Warfarin Dosing Requirements May Differ By Race

Warfarin Dosing Requirements May Differ By Race

Findings from a recent study suggests that clinical and genetic factors affecting warfarin dose requirements differ by race.

Quinolone Antibiotic Currently in Shortage

Quinolone Antibiotic Currently in Shortage

The Food and Drug Administration (FDA) announced that Factive (gemifloxacin mesylate; LG Life Sciences) is currently in shortage.

Meropenem OK'd for Use in Infants Under 3 Months

Meropenem has been approved by the Food and Drug Administration (FDA) for the treatment of abdominal infections in infants less than 3 months old.

Novel Agent AMG 416 Effective in Secondary Hyperparathyroidism Trials

Novel Agent AMG 416 Effective in Secondary Hyperparathyroidism Trials

Amgen announced pooled data from two Phase 3 trials evaluating AMG 416 for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) receiving hemodialysis.

Rapamune Gains Rare Lung Disease Indication

Rapamune Gains Rare Lung Disease Indication

Pfizer announced that the Food and Drug Administration (FDA) has approved Rapamune (sirolimus), the first drug approved to stabilize lung function in patients with lymphangioleiomyomatosis (LAM).

NDA Submitted for Combination Chronic Hepatitis C Therapy

Merck has submitted a New Drug Application (NDA) to the Food and Drug Administration (FDA) for grazoprevir/elbasvir 100mg/50mg for the treatment of adults with chronic hepatitis C genotypes 1, 4, or 6 infection

Why Are Women More Likely to Develop MS Than Men?

The innate lymphoid cell has demonstrated different immune activities in males vs. females, researchers from the Northwestern Medicine lab have found.

Antiviral May Tighten Blood-Brain Barrier Against Pathogens

Antiviral May Tighten Blood-Brain Barrier Against Pathogens

Researchers have discovered that the antiviral interferon-lambda can tighten the blood-brain barrier, protecting the brain from invading viruses.

Better Outcomes for HIV Patients Who Start Treatment Early, Says Study

Better Outcomes for HIV Patients Who Start Treatment Early, Says Study

Preliminary findings from a study funded by the the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), indicate that HIV-infected individuals have a considerably reduced risk of developing AIDS or other serious illnesses if they initiate treatment with antiretroviral medications when their CD4+ T-cell count is higher, rather than waiting until this cell count drops to lower levels.

New OTC Lightweight Wearable Launched for Chronic Pain Relief

New OTC Lightweight Wearable Launched for Chronic Pain Relief

NeuroMetrix announced the launch of the Quell device for the treatment of chronic pain in patients with conditions such as diabetic nerve pain, low back and leg pain, fibromyalgia, and osteoarthritis pain.

FDA: Beware of Embolization With Dermal Fillers

FDA: Beware of Embolization With Dermal Fillers

The Food and Drug Administration (FDA) has issued an alert regarding certain injection sites on the face where unintentional injection of soft tissue fillers into blood vessels in the face can result in rare but serious side effects.

Which Tattoo Ink Colors Are Most Likely to Cause Skin Reactions?

Which Tattoo Ink Colors Are Most Likely to Cause Skin Reactions?

Researchers at the NYU Langone Medical Center have reported that up to six percent of adults in New York who get tattoos have experienced some form of tattoo-related rash, severe itching, or swelling that lasted from four months up to years for some.

Coagadex Amended BLA Under Review for Rare Bleeding Disorder

The Food and Drug Administration (FDA) has accepted for review the amended Biologics License Application (BLA) for Coagadex (coagulation factor X, human) for hereditary X deficiency.

Two Unique IBS-D Treatments Gain FDA Approval

Two Unique IBS-D Treatments Gain FDA Approval

The Food and Drug Administration (FDA) has approved Viberzi (eluxadoline; Actavis) and Xifaxan 550mg (rifaximin; Salix) for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.

Issues Raised on Telemedicine Antibiotic Prescribing in Study

Issues Raised on Telemedicine Antibiotic Prescribing in Study

A new RAND Corporation Study has shown that patients are more likely to be prescribed a broad-spectrum antibiotic for an acute respiratory infection by a doctor on a telephone or live video than face-to-face for the same illness.

Comorbidities May Significantly Up Mortality Risk in MS Patients

Patients with multiple sclerosis (MS) may have twice the mortality risk compared to those without MS, despite research indicating that MS survival may be improving over time. The results from this study were published in the journal Neurology.

NABP Hopes .Pharmacy Domain Will Help Weed Out Illegal Online Pharmacies

NABP Hopes .Pharmacy Domain Will Help Weed Out Illegal Online Pharmacies

The National Association of Boards of Pharmacy (NABP) announced that the general availability for the .pharmacy domain will begin on June 3, 2015 for pharmacies and pharmacy-related entities.

Gene Mutation in MS Sheds Light on Movement, Balance Disorders

Excessive inflammation that is present in multiple sclerosis (MS) may be due to a malfunctioning "brake" within immune cells to control the inflammation, researchers have concluded.

Pill Panic: Are Blood Clot Concerns Warranted?

Pill Panic: Are Blood Clot Concerns Warranted?

A study published in The BMJ suggests a link between newer contraceptive pills and higher risk of serious blood clots. The finding is not new, but it may be cause for a different kind of concern.

Humalog KwikPen Approved in New Strength

Humalog KwikPen Approved in New Strength

The Food and Drug Administration (FDA) has approved Humalog 200 units/mL KwikPen (insulin lispro 200 units/mL [U-200]; Eli Lilly) to improve glycemic control in patients with type 1 and type 2 diabetes.

Alzheimer's Drug Won't Be Discontinued After All

Actavis announced that it will continue to distribute Namenda (memantine HCI) tablets due to a recent decision by a panel of the U.S. Court of Appeals for the Second Circuit.

Low Doses of CO May Lessen Brain Damage Post-Hemorrhage

Low Doses of CO May Lessen Brain Damage Post-Hemorrhage

Results from a new study suggest that small controlled doses of carbon monoxide may protect the brain from damage after a subarachnoid hemorrhage by speeding up the clearance of heme that accumulates.

Vaccine to Treat Hypertension in the Works

Vaccine to Treat Hypertension in the Works

Researchers have created a DNA vaccine that may help reduce blood pressure for up to six months, new research published in the journal Hypertension has shown.

Results Announced From Phase 3 Trial of Combo COPD Therapy

Novartis announced results from its Phase 3 EXPEDITION trial for indacaterol/glycopyrronium (QVA149) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD).

Orphan Drug Status Granted to Ovarian Cancer Therapy

The Food and Drug Administration (FDA) has granted Orphan Drug designation to CRLX101 (Cerulean Pharma) for the treatment of ovarian cancer.

Overweight Male Teens Could Face Greater Bowel Cancer Risk in Future

Overweight Male Teens Could Face Greater Bowel Cancer Risk in Future

Very overweight male adolescents could have double the risk of developing bowel cancer later in life compared to those of normal weight, according to new research appearing in the journal Gut.

Lassa Fever Death Confirmed in N.J. Man

Lassa Fever Death Confirmed in N.J. Man

On May 25th, the Centers for Disease Control and Prevention (CDC) and the New Jersey Department of Health reported a death due to Lassa fever in a person returning to the United States from Liberia.

Do Soy Supplements Improve Lung Function in Uncontrolled Asthma?

Do Soy Supplements Improve Lung Function in Uncontrolled Asthma?

A new study published in JAMA has found that supplementation with soy isoflavone did not improve lung function or critical outcomes in patients with poor asthma control, despite previous research suggesting that it may be an effective treatment.

Par Launches Cortisporin-TC Otic Suspension

Par announced the launch of Cortisporin-TC (colistin sulfate, neomycin sulfate, thonzonium bromide, hydrocortisone acetate) Otic Suspension for the treatment of otitis externa caused by susceptible organisms and for the treatment of mastoidectomy and fenestration cavities caused by susceptible organisms.

Inhaled Statins: The Future of Asthma Treatment?

Inhaled Statins: The Future of Asthma Treatment?

Inhaled statins could become a novel class of inhaler therapy for airway diseases such as asthma, suggests a new study published in the journal Physiological Reports.

MS Gene Variant May Affect Treatment Response

MS Gene Variant May Affect Treatment Response

A genetic variant may be linked to a patient's likelihood of responding to interferon-beta therapy in multiple sclerosis (MS), according to a study published in the Annals of Neurology.

New Inhaler Option for COPD Now Approved

New Inhaler Option for COPD Now Approved

Boehringer Ingelheim announced that the Food and Drug Administration (FDA) has approved Stiolto Respimat (tiotropium bromide and olodaterol) Inhalation Spray for the long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

Heart Rate May Be an Indicator of Future Diabetes Risk

Heart Rate May Be an Indicator of Future Diabetes Risk

Heart rate measures may help identify a person's future risk of diabetes, researchers have proposed.

Can a Drug Used to Treat Stroke Be Effective for Otitis Media?

Can a Drug Used to Treat Stroke Be Effective for Otitis Media?

A drug to treat stroke showed efficacy in treating middle-ear infections by suppressing mucus overproduction, improving bacterial clearance, and reducing hearing loss, researchers from the Georgia State University and University of Rochester reported.

New ADHD Treatment Coming Soon

Aptensio XR (methylphenidate HCl extended-release) capsules will be available starting Summer 2015 for the treatment of attention deficit hyperactivity disorder (ADHD).

New Centrum MultiGummies Launched

Pfizer Consumer Healthcare announced the launch of Centrum MultiGummies, a multivitamin to help support energy, immunity, and metabolism.

Combination COPD Therapy Improves Lung Function in Trials

Boehringer Ingelheim announced new data analyses from the Phase 3 TONADO 1&2 studies of tiotropium/olodaterol delivered via Respimat inhaler for chronic obstructive pulmonary disease (COPD).

APAP Use During Pregnancy May Have Adverse Effect on Male Babies

APAP Use During Pregnancy May Have Adverse Effect on Male Babies

Prolonged acetaminophen use (1 week) by pregnant women may suppress fetal testosterone production, according to researchers from the University of Edinburgh.

Sarilumab Improves Physical Function in Rheumatoid Arthritis Trial

Regeneron and Sanofi announced results from their Phase 3 SARIL-RA-TARGET trial of sarilumab in patients with rheumatoid arthritis (RA).

Optina Efficacious in Diabetic Macular Edema Study

Ampio Pharmaceuticals announced positive results from the OptimEyes Trial for Optina in patients with diabetic macular edema (DME).

Dyanavel XR NDA Accepted for FDA Review

Tris Pharma announced that the Food and Drug Administration (FDA) has accepted for review its New Drug Application (NDA) for Dyanavel XR (amphetamine) CII, an Extended-Release Oral Suspension.

More Infections, Lower IQ? New Study Explores Link

More Infections, Lower IQ? New Study Explores Link

Infections may impair cognitive ability as measured on an IQ scale, data from a large study has shown.

Dosing Errors with Antibiotic Prompt FDA Warning

Dosing Errors with Antibiotic Prompt FDA Warning

The FDA is warning healthcare providers about the risk for dosing errors with Zerbaxa (ceftolozane and tazobactam; Cubist) due to confusion of the strength displayed on the vial and carton labeling.

Does Depression Increase the Risk of Parkinson's Disease?

Does Depression Increase the Risk of Parkinson's Disease?

Results from a large study show that people with depression may be more likely to develop Parkinson's disease.

Clinicians Need to Educate Consumers More About Food Safety

Healthcare providers at hospitals and physicians' offices are in an important position to ensure consumers about food safety, Michael Doyle, a Regents Professor in the department of food science and technology at the University of Georgia reported.

Boy or Girl? Fetal Sex May Impact GDM, T2DM Risk

Boy or Girl? Fetal Sex May Impact GDM, T2DM Risk

New research in the Journal of Clinical Endocrinology & Metabolism supports previous findings that fetal sex may be associated with an increased risk of gestational diabetes mellitus (GDM) or subsequent type 2 diabetes diagnosis after pregnancy.

Redesigned Antibiotic Shows Efficacy Against Common Bacterial Strains

Redesigned Antibiotic Shows Efficacy Against Common Bacterial Strains

Scientists have developed a second generation antibiotic that has demonstrated early efficacy against common bacterial infections.

Osteo Bi-Flex Now Available in Mini-Tabs

Osteo Bi-Flex Now Available in Mini-Tabs

Osteo Bi-Flex announced the launch of Osteo Bi-Flex EASE, a mini-tab supplement that promotes joint comfort through a novel collagen-based formula.

Imperfect Drug Penetration May Accelerate Pathogen Resistance

A pathogen can develop resistance faster in a "pocket" of the body where only one drug is present compared to where no pockets exist, a new study published in the Proceedings of the National Academy of Sciences has shown.

Naltrexone Tx for Meth Addiction Promising in Study

Naltrexone Tx for Meth Addiction Promising in Study

Naltrexone could be a promising adjunct pharmacologic treatment for methamphetamine addiction, as it significantly reduced cue-induced cravings and subjective responses to methamphetamine in this first-of-its-kind study to be conducted in the United States.

ICS Use in COPD Associated With Lower Pneumonia-Related, Overall Mortality

ICS Use in COPD Associated With Lower Pneumonia-Related, Overall Mortality

Treatment with inhaled corticosteroids (ICS) in patients with chronic obstructive pulmonary disease (COPD) may reduce the risk of death from pneumonia and other causes although they are associated an increased incidence of pneumonia, a meta-analysis presented at the 2015 American Thoracic Society International Conference has shown.

Rare Neurologic Disorder Therapy Designated Orphan Drug

Rare Neurologic Disorder Therapy Designated Orphan Drug

The Food and Drug Administration (FDA) has granted Orphan Drug designation to revusiran (Alnylam) for the treatment of transthyretin (TTR)-mediated amyloidosis (ATTR amyloidosis).

Investigational HCV Tx Receives Amended Breakthrough Designation

Investigational HCV Tx Receives Amended Breakthrough Designation

Bristol-Myers Squibb announced that the Food and Drug Administration (FDA) has amended a previously granted Breakthrough Therapy designation for the investigational daclatasvir and sofosbuvir combination for use in hepatitis C (HCV) patients.

Latuda for MDD With Mixed Features: New Results Announced

Latuda for MDD With Mixed Features: New Results Announced

Sunovion announced new results from the first placebo-controlled study evaluating Latuda (lurasidone HCl) in adults with major depressive disorder (MDD) who presented with mixed (subsyndromal hypomanic) features.

OTC IBgard Reduces Short-Term IBS Symptoms in Study

OTC IBgard Reduces Short-Term IBS Symptoms in Study

In a study presented at Digestive Disease Week (DDW), non-prescription IBgard led to a reduction in symptoms associated with irritable bowel syndrome (IBS), including unbearable and severe symptoms and abdominal pain intensity.

Depression and Diabetes: Prioritizing Treatment Goals

Depression and Diabetes: Prioritizing Treatment Goals

An article in The Lancet Diabetes & Endocrinology reviews evidence on screening and treatment for depression in adult patients with type 1 and type 2 diabetes and issues recommendations on treating these comorbid conditions.

Oral Steroids May Improve More Function than Pain in Sciatica

A short course of oral steroids provided modest improvement in function and no significant improvement in pain for patients with acute radiculopathy (sciatica), a study published in JAMA has shown.

Baby Teethers May Leach Chemicals From Plastics, Study Suggests

Baby Teethers May Leach Chemicals From Plastics, Study Suggests

Some plastic teethers for babies may contain endocrine disrupting chemicals, a new study has found.

New Schizophrenia Treatment Allows for Quarterly Dosing

New Schizophrenia Treatment Allows for Quarterly Dosing

Janssen announced that the Food and Drug Administration (FDA) has approved Invega Trinza (paliperidone palmitate) extended-release injectable suspension, the first and only medication indicated for the treatment of schizophrenia in adults that requires administration only four times per year and provides the longest dosing interval currently available.

Treating Overactive Bladder May Reduce Fall Risk in Elderly

Treating Overactive Bladder May Reduce Fall Risk in Elderly

A new study has shown that treatment for overactive bladder (OAB) may lead to less falls among older adults.

Progression-Free Survival Seen With Enzalutamide for Prostate Cancer in Phase 2 Trial

Astellas Pharma and Medivation announced data from the Phase 2 STRIVE trial comparing Xtandi (enzalutamide) and bicalutamide in non-metastatic (M0) and metastatic (M1) prostate cancer patients whose disease progressed despite treatment with a luteinizing hormone-releasing hormone (LHRH) analogue therapy of following surgical castration.

Solifenacin + Mirabegron Shows Superiority in Incontinent Overactive Bladder Trial

Astellas Pharma announced results from the Phase 3b BESIDE trial with solifenacin (SOLI) with mirabegron (MIRA) as an add-on therapy in incontinent overactive bladder (OAB) patients.

Luspatercept Fast Tracked for Two Beta-Thalassemia Indications

The Food and Drug Administration (FDA) has granted Fast Track designations to luspatercept (Celgene and Acceleron) for use in two separate indications: for the treatment of patients with transfusion dependent beta-thalassemia and for the treatment of patients with non-transfusion dependent beta-thalassemia.

Understanding CNS Origins in Fibromyalgia: Treatment Recommendations

Understanding CNS Origins in Fibromyalgia: Treatment Recommendations

Research supporting the neurological basis for fibromyalgia, a chronic central nervous system (CNS) disorder, was presented at the American Pain Society Annual Scientific Meeting.

Real-World Data on A1c Reduction With Invokana Announced

Real-World Data on A1c Reduction With Invokana Announced

Janssen announced data from three real-world analyses for Invokana (canagliflozin) in adults with type 2 diabetes.

FDA Website to Curb Drug Purchasing from Unlicensed Distributors

FDA Website to Curb Drug Purchasing from Unlicensed Distributors

The Food and Drug Administration (FDA) has issued a warning to healthcare providers on the purchasing of counterfeit, unapproved, or otherwise unsafe prescription drugs from unauthorized or unlicensed distributors.

Key Factors for Predicting COPD Exacerbations Identified

Key Factors for Predicting COPD Exacerbations Identified

Researchers presented key risk factors that can help identify patients at risk for acute exacerbations of their chronic obstructive pulmonary disease (COPD), at the 2015 American Thoracic Society International Conference.

Regular Aspirin May Slow Emphysema Progression

Regular Aspirin May Slow Emphysema Progression

Regular aspirin use is associated with a slower progression of early emphysema on computed tomography (CT) scans over the course of 10 years, according to research presented the 2015 American Thoracic Society International Conference.

AEs With Movantik, Placebo Compared in Analyses of Elderly Patients

AEs With Movantik, Placebo Compared in Analyses of Elderly Patients

Movantik (naloxegol; AstraZeneca) was found to have a similar incidence of adverse events among elderly patients as compared to placebo or usual care, safety analyses presented at Digestive Disease Week 2015 have shown.

Study on NFL Retirees Reveals Impact of Concussion History on Memory

Study on NFL Retirees Reveals Impact of Concussion History on Memory

Research suggests that a history of concussion with loss of consciousness may be associated with increased brain atrophy in the area involved with storing memory and impaired memory performance.

Xiaflex Label Updated With Contracture Recurrence Data

Xiaflex Label Updated With Contracture Recurrence Data

Endo announced that the Food and Drug Administration (FDA) has approved a label update for Xiaflex (collagenase clostridium histolyticum) for the treatment of adult Dupuytren's contracture (DC) patients with a palpable cord.

Namzaric Launched for Alzheimer's Disease

Namzaric Launched for Alzheimer's Disease

Actavis announced that Namzaric (memantine HCl extended-release and donepezil HCl) capsules have launched for the treatment of moderate to severe Alzheimer's disease in patients stabilized on memantine HCl and donepezil HCl.

Guidelines for Preventing Conflicts Between ICU Patient's Family, Clinicians

Guidelines for Preventing Conflicts Between ICU Patient's Family, Clinicians

A new policy statement from the American Thoracic Society provides guidance for crucial decision-making for intensive care patients while preventing conflicts between medical staff and family caregivers. The guideline appears in the American Journal of Respiratory and Critical Care Medicine.

More Weight Loss Predicted for Early Responders to Saxenda

More Weight Loss Predicted for Early Responders to Saxenda

Results from the SCALE Obesity and Pre-diabetes trial showed that adults who were early responders to Saxenda had greater weight loss after completing 56 weeks along with a reduced-calorie diet and increased physical activity vs. those who were early nonresponders.

Bleeding Outcomes for Elderly NVAF Patients on Xarelto Announced

Bleeding Outcomes for Elderly NVAF Patients on Xarelto Announced

New data presented at the American Geriatrics Society 2015 Annual Scientific meeting suggests that the rates of major bleeding and fatal outcomes in elderly patients with non-valvular atrial fibrillation (NVAF) treated with Xarelto (rivaroxaban; Janssen) are consistent with those reported in Phase 3 clinical trials.

New Blood Test Detects IBS Biomarkers for Fast Diagnosis

New Blood Test Detects IBS Biomarkers for Fast Diagnosis

Commonwealth announced the launch of IBSchek, a blood test to guide physicians in the diagnosis of irritable bowel syndrome (IBS).

FDA: Warning Issued for Newer Class of Type 2 Diabetes Meds

FDA: Warning Issued for Newer Class of Type 2 Diabetes Meds

The Food and Drug Administration (FDA) is warning that certain medications indicated for the treatment of type 2 diabetes may lead to ketoacidosis, the production of high levels of blood acids that could require hospitalization.

Humira Designated Orphan Drug for Painful, Inflammatory Skin Disease

AbbVie announced that the Food and Drug Administration (FDA) has granted Orphan Drug designation for Humira (adalimumab) as an investigational treatment for moderate-to-severe hidradenitis suppurativa (HS; Hurley Stage II and III disease).

Diabetes Drug May Improve Glucose, Inflammation in HIV+ Patients

Diabetes Drug May Improve Glucose, Inflammation in HIV+ Patients

A drug indicated for the treatment of type 2 diabetes improved metabolism and reduced inflammation in HIV-positive adults taking antiretroviral therapy, which could reduce the risk of cardiovascular disease and diabetes due to chronic inflammation.

Xarelto Studied in NVAF Patients Undergoing Catheter Ablation

Xarelto Studied in NVAF Patients Undergoing Catheter Ablation

Janssen and Bayer HealthCare announced results from the VENTURE-AF trial that compared Xarelto (rivaroxaban) as an alternative to vitamin K antagonists (VKA) to reduce the risk of blood clots in patients with non-valvular atrial fibrillation (NVAF) undergoing catheter ablation.

First Combo Rx for Adolescent Migraines Approved

First Combo Rx for Adolescent Migraines Approved

Pernix announced that the Food and Drug Administration (FDA) has approved Treximet (sumatriptan, naproxen sodium) for use in pediatric patients aged 12 and older for the acute treatment of migraine with or without aura.

There May Be Gluten in Your Probiotic, Says New Study

There May Be Gluten in Your Probiotic, Says New Study

An analysis performed by researchers at the Celiac Disease Center at Columbia University Medical Center shows that more than half of popular probiotics contain traces of gluten.

Efficacy of Ophthalmic NSAIDs for Common Indications Compared

Efficacy of Ophthalmic NSAIDs for Common Indications Compared

A recent review compared published data from 67 articles on the efficacy of diclofenac, ketorolac, flurbiprofen, bromfenac, and nepafenac within and outside their FDA-approved uses.

Vitamin B3 May Reduce Recurrence of Some Skin Cancers in High-Risk Patients

Vitamin B3 May Reduce Recurrence of Some Skin Cancers in High-Risk Patients

A study presented at the American Society of Clinical Oncology's (ASCO) 51st Annual Meeting found that an over-the-counter form of vitamin B3 significantly reduced rates of new non-melanoma skin cancers in high-risk patients, which along with sun protection could help to decrease the health and economic burden of skin cancer.

Anesthesia With Better Recovery for Infants ID'ed in Two Studies

Anesthesia With Better Recovery for Infants ID'ed in Two Studies

Infants that receive regional anesthesia vs. general anesthesia for surgery may have better recovery, data from two studies have shown.

Can Infant Antibiotic Use Lead to Disease Later in Life?

Can Infant Antibiotic Use Lead to Disease Later in Life?

Scientists at the University of Minnesota have created a predictive model for measuring healthy development of bacteria in the gut of young children and a framework to map potential links between antibiotics, gut bacteria, and disease later in life.

Grip Strength: A New Measurement for CVD Mortality Risk?

Grip Strength: A New Measurement for CVD Mortality Risk?

New research published in The Lancet suggests that testing grip strength could be a quick, low-cost screening tool for clinicians to identify patients at a greater risk of mortality due to cardiovascular and non-cardiovascular disease (such as cancer).

FDA Rejects Claim That Smokeless Tobacco is Safer Than Cigarettes

FDA Rejects Claim That Smokeless Tobacco is Safer Than Cigarettes

The Food and Drug Administration (FDA) has denied a Citizen Petition requesting the initiation of a rulemaking to change a tobacco warning statement required on smokeless tobacco products.

PTSD, Cancer Not Linked in Largest Study to Date

PTSD, Cancer Not Linked in Largest Study to Date

While the potential relationship between stress and cancer has been a topic of discussion and research for over 70 years, no association between post-traumatic stress disorder (PTSD) and cancer was found in the largest study to date and published in the European Journal of Epidemiology.

Hysingla ER Long-Term Safety, Efficacy Data Released

Hysingla ER Long-Term Safety, Efficacy Data Released

Purdue announced data from a long-term safety and efficacy study of Hysingla ER (hydrocodone bitartrate extended-release) tablets with abuse-deterrent properties.

FDA Panel Backs Approval of CF Drug Orkambi

Vertex announced that the Food and Drug Administration's (FDA) Pulmonary-Allergy Drugs Advisory Committee (PADAC) has voted 12 to 1 to recommend that the FDA approve Orkambi (lumacaftor/ivacaftor) for people with cystic fibrosis (CF) aged 12 and older who have two copies of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

Alcohol Use Disorder, Smoking Rates Far Exceed Illicit Drug Use Worldwide

Alcohol Use Disorder, Smoking Rates Far Exceed Illicit Drug Use Worldwide

About 240 million people have an alcohol use disorder and over one billion people smoke tobacco, according to a new study published in the journal Addiction.

Lifetime Ban on Blood from MSM Donors May Be Over Soon

Lifetime Ban on Blood from MSM Donors May Be Over Soon

The Food and Drug Administration (FDA) has issued a draft guidance for blood establishments that collect blood or blood components with recommended revisions to the donor deferral period for men who have sex with men (MSM).

E. coli Survival, Growth in IBD Flares Explained

E. coli Survival, Growth in IBD Flares Explained

Researchers have established a new defense mechanism to explain how Escherichia coli can thrive during flare ups in patients with inflammatory bowel disease (IBD).

Drop in Codeine Rx to Postpartum Women Seen After FDA Advisory

Drop in Codeine Rx to Postpartum Women Seen After FDA Advisory

A new study in JAMA reports that a significant reduction in the rate of dispensing of codeine to postpartum women was observed following public health advisories from the U.S. Food and Drug Administration (FDA) and Health Canada on potentially life-threatening adverse effects in infants of breastfeeding mothers taking codeine.

Evofosfamide Fast Tracked for Advanced Pancreatic Cancer

The Food and Drug Administration (FDA) has granted Fast Track status to evofosfamide (Merck KGaA) in combination with gemcitabine, for the treatment of previously untreated patients with metastatic or locally advanced unresectable pancreatic cancer.

Study: 9-Valent HPV Vaccine Could Prevent 80% of Cervical Cancers

Study: 9-Valent HPV Vaccine Could Prevent 80% of Cervical Cancers

A study by the Centers for Disease Control and Prevention (CDC) and Cedars-Sinai proposes that the 9-valent human papillomavirus (HPV) vaccine could prevent 80 percent of cervical cancers in the United States if administered to all 11- or 12-year-old children prior to exposure to the virus.

Contrave CV Outcomes Study Terminated Early

Takeda and Orexigen announced the early termination of the Light Study, a cardiovascular (CV) outcomes trial following the recommendation of the Executive Steering Committee (ESC).

E-Reminders at Office Visit May Boost HPV Vaccination Rates

E-Reminders at Office Visit May Boost HPV Vaccination Rates

A simple electronic reminder during an office visit may encourage more patients to get the human papillomavirus (HPV) vaccine to protect against cervical cancer, researchers have found.

Senza System Offers SCS for Pain Without Paresthesia

Senza System Offers SCS for Pain Without Paresthesia

Nevro announced that the Food and Drug Administration (FDA) has approved the Senza System, a spinal cord stimulation (SCS) system as an aid in the management of chronic intractable pain of the trunk and/or limbs, including pain associated with failed back surgery syndrome, low back pain, and leg pain.

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