Regular Aspirin Use May Reduce Pancreatic Cancer Risk

Ever-regular use associated with lowered risk, with 8% decrease for each cumulative year of use
Ever-regular use associated with lowered risk, with 8% decrease for each cumulative year of use

HealthDay News — Regular aspirin use is associated with reduced risk of pancreatic cancer in a Chinese cohort, according to a study published online December 20 in Cancer Epidemiology, Biomarkers & Prevention.

Harvey A. Risch, MD, PhD, from the Yale School of Public Health in New Haven, Connecticut, and colleagues conducted a population-based study involving 761 case and 794 control subjects, frequency matched on sex and age during 2006 to 2011 in China. Participants were asked about aspirin use. 

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The researchers observed a correlation for ever-regular use of aspirin with lower risk of pancreatic cancer (odds ratio, 0.54). For each cumulative year of use the risk decreased 8% (odds ratiotrend, 0.92). For any aspirin type and for low-dose aspirin, the odds ratios for ever-regular use decreased with increasingly more recent mid-study year across 18 other published studies of this association.

"In conclusion, we observed a significant inverse relationship between aspirin use and risk of pancreatic cancer in a large representative sample of Chinese individuals," the authors write. "The pattern of risk reduction was very similar to that seen in other recent studies in the United States and elsewhere."

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