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NULEV
Cough and cold
Hyperacidity, GERD, and ulcers
Parkinsonism
Poisoning/overdose
Urinary tract discomfort
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Drug Name:

NULEV Rx

Generic Name and Formulations:
Hyoscyamine sulfate 0.125mg; chewable melt tabs; peppermint flavor.

Company:
Meda Pharmaceuticals

Therapeutic Use:

Indications for NULEV:

As a drying agent in the relief of symptoms of acute rhinitis.

Adults and Children:

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Pharmacological Class:

Anticholinergic.

Contraindications:

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Warnings/Precautions:

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Adverse Reactions:

Anticholinergic effects (e.g., drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

How Supplied:

Tabs—100

Indications for NULEV:

Adjunct in irritable bowel syndrome, peptic ulcer, spastic or functional GI disorders, neurogenic bowel disorders, colic.

Adults and Children:

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Pharmacological Class:

Anticholinergic.

Contraindications:

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Warnings/Precautions:

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Adverse Reactions:

Anticholinergic effects (e.g., drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

How Supplied:

Tabs—100

Indications for NULEV:

Parkinsonism: to reduce rigidity and tremors and to control associated sialorrhea and hyperhidrosis.

Adults and Children:

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Pharmacological Class:

Anticholinergic.

Contraindications:

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Warnings/Precautions:

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Adverse Reactions:

Anticholinergic effects (e.g., drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

How Supplied:

Tabs—100

Indications for NULEV:

Anticholinesterase poisoning.

Adults and Children:

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Pharmacological Class:

Anticholinergic.

Contraindications:

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Warnings/Precautions:

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Adverse Reactions:

Anticholinergic effects (e.g., drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

How Supplied:

Tabs—100

Indications for NULEV:

Lower urinary tract spasm.

Adults and Children:

<2yrs: not recommended. 2–12yrs: ½–1 tab every 4 hrs or as needed; max 6 tabs/day. ≥12yrs: 1–2 tabs every 4 hrs or as needed; max 12 tabs/day. Tabs may be chewed or dissolved on tongue and swallowed.

Pharmacological Class:

Anticholinergic.

Contraindications:

Glaucoma. GI or urinary tract obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon. Myasthenia gravis.

Warnings/Precautions:

High environmental temperature. Fever. Diarrhea: exclude partial GI obstruction. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hypertension. CHF. Arrhythmias. Tachycardia. Renal disease. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Additive effects with other anticholinergics, amantadine, haloperidol, phenothiazines, MAOIs, tricyclic antidepressants, antihistamines. Antacids may inhibit absorption.

Adverse Reactions:

Anticholinergic effects (e.g., drowsiness, dizziness, blurred vision, urinary hesitancy, palpitations, mydriasis, dry mouth), nausea, taste loss, impotence, rash, confusion, psychosis.

How Supplied:

Tabs—100

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