High-Dose Flu Vaccine May Be More Effective for These Patients

High-Dose Flu Vaccine May Be More Effective for These Patients
High-Dose Flu Vaccine May Be More Effective for These Patients

A recent study from the Veterans Affairs found that the high-dose influenza vaccine is most effective for those aged ≥85 years. Findings from the study are published in Clinical Infectious Diseases.

People aged 65–84 years benefit from the standard vaccine just as well, researchers reported. They sought to determine if a specific age bracket within the elderly population made a difference in vaccine response. The study tracked hospitalizations and deaths in over 165,000 Veterans Affairs patients who received either the regular or high-dose vaccine during the 2010–2011 season. Data showed no difference in overall outcome between the two groups. A secondary analysis showed, however, there was a stronger effect for patients aged ≥85 years.

RELATED: Over 40,000 Deaths Prevented With Flu Vaccine, CDC Says

Results from this study contrast with those from other published studies. One study conducted by the Food and Drug Administration (FDA) showed that the high-dose vaccine was 22% more effective at preventing flu-related hospital admissions during the 2012–2013 season. Another study of older adults published in the New England Journal of Medicine showed that the high-dose vaccine better protected against lab-confirmed flu than the standard-dose vaccine and it triggered more antibodies during 2011–2013.

Researchers note more research is needed across multiple years to reach a more definitive conclusion.

For more information visit VA.gov.

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