Rate of Metformin Use Examined Among Prediabetics

Metformin use low even among those with a body mass index of ≥35 kg/m²
Metformin use low even among those with a body mass index of ≥35 kg/m²

HealthDay News — For U.S. adults with prediabetes, the prevalence of metformin use is 0.7%, according to a study published online April 3 in Diabetes Care.

Eva Tseng, MD, from Johns Hopkins University in Baltimore, and colleagues estimated the age-adjusted prevalence of metformin use among individuals with prediabetes and examined characteristics associated with metformin use using data from the National Health and Nutrition Examination Survey 2005 to 2012. 

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The researchers found that 7,652 of 22,174 adults had prediabetes. Among those with prediabetes, the age-adjusted prevalence of metformin use was 0.7%. Metformin use correlated with elevated body mass index (BMI) (35.1 versus 29.6 kg/m²) and with higher glucose (fasting glucose, 114 versus 105 mg/dL; two-hour post-stimulated glucose, 155 versus 128 mg/dL; and hemoglobin A1c, 6.0 versus 5.6%). Even among those with a BMI ≥35 kg/m², metformin use was low. There was no variation in metformin use by race, poverty-to-income ratio, or education.

"Metformin use was <1% among U.S. adults with prediabetes and only slightly more common among those with additional risk factors for diabetes" the authors write.

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