Generic Name and Formulations:
Insulin aspart protamine suspension 70% (recombinant), insulin aspart 30% (recombinant) 100 Units/mL; SC inj; contains zinc, m-cresol.
Company:
Novo Nordisk
Diabetes.
For SC inj only. Onset approx ≤15 minutes, peak approx 2.4 hours, duration up to 24 hours.
Not recommended.
During episodes of hypoglycemia.
Instruct patients on diet, exercise, blood or urine testing, proper administration of insulin, change in species of origin, type or purity of insulin, and management of hypoglycemia. Dosage increase may be required during infection, illness, stress, trauma, and pregnancy. Dosage decrease may be needed with renal or hepatic dysfunction. Pregnancy (Cat.B). Nursing mothers.
Potentiated by oral antidiabetic agents, pramlintide, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, propoxyphene, salicylates, somatostatin analog, sulfonamide antibiotics. Antagonized by corticosteroids, isoniazid, niacin, danazol, diuretics, thiazides, phenothiazines, sympathomimetics, somatropin, thyroid hormones, estrogens, progestogens, atypical antipsychotics. Variable effects with β-blockers, clonidine, lithium salts, alcohol, pentamidine. Do not mix with other insulins.
Hypoglycemia, hypokalemia, local or systemic allergy, lipodystrophy, edema.
Vials (10mL)—1
FlexPen (3mL prefilled syringe)—5