Links Between Bacterial Infection and Gallbladder Disease Investigated

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Cholecystic polyps more common, gallstones less common with infection, the researchers found
Cholecystic polyps more common, gallstones less common with infection, the researchers found

HealthDay News — Gallstones are less common with Helicobacter pylori infection among a Chinese population, according to a study published November 27 in the Journal of Gastroenterology & Hepatology.

Mei-Yan Xu, from the Aerospace Center Hospital in Beijing, and colleagues assessed the relationship between H. pylori infection and gallbladder diseases among 17,971 healthy participants. 

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The researchers found that 43.4% of participants had H. pylori infection, 5.5% had gallstones, 1.2% had cholecystitis, and 5.6% had cholecystic polyps. Among participants ≤45 years in the H. pylori-positive group, the prevalence of gallstones was lower than in the H. pylori-negative group (odds ratio, 0.653). In the H. pylori-positive group, the prevalence of cholecystic polyps was significantly higher than that seen in the H. pylori-negative group (odds ratio, 1.160).

"H. pylori infection is found to be related to cholecystic polyps and gallstones," the authors write.

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