Dry Eyes: Updates on Risk Factors, Diagnosis, Tx

Dry Eyes: Updates on Risk Factors, Diagnosis, Tx

As dry eyes is one of the most common reasons for patient visits to eye care professionals, the latest issue of the journal Optometry and Vision Science focuses on progress in the risk factors, diagnosis, and treatment of dry eye disease.

Aptiom Gains Monotherapy Indication for Seizure Tx

Aptiom Gains Monotherapy Indication for Seizure Tx

Sunovion announced that the Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) for Aptiom (eslicarbazepine acetate) as monotherapy for the treatment of partial-onset seizures.

Purple Potatoes May Suppress Colon Cancer Stem Cells

Purple Potatoes May Suppress Colon Cancer Stem Cells

Purple potatoes may contain compounds that help destroy colon cancer stem cells and limit metastasis, according to a new study published in the Journal of Nutritional Biochemistry.

Probiotics in the ICU: Can They Prevent, Fight Superbugs?

Probiotics in the ICU: Can They Prevent, Fight Superbugs?

Probiotics did not help prevent or eliminate gastrointestinal colonization with drug-resistant organisms in patients in the intensive care unit (ICU) vs. standard care, researchers presented.

Potential Drug Therapy ID'ed to Boost Resilience to Tinnitus

Potential Drug Therapy ID'ed to Boost Resilience to Tinnitus

Researchers have discovered the molecular mechanisms responsible for the development of noise-induced tinnitus and possible drug therapy that may reduce the susceptibility to this condition based on their findings.

FDA Approves Second PCSK9 Inhibitor for High Cholesterol

FDA Approves Second PCSK9 Inhibitor for High Cholesterol

The Food and Drug Administration (FDA) has approved Repatha (evolocumab; Amgen) for the treatment of high cholesterol in certain adults.

New Insight into Antibiotics-Type 2 Diabetes Link

New Insight into Antibiotics-Type 2 Diabetes Link

Researchers have found patients with type 2 diabetes used more antibiotics in the years prior to diagnosis compared to healthy individuals according to a new study published in the Journal of Clinical Endocrinology & Metabolism.

Letairis/Tadalafil Combo Demonstrates Efficacy for Pulmonary HTN

Gilead Sciences announced positive results from the AMBITION study, a Phase 3/4 trial of first-line combination therapy with Letairis (ambrisentan) and tadalafil in patients with WHO/NYHA functional class II and III pulmonary arterial hypertension (PAH).

Novel Antibiotic Fast Tracked for Bacterial Vaginosis

The Food and Drug Administration (FDA) has granted SYM-1219 (secnidazole, Symbiomix) Fast Track designation for the treatment of bacterial vaginosis (BV).

Edurant Label Updated With New Pediatric Indication, Warning

Edurant Label Updated With New Pediatric Indication, Warning

The Food and Drug Administration announced that the Edurant (rilpivirine; Janssen) labeling has been updated to include a new pediatric indication and changes in the Warnings and Precautions and Adverse Reactions sections.

How "Stepped Care" Could Help Uncontrolled Hypertension

How "Stepped Care" Could Help Uncontrolled Hypertension

A novel "stepped care" treatment approach was effective in improving blood pressure control among patients with severe intolerance to antihypertensives, a study published in the Journal of Clinical Hypertension reported.

Synjardy Tabs Approved for Type 2 Diabetes

Synjardy Tabs Approved for Type 2 Diabetes

Boehringer Ingelheim and Eli Lilly announced that the Food and Drug Administration (FDA) has approved Synjardy (empagliflozin, metformin HCl) as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes who are not adequately controlled on a regimen containing empagliflozin or metformin, or in patients already being treated with both empagliflozin and metformin.

FDA Finds Undeclared Salicylic Acid in Weight Loss Caps

Novacare announced a voluntary recall of dietary supplements marketed as an aid to weight loss due to undeclared salicylic acid.

Sexual Side Effects of BPH Drugs May Last in Tx

Sexual Side Effects of BPH Drugs May Last in Tx

A review in the journal Endocrine Reviews and Metabolic Disorders reports that greater education and awareness of the potential risks associated with two treatments for benign prostate hyperplasia (BPH) is needed among both patients and clinicians, along with additional research exploring these reported adverse effects.

FDA Accepts Eteplirsen NDA for Duchenne Muscular Dystrophy

The Food and Drug Administration (FDA) has accepted the New Drug Application (NDA) for eteplirsen (Sarepta) for the treatment of Duchenne muscular dystrophy (DMD) amenable to exon 51 skipping.

TENS Device Highly Effective for Migraine Relief in Study

TENS Device Highly Effective for Migraine Relief in Study

Cefaly transcutaneous electrical nerve stimulation (TENS) device provided relief to 81 percent of migraine sufferers who used it, according to results of a clinical study published in The Journal of Headache and Pain.

New e-pill Auto Dispensing System to Improve Med Adherence

New e-pill Auto Dispensing System to Improve Med Adherence

e-pill announced the launch of the e-pill MedTime PLUS Medication Reminder and Dispensing System with new features to improve patient compliance and medication adherence.

Novel Drug Granted Orphan Designation for Rare Musculoskeletal Disorder

The Food and Drug Administration (FDA) has granted AT001 (Audentes) Orphan Drug designation for the treatment of X-Linked Myotubular Myopathy (XLMTM).

RiduZone Dietary Supplement Gets FDA Clearance

RiduZone Dietary Supplement Gets FDA Clearance

NutriForward announced that the Food and Drug Administration (FDA) has cleared their patented product RiduZone tablets as a dietary supplement for regulation and support of healthy weight, appetite, body-fat composition, and cholesterol levels in adults.

Cambrooke Launches Medical Food Line for Inborn Errors of Metabolism

Cambrooke Launches Medical Food Line for Inborn Errors of Metabolism

Cambrooke Therapeutics announced the availability of a family of amino-acid based medical foods for the dietary management of several disorders of amino acid metabolism.

New Transdermal Delivery System for Migraine Tx Launched

New Transdermal Delivery System for Migraine Tx Launched

Teva CNS announced the launch of Zecuity (sumatriptan iontophoretic transdermal system) indicated for the treatment of migraine with or without aura in adults.

OTC Laser Tx for Male Baldness to Be Evaluated in Study

OTC Laser Tx for Male Baldness to Be Evaluated in Study

Theradome announced that it has initiated one of the most comprehensive studies to date to evaluate its Theradome LH80 PRO Laser Helmet on men with thinning hair or who are showing signs of balding.

Too Much of This Mineral May Lead to Increased Appetite, Overeating

Too Much of This Mineral May Lead to Increased Appetite, Overeating

Can too much red meat consumption lead to an increased appetite and overeating? Yes, according to a study published in the Journal of Clinical Investigation which found that dietary iron intake can suppress the hormone leptin that is linked to appetite regulation.

Burning Incense May Be a Health Hazard

Burning Incense May Be a Health Hazard

Use of incense indoors may have detrimental health consequences according to a new study published in the journal Environmental Chemistry Letters.

Fully Mobile Continuous Glucose Monitoring System Approved

Fully Mobile Continuous Glucose Monitoring System Approved

The Food and Drug Administration (FDA) has approved the Dexcom G5 Mobile Continuous Glucose Monitoring (CGM) System, the first fully mobile real-time diabetes management device for adults and children aged 2 years and older.

Can Exercise Improve Cognitive Function?

Can Exercise Improve Cognitive Function?

A new study published in the Journal of the American Medical Association (JAMA) examines the effect of physical activity on cognitive function.

What a New Study Says About Omega-3s and Brain Health

What a New Study Says About Omega-3s and Brain Health

In one of the largest and longest studies of its kind, researchers examined whether supplementation with omega-3 fatty acids helped to slow cognitive decline in older patients.

Positive Results for First Long-Acting Injection-Free GLP-1 Agonist

Intarcia Therapeutics has announced that the Phase 3 trial of ITCA 650 (exenatide) demonstrated positive top-line results in reducing HbA1c in patients with type 2 diabetes following a year of treatment.

Anti-PDL1 Immunotherapy Demonstrates Efficacy in Phase 2 NSCLC Study

Genentech announced that the Phase 2 study of atezolizumab met its primary endpoint and shrank tumors in people with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose disease expressed PD-L1 (Programmed Death Ligand-1).

BromSite NDA Accepted for Post-Cataract Surgery

The Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for BromSite (0.075% bromfenac; InSite Vision) for the treatment of inflammation and prevention of ocular pain post-cataract surgery.

FDA Accepts Keytruda sBLA for First-Line Melanoma Indication

The Food and Drug Administration (FDA) has accepted for review the sBLA for Keytruda (pembrolizumab, Merck) for the first-line treatment of unresectable or metastatic melanoma patients.

New Microbiome Therapy Granted Orphan Drug Designation for Recurrent CDI

New Microbiome Therapy Granted Orphan Drug Designation for Recurrent CDI

The Food and Drug Administration (FDA) has granted Orphan Drug designation to SER-109 (Seres Therapeutics) for the prevention of recurrent Clostridium difficile infection (CDI) in adults.

Adjunctive Fycompa Demonstrates Efficacy in PGTC Seizures

The Phase 3 trial for Fycompa (perampanel, Eisai) demonstrated statistically significant results when used as adjunctive therapy in the treatment of primary generalized tonic-clonic (PGTC) seizures in patients 12 years and older.

New Insight Into How Antidepressants Target Brain in Neuropathic Pain

New Insight Into How Antidepressants Target Brain in Neuropathic Pain

Commonly used antidepressants appear to target specific neurotransmitters in the brain that regulate chronic pain and depression-like symptoms, a newly understood mechanism that could shape future treatments for nerve pain and depression.

Positive Phase 3 Results for Meningococcal Group B Vaccine

Positive Phase 3 Results for Meningococcal Group B Vaccine

Pfizer announced positive topline results for Trumenba (meningococcal group B vaccine) in two Phase 3 trials.

Cabozantinib Receives Breakthrough Therapy Designation for Renal Cancer

The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to cabozantinib (Exelixis) for the treatment of patients with advanced renal cell carcinoma (RCC) who have received one prior therapy.

Pharmacists Helping to Prevent Opioid Overdoses With State Programs

Pharmacists Helping to Prevent Opioid Overdoses With State Programs

Pilot programs of pharmacy-based naloxone (PBN) education and distribution to patients in two states could serve as models for other states to help reach patients at risk for opioid overdose and their families, according to an article appearing in Harm Reduction Journal.

Discontinuing Antihypertensive Tx May Not Help Elderly With Cognition

Discontinuing Antihypertensive Tx May Not Help Elderly With Cognition

New research in JAMA Internal Medicine found that discontinuation of antihypertensive therapy in patients aged 75 and older with mild cognitive impairment did not lead to improvements in short-term cognitive, psychological, or general daily functioning.

Promacta Now OK For Patients Over 1 Year Old

Novartis announced that the Food and Drug Administration (FDA) has approved the extended use of Promacta (eltrombopag) for the treatment of thrombocytopenia in children over 1 year of age with chronic immune thrombocytopenia (ITP) who have not achieved an adequate response to corticosteroids, immunoglobulins, or splenectomy.

Despite Recs, Statin Use in the Very Elderly Continues to Climb

Despite Recs, Statin Use in the Very Elderly Continues to Climb

Use of statins for primary prevention in patients older than 79 years of age without vascular disease increased from 1999 to 2012 despite little evidence supporting their use in this patient population, according to a new study in JAMA Internal Medicine.

Particulate Matter Leads to Recall of Some Allergan Ophthalmic Products

Allergan plc. announced a voluntary recall of specific lots of REFRESH Lacri-Lube, REFRESH PM, FML (fluorometholone ophthalmic ointment) 0.1%, and Blephamide (sulfacetamide sodium and prednisolone acetate ophthalmic ointment USP) 10%/0.2% due to the presence of particular matter.

Why Patients With HIV May Need Additional MMR Immunization

Why Patients With HIV May Need Additional MMR Immunization

Even with vaccination, children with HIV may not have sufficient immunity against measles, mumps, and rubella, reports a new study in the journal Clinical Infectious Diseases.

FDA: Reports of Severe Allergic Reactions with Picato

FDA: Reports of Severe Allergic Reactions with Picato

The Food and Drug Administration (FDA) is warning about reports of severe allergic reactions and herpes zoster associated with the use of Picato (ingenol mebutate topical gel).

Insomnia Tx Could Help Combat Sleep Issues in TBI

Insomnia Tx Could Help Combat Sleep Issues in TBI

Ramelteon may be effective for the treatment of sleep disturbances after a traumatic brain injury (TBI), according to a new study published in the journal Archives of Physical Medicine and Rehabilitation.

Could Modafinil be the First "Smart Drug"?

Could Modafinil be the First "Smart Drug"?

Modafinil has been validated to be a "smart drug" that significantly promotes cognitive enhancement according to a new systematic review published in the journal European Neuropsychopharmacology.

Patients Expect Empathy from Clinicians Despite "Empty Vessel" View

Patients Expect Empathy from Clinicians Despite "Empty Vessel" View

A new study has found that the greater the patients' need for medical care, the more likely patients will see their physicians as "empty vessel," lacking any emotion or personal lives of their own.

Tdap Vaccination Rates Triple With New Automated Alerts

Tdap Vaccination Rates Triple With New Automated Alerts

New automated electronic alerts boosted Tdap vaccination rates in clinics, according to a new study from the University of Michigan Health System published in the American Journal of Public Health.

Positive Results for Jardiance in CV Risk Reduction Study

Positive Results for Jardiance in CV Risk Reduction Study

Boehringer Ingelheim and Lilly announced positive results from the EMPA-REG OUTCOME trial that evaluated cardiovascular (CV) outcomes for Jardiance (empagliflozin) in adults with type 2 diabetes at high risk for CV events.

What Tests, Txs May Be Unnecessary in Dermatology?

What Tests, Txs May Be Unnecessary in Dermatology?

The American Academy of Dermatology has issued new recommendations regarding potentially unnecessary dermatologic tests and treatments as part of the Choosing Wisely campaign.

Non-Adherence to Asthma Tx a Growing Problem

Non-Adherence to Asthma Tx a Growing Problem

An analysis published in the Journal of Clinical Pharmacy and Therapeutics of asthma medication adherence showed poor coverage across a six-month period.

When Should Pregnant Patients Worry About Headaches?

When Should Pregnant Patients Worry About Headaches?

Based on a new study published in Neurology, researchers have developed the first clinical recommendations for making diagnostic decisions regarding headaches in pregnant women.

Working Overtime? It Could Up Your Risk of Stroke

Working Overtime? It Could Up Your Risk of Stroke

An increased risk of stroke and coronary heart disease was associated with employees working 55 hours or more per week, according to a study published in the journal The Lancet.

Tomatoes as Gout Trigger? New Study Adds to Evidence

Tomatoes as Gout Trigger? New Study Adds to Evidence

Patients with gout often self-report foods like tomatoes and tomato products as dietary triggers, but consumption of these foods as a trigger of gout flares may not be supported by empirical evidence. A study in BMC Musculoskeletal Disorders reports on a positive association between tomato consumption and serum urate levels, but suggests that there may be a biological basis.

FDA Approves Addyi for Women with Hypoactive Sexual Desire Disorder

FDA Approves Addyi for Women with Hypoactive Sexual Desire Disorder

The Food and Drug Administration (FDA) has approved Addyi (flibanserin) for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to a co-existing medical or psychiatric condition, problems within the relationship, or the effects of a medication or other drug substance.

Is Poor Sleep a Major Factor in MS-Related Fatigue?

Is Poor Sleep a Major Factor in MS-Related Fatigue?

A new study published in the journal Frontiers in Neurology found that sleep disturbances may play a major role in secondary fatigue in multiple sclerosis (MS).

First Study on Transgender Youth Tx Outcomes Starting Soon

The first study in the United States to investigate the long-term outcomes of medical treatment for transgender youth is set to begin in the near future after having been awarded $5.7 million by the National Institutes of Health (NIH).

Cracked Child-Resistant Bottle Caps Prompt Oncology Drug Recall

Cracked Child-Resistant Bottle Caps Prompt Oncology Drug Recall

Merck announced a voluntary recall of Temodar (temozolomide) and its generic Temozolomide (Sandoz) capsules due to the potential for the bottle caps to be cracked.

Fewer Falls Seen in Homebound Elderly With Vit D Supplement

Fewer Falls Seen in Homebound Elderly With Vit D Supplement

Vitamin D supplementation for the elderly who are homebound may help reduce the number of falls, according to new research.

New Humalog KwikPen Strength Launched for Diabetes

New Humalog KwikPen Strength Launched for Diabetes

Eli Lilly and Company announced the launch of Humalog 200 units/mL KwikPen (insulin lispro 200 units/mL [U-200]).

Brain Network Linked to Cognitive Changes in MS ID'ed in First-of-Kind Study

Brain Network Linked to Cognitive Changes in MS ID'ed in First-of-Kind Study

A first-of-its-kind study in Neuropsychology has found that decreased connectivity between network-specific brain regions is linked to the central deficit common to the various cognitive changes associated with multiple sclerosis (MS), slowed cognitive speed.

Tinzaparin vs. Warfarin: Which is Safer for VTE in Cancer Patients?

According to a new study published in JAMA, treatment with low molecular-weight heparin tinzaparin did not significantly reduce recurrent venous thromboembolism (VTE) or major bleeding and overall mortality compared to warfarin, but it did significantly reduce the risk of clinically relevant non-major bleeding in patients with active cancer.

Personalized Predictions for MS Prognosis May be Possible

Personalized Predictions for MS Prognosis May be Possible

A new model for predicting individualized prognosis in patients with multiple sclerosis (MS) has been developed, according to a new study published in the journal Statistical Methods in Medical Research.

FDA Expands Lymphoma Indication for Adcetris

FDA Expands Lymphoma Indication for Adcetris

Seattle Genetics announced that the Food and Drug Administration (FDA) has approved Adcetris (brentuximab vedotin) for Injection for the treatment of patients with classic Hodgkin lymphoma (HL) at high risk of relapse or progression post-autologous hematopoietic stem cell transplantation (auto-HSCT) consolidation.

Treatment-Resistant Lice Common Across the U.S.

Treatment-Resistant Lice Common Across the U.S.

Treatment-resistant lice with one or more genetic mutations have been identified in at least 25 states, according to research presented at the 250th National Meeting & Exposition of the American Chemical Society (ACS).

Microbiome May Help ID Women At Risk for Preterm Delivery

Microbiome May Help ID Women At Risk for Preterm Delivery

Significantly different microbiomes were seen in the reproductive tracts of pregnant women who had a baby born prematurely vs. women who delivered full term.

High Sodium Diet, Higher Risk of MS?

High Sodium Diet, Higher Risk of MS?

A high sodium diet may be a risk factor in developing multiple sclerosis (MS), according to a study in mice by researchers from the Federation of American Societies for Experimental Biology (FASEB).

Smoking Cessation Drug Not Improving Quit Rates, Says Study

Smoking Cessation Drug Not Improving Quit Rates, Says Study

Rather than increase the rate at which Americans successfully quit smoking, varenicline appears to have had no significant impact on the rates of smoking and the effectiveness is short-lived compared to other cessation aides.

Dice Throwing Test Shows Decision-Making Disability in MS Patients

Dice Throwing Test Shows Decision-Making Disability in MS Patients

Researchers found that multiple sclerosis (MS) patients have impaired decision-making abilities, especially as the disease progresses into the late stages, according to a new study from the University of Alberta's Faculty of Medicine & Dentistry and published in BMC Neurology.

Defective Sprays Prompt Recall of 350,000+ Inhalers

Defective Sprays Prompt Recall of 350,000+ Inhalers

Boehringer Ingelheim announced a voluntary recall of over 350,000 Combivent Respimat (ipratropium bromide, albuterol) inhalation sprays due to a defective delivery system.

Significant Improvements Seen With Stiolto Respimat in New Study

Significant Improvements Seen With Stiolto Respimat in New Study

Boehringer Ingelheim announced new data from a Phase 3b study of Stiolto Respimat (tiotropium, olodaterol) in which treatment with Stiolto Respimat led to significant improvements in SGRQ total score compared to placebo in patients with chronic obstructive pulmonary disease (COPD).

State Laws Lead to Small But Significant Dips in Opioid Prescribing

State Laws Lead to Small But Significant Dips in Opioid Prescribing

Two Florida laws aimed to reduce prescription drug abuse and misuse led to a small but significant decrease in the amount of opioids prescribed in the first 12 months of implementation, according to a study published in JAMA Internal Medicine.

Obesity Drug Labeling Updated with New Interaction, Side Effect

The Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) for Xenical (orlistat; Genentech) regarding new drug interactions and adverse reaction updates to its labeling.

Pentasa Caps Approved for New Administration Option

The Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) for Pentasa (mesalamine; Shire) regarding an update to its route of administration.

First-of-Kind Stem Cell-Based Tx Being Tested for Retinitis Pigmentosa

Scientists from the University of California, Irvine's Gavin Herbert Eye Institute and Sue & Bill Gross Stem Cell Research Center announced the start of patient enrollment for the first clinical trial evaluating the use of retinal progenitor cells to treat retinitis pigmentosa.

Low Vision Doesn't Always Mean No Driving

Low Vision Doesn't Always Mean No Driving

Patients with low vision may not be aware of their options for use of bioptic telescopic glasses while driving, but the International Academy of Low Vision Specialists (IALVS) has released information on individual state guidelines and requirements to help eligible patients earn or maintain their driver's license.

Epiduo Forte Gel Now Available for Acne Vulgaris

Epiduo Forte Gel Now Available for Acne Vulgaris

Galderma announced the launch of Epiduo Forte (adapalene and benzoyl peroxide) Gel for the once-daily, topical treatment of acne vulgaris.

Endophthalmitis Risk May Not Be Higher With Bevacizumab After All

Ophthalmic injections of bevacizumab exhibited no greater risk of endophthalmitis than injections of ranibizumab, according to a new study published in JAMA Ophthalmology.

Vitamin D Supplementation May Backfire for Obese Teens

Vitamin D Supplementation May Backfire for Obese Teens

Vitamin D supplementation in obese adolescents did not benefit their cardiovascular health or diabetes risk.

Antibiotic Injectable Coming Off FDA Shortage List

Antibiotic Injectable Coming Off FDA Shortage List

Baxter and Water Street Healthcare partners announced that the Food and Drug Administration (FDA) has approved Cefazolin Injection in Galaxy Container.

Low-Carb vs. Low-Fat Diet: Which Burns More Body Fat?

Low-Carb vs. Low-Fat Diet: Which Burns More Body Fat?

Cutting dietary fat led to 68 percent more body fat loss than cutting the same number of carbohydrate calories when adults with obesity consumed strictly controlled diets.

Oxycontin Approved for Pediatric Patients

Oxycontin Approved for Pediatric Patients

The Food and Drug Administration (FDA) announced that it has approved labeling updates for Oxycontin (oxycodone HCI; Purdue Pharma) extended-release tablets to expand the age range to include patients aged 11 and older for pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Protein Could Diagnose Alzheimer's in Earliest Stages

Protein Could Diagnose Alzheimer's in Earliest Stages

Researchers identified a new precursor protein in the earliest stages of Alzheimer's disease that begins the chain of processes leading to the loss of vital neurons in memory formation, according to a study published in the journal Molecular Psychiatry.

Patients May Not Benefit From Medical Foods for Metabolic Disorders

Patients May Not Benefit From Medical Foods for Metabolic Disorders

Medical foods designed for individuals with inborn errors of metabolism (IEMs) may actually cause harm in patients if their use is not carefully monitored and managed.

How Many Adults Are in Pain? NIH Study Offers Estimates

How Many Adults Are in Pain? NIH Study Offers Estimates

Research in The Journal of Pain has found that many American adults have recently experienced some level of pain, ranging from brief to chronic and from relatively minor to more severe.

Dental Visits: Opportunities for Drug Screenings?

Dental Visits: Opportunities for Drug Screenings?

According to researchers at Columbia University's Mailman School of Public Health, most dentists have asked their patient about illicit drug use but questions remain about the feasibility of offering preventive screening and testing alongside dental care.

Fewer Chickenpox Cases Today, Even Among the Non-immunized

Fewer Chickenpox Cases Today, Even Among the Non-immunized

A study in the Journal of the Pediatric Infectious Diseases Society reports that since a varicella virus (chickenpox) vaccine first became available in the United States, a significant reduction has been seen in varicella cases and a greater protection has been offered to those who are not immunized against the virus.

FDA Expands Bleeding Prevention Use for Wilate

FDA Expands Bleeding Prevention Use for Wilate

The Food and Drug Administration (FDA) has approved a new indication for Wilate (von Willebrand Factor/Coagulation Factor VIII Complex [Human]; Octapharma) for the prevention of excessive bleeding during and after minor and major surgery in adult and pediatric von Willebrand disease (VWD) patients.

Long-Term Safety, Efficacy Data Added in Sprycel Labeling

Bristol-Myers Squibb and Otsuka announced that the Food and Drug Administration (FDA) has approved an update to the Sprycel (dasatinib) labeling to include long-term efficacy data.

New Formulation of Onsolis Coming in 2016

BioDelivery Sciences International announced that the Food and Drug Administration (FDA) has approved a supplemental new drug application (sNDA) for a new formulation for Onsolis (fentanyl buccal soluble film) for the management of breakthrough pain in opioid-tolerant patients with cancer.

What Happens When Patients Get Access to Their Doctors' Notes

What Happens When Patients Get Access to Their Doctors' Notes

Sharing clinical notes with patients led to improved medication adherence and recall of treatment recommendations, according to a study in The Joint Commission Journal on Quality and Patient Safety.

New Study to Review Ticagrelor Monotherapy Post-PCI

New Study to Review Ticagrelor Monotherapy Post-PCI

The Icahn School of Medicine at The Mount Sinai Hospital announced the launch of an international clinical trial to evaluate the safety and efficacy of treating coronary stent patients with ticagrelor alone, rather than the current standard of care comprised of ticagrelor plus aspirin.

STAT3: New Target to Reverse Vision Loss in Macular Degeneration?

New research has revealed a specific pathway responsible for the formation of abnormal blood vessels that can cause blindness in age-related macular degeneration, according to a study published in the journal Nature Communications.

Investigational Agent for Huntington's Disease to Be Reviewed by FDA

The Food and Drug Administration (FDA) has accepted the New Drug Application (NDA) for SD-809 (deutetrabenazine, Teva) for the treatment of chorea associated with Huntington's disease (HD).

Venetoclax Demonstrates Efficacy in Phase 2 CLL Study

The Phase 2 trial of venetoclax (AbbVie) has met its primary endpoint in patients with relapsed/refractory or previously untreated chronic lymphocytic leukemia (CLL) with 17p deletion.

IBS-D Drug Launched as Two-Week Treatment Pack

IBS-D Drug Launched as Two-Week Treatment Pack

Salix announced the availability of Xifaxan 550mg in a new two-week treatment Pack.

Room for Improvement in Heart Disease Prevention Guidelines, Say Experts

Room for Improvement in Heart Disease Prevention Guidelines, Say Experts

Preventive cardiologists from Johns Hopkins and the Mayo Clinic have issued a list of suggested recommendations to the 2013 heart disease prevention guidelines issued by the American Heart Association and the American College of Cardiology (AHA/ACC).

Myrbetriq Gains New Contraindication, Warning

Myrbetriq Gains New Contraindication, Warning

The Food and Drug Administration (FDA) has approved changes to the Myrbetriq (mirabegron; Astellas Pharma) label to include a new contraindication and a new update to the Warnings and Precautions section.

Systemic Therapies for Pediatric Psoriasis Compared

Systemic Therapies for Pediatric Psoriasis Compared

The safety and efficacy of biologics in the treatment of pediatric psoriasis were demonstrated in several case studies published in the Journal of Drugs in Dermatology.

Physical Trauma Ups Psoriatic Arthritis Risk

Physical Trauma Ups Psoriatic Arthritis Risk

Psoriasis patients who experience physical trauma have an increased risk of developing psoriatic arthritis, according to a study presented at the European League Against Rheumatism Annual Conference (EULAR 2015) in Rome.

Greater Patient Satisfaction Seen With Biologics for Psoriasis

Greater Patient Satisfaction Seen With Biologics for Psoriasis

Patients taking biologic medications are more satisfied with their treatment and prefer longer dosing intervals compared to those taking other types of medicines for moderate to severe plaque psoriasis, reports a study in Patient Preference and Adherence.

Sign Up for Free e-newsletters