NICOTROL NS Rx

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NICOTROL NS

Smoking
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Generic Name and Formulations:

Nicotine 0.5mg/spray; aqueous nasal spray.

Select therapeutic use:

Indications for NICOTROL NS:

Adjunct in smoking cessation therapy.

Adult:

Do not sniff, swallow, or inhale. Individualize. Usually 1–2 doses/hour; max 5 doses/hour, 40 doses/day for up to 3 months; may discontinue abruptly or taper.

Children:

Not recommended.

Contraindications:

Concurrent smoking or other nicotine products.

Warnings/Precautions:

Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Hepatic or severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Peptic ulcer disease. Elderly. Low doses may be toxic to children and pets. Nasal Spray not recommended in chronic nasal disorders. Pregnancy (Cat.D), labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.

Interactions:

Nasal Spray antagonized by nasal vasoconstrictors. Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.

See Also:

NICOTROL INHALER

Adverse Reactions:

Local irritation, GI upset, headache, dizziness, palpitations, hypertension.

How Supplied:

Inhaler 42 cartridges—1 (w. inhaler and case); Nasal Spray 10mL (200 sprays)—1 (w. metered spray pump)