed to advise on specific screening options.

Tocilizumab vs. Methotrexate Compared in Newly Diagnosed RA Patients

By June 16, 2016

Immediate initiation with tocilizumab with or without methotrexate was more effective than methotrexate alone for patients with newly diagnosed rheumatoid arthritis, researchers concluded in a study published in The Lancet.

Statins May Offer Protective Effect Against New-Onset IBD

By June 16, 2016

Statins may offer a protective effect against new-onset irritable bowel disease (IBD), Crohn's disease (CD), and ulcerative colitis (UC), according to a study published in The American Journal of Gastroenterology.

Sustained Opioid Abstinence Seen with Buprenorphine Implant

By June 16, 2016

Braeburn Pharmaceuticals presented data from the Phase 3 study of Probuphine for the long-term maintenance treatment of opioid dependence at the 78th Annual Scientific Meeting of The College on Problems of Drug Dependence (CPDD).

PreserVision AREDS Formula + Multivitamin Launched for AMD Patients

June 16, 2016

Valeant announced that PreserVision AREDS 2 Formula + Multivitamin is now available for patients with moderate to advanced age-related macular degeneration.

Vedolizumab Compared to Certolizumab Pegol for Crohn's Disease Treatment

By June 16, 2016

No statistically significant differences in efficacy and safety were seen between vedolizumab and certolizumab pegol for the treatment of Crohn's disease, a study published in Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy has found.

Longer Euglycemic Period With Bydureon Seen in Phase 4 Study

By June 16, 2016

AstraZeneca announced data from a 10-week Phase 4 randomized, controlled, double-blind study assessing the quality of glucose control with Bydureon (exenatide extended-release) for injectable suspension vs. placebo using continuous glucose monitoring in patients with type 2 diabetes uncontrolled on metformin.

Tenofovir Disoproxil Fumarate Use During Pregnancy May Cut HBV Transmission

June 16, 2016

Use of TDF in pregnancy is associated with a reduced rate of mother-to-child transmission

Breastfed Preemies May Have Healthier Hearts Later in Life

June 16, 2016

Breastfeeding premature infants appears to increase the likelihood that those infants will have healthier hearts in young adulthood, according to research published online in Pediatrics.

Researchers Advocate a Standard of Care For HIV-Related Lymphomas

June 16, 2016

Patients living with HIV are at high risk for lymphoma, and, according to a study published online June 13 in Blood, autologous hematopoietic stem-cell transplantation (aHSCT) should be standard treatment in these cases.

Does Ease of Access to Alcohol Affect Risk of Heart Conditions?

June 16, 2016

Texans living in "dry" counties are more likely to suffer myocardial infarction and congestive heart failure than those living in nearby "wet" counties, where alcohol sales are legal; however, atrial fibrillation is less likely in dry counties, according to a study published online in the BMJ.

Melanoma Risk with PDE5 Inhibitors Likely Due to Sun, Not Side Effect

June 16, 2016

The small apparent increase in risk of melanoma in men prescribed phosphodiesterase type 5 (PDE5) inhibitors may be explained by greater sun exposure, according to new research published online in PLOS Medicine.

Real-World Data Shows Effective Switch to Toujeo in Diabetes Patients

By June 15, 2016

Sanofi announced new real-world data on Toujeo (insulin glargine injection) regarding change in HbA1c and occurrence of hypoglycemia in patients up to 6 months after switching to Toujeo from another basal insulin.

More Education on HIV PrEP Needed, AMA Urges

By June 15, 2016

The American Medical Association (AMA) announced new policies addressing the need for better education of physicians on the effective use of pre-exposure prophylaxis (PrEP) to prevent HIV acquisition in high-risk individuals.

Company Halts Clinical Program for Ganaxolone in Adult Seizures

By June 15, 2016

Marinus Pharmaceuticals announced top-line results from the Phase 3 clinical trial of ganaxolone in adults with drug-resistant focal onset seizures.

WHO Changes Stance on Carcinogenicity of Coffee

By June 15, 2016

No conclusive evidence was found to suggest that drinking coffee has carcinogenic effect on humans, however a pooled data analysis showed that drinking 'very hot' beverages may increase the relative risk for esophageal cancer.

Studies Tie Canagliflozin Use to A1C Reductions, Improved Adherence in T2D Patients

By June 15, 2016

Invokana (canagliflozin) use was found to be superior when compared with dipeptidyl peptidase-4 (DPP-4) inhibitors for reducing A1C, increasing treatment adherence, and was shown to improve results when used as an add-on therapy to metformin and sitagliptin.

Tradjenta Use Safe, Effective in T2DM Patients at Risk for Renal Impairment

By June 15, 2016

Tradjenta (linagliptin; Boehringer Ingelheim and Lilly) reduced blood sugar in adults with type 2 diabetes at risk for renal impairment, with a renal safety profile similar to that seen in other trials, according to findings from the MARLINA-T2D study.

Follow-on Biologic Insulin Glargine Candidate Similar to Lantus in Two Studies

June 15, 2016

Merck announced that two Phase 3 studies evaluating MK-1293, an investigational, follow-on biologic insulin glargine candidate for the treatment of patients with type 1 and type 2 diabetes, achieved their primary endpoints. Study data was presented for the first time at the 76th Scientific Sessions of the American Diabetes Association.

FDA Rejects Approval of Pain Drug Apadaz

By June 15, 2016

KemPharm announced that the Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) for the New Drug Application (NDA) of Apadaz (benzhydrocodone and acetaminophen) for the treatment of moderate to moderately severe acute pain.

Glassia Now Approved for Self-Infusion at Home

By June 15, 2016

Shire and Kamada announced that the Food and Drug Administration (FDA) has approved Glassia (alpha-1 proteinase inhibitor [human]) as the first treatment for adults with emphysema due to severe alpha-1 antitrypsin (AAT) deficiency that can be self-infused at home after appropriate training.

Mortality Risk Compared in Pain Patients Prescribed Long-Acting Opioids vs. Alternative Medications

June 15, 2016

Much of the risk related to cardiovascular complications, not overdoses

Fycompa Oral Suspension Launched for Patients with Swallowing Difficulty

By June 15, 2016

Eisai announced the availability of Fycompa (perampanel) Oral Suspension for use in patients who have difficulty swallowing tablets or prefer liquids.

Higher Dosage Strength for HT-1 Treatment Approved

By June 15, 2016

Sobi announced that the FDA has approved a new 20mg strength of Orfadin (nitisinone) capsules for the treatment of hereditary tyrosinemia type-1 (HT-1), a rare genetic disease in infants and children.

AMA Discourages Use of "Smart Drugs"

By June 15, 2016

The American Medical Association (AMA) announced the adoption of a new policy discouraging the nonmedical use of prescription drugs for cognitive enhancement in healthy individuals.

How Effective Are Prescription Weight-Loss Drugs?

June 15, 2016

Any of the prescription weight-loss drugs on the market can help obese adults lose weight, although some appear to be more effective than others.

Should Asymptomatic Patients Be Screened for OSA?

June 15, 2016

The U.S. Preventive Services Task Force (USPSTF) has found insufficient evidence for the benefit of obstructive sleep apnea (OSA) screening in asymptomatic populations.

FDA Strengthens Renal Injury Warnings for Some Diabetes Meds

By June 14, 2016

The Food and Drug Administration (FDA) announced it is strengthening the current warning about the risk of acute kidney injury for drug products containing canagliflozin (Invokana, Invokamet) and dapagliflozin (Farxiga, Xigduo XR).

Rates of Hypoglycemia Compared with Tresiba, Insulin Glargine

By June 14, 2016

Treatment with Tresiba (insulin degludec injection) resulted in significantly lower rates of overall, nocturnal, and severe hypoglycemia vs. insulin glargine U-100, according to new data from two Phase 3b SWITCH trials.

Ertugliflozin Monotherapy, Combo Tx Evaluated in T2DM Studies

By June 14, 2016

Merck and Pfizer announced that VERTIS Mono and VERTIS Factorial, two Phase 3 studies evaluating the investigational oral SGLT-2 inhibitor, ertugliflozin, for the treatment of patients with type 2 diabetes, met their primary endpoints. Study results were presented for the first time at the 76th Scientific Sessions of the American Diabetes Association.

Unique Obesity Treatment Device Gets FDA Approval

By June 14, 2016

The device - which is inserted through a small incision in the abdomen - was associated with a ~12.1% total body weight loss in a clinical trial.

Liraglutide Shown to Improve CV Outcomes for T2DM Patients

By June 14, 2016

Data from the LEADER trial showed liraglutide was able to safely and effectively lower the overall risk of heart attack, stroke, or cardiovascular death among patients with type 2 diabetes at high risk for cardiovascular disease.

FDA to Review Deflazacort for Duchenne Muscular Dystrophy

By June 14, 2016

Marathon Pharmaceuticals announced the submission of a New Drug Application (NDA) to the Food and Drug Administration (FDA) for deflazacort for the treatment of patients with Duchenne Muscular Dystrophy (DMD).

GoNitro Sublingual Powder Approved for Angina

By June 14, 2016

Espero announced that the Food and Drug Administration (FDA) has approved GoNitro (nitroglycerin) sublingual powder for acute relief of an attack or prophylaxis of angina pectoris due to coronary artery disease.

Sleep-Deprived? Caffeine May Help, But Only for a Short Time

By June 14, 2016

Caffeine can help improve alertness and performance in those with restricted sleep patterns individuals but the effects wane after the second consecutive day with just 5 hours of time in bed (TIB).

Evaluating Anaphylaxis Risk in Siblings of Peanut Allergic Children

June 14, 2016

Parents are anxious about introducing peanuts at home without prior skin testing

Treating Herpes Simplex Viral Keratitis: What Are the Options?

June 14, 2016

Options include acyclovir, valacyclovir, topical ganciclovir; need for development of new compounds