Prevalence and Severity of Clostridium difficile Infection Among Children

the MPR take:

As part of the Emerging Infections Program (EIP), researchers sought a population-based study of Clostridium difficile infection (CDI) rates among children. Using data from 10 geographic areas during the years 2010 and 2011, there were 944 reported cases of pediatric CDI. 71% of these cases were community-associated (CA) and severity was uniform across all age groups. The incidence of CDI was highest among white children and those 12–23 months old. Antibiotic use during the 14 days prior to CDI-positive stool detection was 33% across all age groups. For CA CDI cases, 73% reported recent antibiotic use. The authors argue that this data bolsters the need for effective antibiotic stewardship programs.

Prevalence and Severity of Clostridium difficile Infection Among Children
Prevalence and Severity of Clostridium difficile Infection Among Children
OBJECTIVE: Little is known about the epidemiology of Clostridium difficile infection (CDI) among children, particularly children 3 years of age in whom colonization is common but pathogenicity uncertain. We sought to describe pediatric CDI incidence, clinical presentation, and outcomes across ...

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