Study: HIV Gel May Work Post-Exposure
the MPR take:
A study published in the journal Science Translational Medicine explores the use of a post-coital vaginal gel that could potentially protect against HIV infection. Typically, microbicide gels have contained antiretroviral drugs that block the early steps of virus infection. This requires the gel to be applied before sex, which may decrease compliance. In this study, the vaginal gel contained raltegravir, an integrase strand inhibitor that blocks the late steps after viral infection. Researchers discovered that the application of topical integrase inhibitors could protect against viral infection if given right before or 3 hours after exposure. A vaginal gel that works post-exposure could help to prevent the spread of HIV especially in cases of rape.
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