Polyethylene Glycol vs. Pulsed Irrigation Evacuation for Colon Prep

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Randomized study found pulsed irrigation evacuation, sodium phosphate to be superior
Randomized study found pulsed irrigation evacuation, sodium phosphate to be superior

HealthDay News — Pulsed irrigation evacuation (PIE) and sodium phosphate are superior to polyethylene glycol (PEG) for colon preparations prior to colonoscopy, according to a study published online November 21 in the Journal of Digestive Diseases.

Kamran Ayub, MD, from Silver Cross Hospital in New Lenox, Ill., and colleagues compared screening colonoscopy colon prep methods: PIE (135 patients), PEG (129 patients), and sodium phosphate (127 patients) among 391 outpatients at a Veterans Affairs hospital (mean age, 62 years; 75% men).

The researchers found that PIE and sodium phosphate were superior to PEG, with both receiving a score of 4 on a 5-point scale (blind assessment), versus a 3 for PEG (P<0.01). PEG was associated with more inadequate preps, compared to PIE (18 vs. 5%; P<0.01). Vomiting was reported in 37% of patients with sodium phosphate, 5 percent with PEG, and 2% with PIE (P<0.01). 

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"PIE would be the preferred preparation for those at high risk for unsatisfactory preparations or with unsatisfactory traditional preparations," the authors write.

PIE Medical International donated the PIE machine and supplies for this study.

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