First Tx for Hereditary Factor X Deficiency Now Available

Blood Test Could ID Young Males At Risk for Autism
Blood Test Could ID Young Males At Risk for Autism

Coagadex (coagulation Factor X [human]; Bio Products Laboratory) is now available for patients ≥12 years old with hereditary Factor X deficiency for on-demand treatment and control of bleeding episodes, and perioperative management of bleeding in patients with mild hereditary Factor X deficiency.

Coagadex is the only specific Factor X concentrate available in the United States. It works by temporarily replacing the missing Factor X needed for effective homeostasis. Factor Xa, its active form, associates with Factor Va on a phospholipid surface to form the prothrombinase complex, which activates prothrombin to thrombin in the presence of calcium ions. Thrombin then acts upon soluble fibrinogen and Factor XIII to generate a cross-linked fibrin clot.

RELATED: Coagadex Approved for Hereditary Factor X Deficiency

Coagadex will be available through specialty pharmacies and authorized distributors with specialized disease state and product training.  It is supplied in single-use vials containing a nominal 250 IU or 500 IU Factor X activity. 

For more information call (844) 4BPLUSA or visit Coagadex.com.

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